Protein-Lipid Interactions

Edited By

  • A. Watts, Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK

Protein-lipid interactions as a field of study is now a mature area, and this volume of NewComprehensive Biochemistry has been published with two objectives in mind. Firstly, to look to thefuture, and try to envisage how the subject may develop in the near to medium future. Secondly, to presentcontrasting or complementary views on the same system. For example, the acetylcholine receptor is discussedfrom a predominantly structural aspect by Barrantes, and from the kinetic standpoint by Rankin, et al.

The volume not only gives an update on specific aspects of the field, but also shows the way in whichthe phenomenon of protein-lipid interactions is now seemingly infiltrating many areas of biomembraneresearch, from recombinant DNA studies, protein insertion and assembly and reconstitution considerationsto structural studies of membrane proteins.

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Book information

  • Published: October 1993
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-81575-0


Table of Contents

(a full list of contents is available from the Publisher on request). Preface. List of Contributors. Chapter 1.Protein-lipid interactions and membrane heterogeneity (O.G. Moutitsen, R.L. Biltonen). 2. The nature of the lipid-protein interface and the influence of protein structure on protein-lipid interactions (D. Marsh). 3.Cooperative regulation of membrane enzymes by lipids (H. Sandermann Jr., T.M. Duncan, J.O. McIntyre,S. Fleischer). 4. Lipid-protein interaction in a biological membrane: Effect of cholesterol and acyl chaindegree of unsaturation (C.E. Castuma, M.T. Lamy-Freund, R.R. Brenner, S. Schreier). 5. Lipid-peptideinteractions in model systems: Membrane insertion and translocation of peptides (A.I.P.M. de Kroon, J. deGier, B. de Kruijff). 6. Protein-lipid interactions with peripheral membrane proteins (M.B. Sankaram, D.Marsh). 7. Genetic studies on the functions of membrane-forming phospholipids (T.P. McGee, M.K.Y. Fung,V.A. Bankaitis). 8. Lipid-protein interactions involved in bacteriophage M13 infection (M.A. Hemminga, J.C.Sanders, C.J.A.M. Wolfs, R.B. Spruijt). 9. Functional aspects of acetylcholine receptor-lipid interactions (S.E.Rankin, D.E. Raines, L.A. Dalton, K.W. Miller). 10. The lipid annulus of the nicotinic acetylcholine receptoras a locus of structural-functional interactions (F.J. Barrantes). 11. The(Ca2+-Mg2+)-ATPase and other membrane proteins: whatreconstitution tells us about the biological membrane (A.G. Lee, J.M. East). 12. The functional effects ofprotein and lipid dynamics in sarcoplasmic reticulum (D.D. Thomas, J.E. Mahaney). 13. Infraredspectroscopic studies of lipid-protein interactions in membranes (J.L.R. Arrondo, F.M. Goñi). 14.Lipid-protein interactions in controlled membrane protein array and crystal formation (A. Watts, C.Vénien-Bryan, M. Sami, C. Whiteway, J. Boulter, B. Sternberg). Index.