Principles of Bone Biology book cover

Principles of Bone Biology

Two-Volume Set

Academic and medical libraries as well as professionals in bone biology, endocrinology, and osteology.


Imprint: Academic Press

ISBN: 978-0-12-373884-4


  • PREVIOUS EDITION PRAISE "Students, teachers, and practitioners will benefit from reading it, and investigators will use it as a reference work; it will certainly be consulted frequently."--The New England Journal of Medicine


  • Part IBasic PrinciplesA. Cell BiologyChapter 1: Structure, Modeling and Remodeling of Bone / The Size and Shape of Bone as a Site of Metabolic Bone ActivityEgo SeemanChapter 2:Biomechanics of BoneElise MorganChapter 3:Embryonic Development of Bone and the Molecular Regulation of Intramembranous and Endochondral Bone FormationAndrew KaraplisChapter 4: Mesenchymal Stem Cells & Osteoblast LineageJane AubinChapter 5:Transcriptional Control of Osteoblast Differentiation and FunctionThorsten SchinkeChapter 6:Wnt Signaling and BoneMark JohnsonChapter 7:Sclerostin and BoneRutger van BezooijenChapter 8:The OsteocyteJenneke Klein-NulendChapter 9:Cells of Bone: Osteoplast GenerationTatsuo SudaChapter 10:Osteoclast Function: Biology and MechanismsKalervo VaananenChapter 11:RANK SignalingHiroshi TakanayagiChapter12:Regulating Bone ResorptionRoland BaronChapter 13:Apoptosis in Bone CellsStavros ManolagasChapter 14:Skeletal Gene Expression in Nuclear MicroenvironmentsGary SteinB. BiochemistryChapter 15: Type I Collagen: Structure, Synthesis, and RegulationBenoit de CrombruggheChapter 16:Collagen Crosslinking & MetabolismSimon RobinsChapter 17:Bone Matrix Proteoglycans & GlycoproteinsPamela RobeyChapter 18:OsteopontinMasaki NodaChapter 19:Bone ProteinasesNicola PartridgeChapter 20:Integrins and Other Cell Surface Attachment Molecules of Bone CellsMichael HortonChapter 21:Intercellular Junctions and Cell-Cell Communication in the Skeletal SystemRoberto CivitelliC. Bone Remodeling and Mineral HomeostasisChapter 22:Histomorphometric Analysis of Bone RemodelingDavid DempsterChapter 23:Phosphorus Homeostasis & Related DisordersMarc DreznerChapter 24:Magnesium HomeostasisRobert RudeChapter 25:Metals in Bone: Aluminum, Boron, Cadmium, Chromium, Lead, Silicon, & StroFelix BronnerChapter 26:Biology of the Extracellular Ca2+-Sensing Receptor Edward BrownD. The Hormones of BoneChapter 27:Receptors for Parathyroid Hormone (PTH) and PTH-Related ProteinJohn PottsChapter 28:Parathyroid Hormone - Molecular BiologyHank KronenbergChapter 29:Parathyroid Hormone-Receptor InteractionsMike RosenblattChapter 30:Actions of Parathyroid Hormone on the Vasculature and Cardiovascular SystemJohn BilezikianChapter 31:The Vascular and Cardiovascular Actions of PTHJohn BilezikianChapter 32:PTH and PTHrP Actions on Kidney and BonePeter FriedmanChapter 33:Physiological Actions of Parathyroid Hormone and PTH-Related ProteinJohn WysolmerskiChapter 34:Vascular, Cardiovascular and Neurological Actions of Parathyroid-Related ProteinThomas ClemensChapter 35:Vitamin D Nuclear Receptor (VDR) and Plasma Vitamin D-Binding Protein (DBP) Structures and Ligand Shape Preferences for Genomic and Rapid Biological ResponsesTony NormanChapter 36:Vitamin D Gene RegulationSylvia ChristakosChapter 37:Photobiology and Non-Calcemic Actions of Vitamin DMike HolickChapter 38:Calcitonin Structure and Molecular Biology of the Calcitonin Receptor / Calcitonin Gene Family and Receptors: Structure, Molecular Biology, and EffectsBob GagelChapter 39:Amylin and Calcitonin Gene-Related PeptideJill CornishE. Other Systemic Hormones That Influence Bone MetabolismChapter 40:Estrogens & ProgestinsRussell TurnerChapter 41:The Pharmacology of Selective Estrogen Receptor ModulatorsHenry BryantChapter 42:Mechanisms of Estrogen Action in BoneRoberto PacificiChapter 43:Thyroid Hormone & BonePaula SternChapter 44:Clinical and Basic Aspects of Glucocorticoid Action in BoneBarbara KreamChapter 45:Effects of Diabetetes & Insulin on Bone PhysiologyJohan VerhaegheChapter 46:Androgens:Receptor Expression and Steroid Action in BoneKristine WirenChapter 47:Kinins & Neuro-Osteogenic FactorsUlf LernerChapter 48:Regulation of Bone Remodeling by Central and Peripheral Nervous SignalsPatricia DucyF. Local RegulatorsChapter 49: Insulin-like Growth Factors and the IGF Binding Proteins: Implications for Bone BiologyCliff RosenChapter 50:Platelet-Derived Growth Factor & the SkeletonErnesto CanalisChapter 51:Fibroblast Growth Factor (FGF) and FGF Receptor Families in BoneMarja HurleyChapter 52:Vascular Endothelial Growth Factor and Osteogenic-Angiogenic CouplingDwight TowlerChapter 53:Transforming Growth Factor- Sarah DallasChapter 54:Bone Morphogenetic Proteins and the Skeleton Vicki RosenChapter 55:Bone Morphogenetic Protein Receptors & ActionsKohei MiyazonoChapter 56:Colony-Stimulating Factor-1Willy HofstetterChapter 57:Local Regulators of Bone: IL-1, TNF, Lymphotoxin, Interferon-?, IL-8, IL-10, IL-4, the LIF/IL-6 Family, and Additional CytokinesMark HorowitzChapter 58:Prostaglandins & Bone MetabolismCarol PilbeamPart IIMolecular Mechanisms of Metabolic Bone DiseaseChapter 59:Skeletal Effects of Nitric Oxide: Novel Agent for OsteoporosisSunil WimalawansaChapter 60:Molecular Basis of PTH OverexpressionAndy ArnoldChapter 61:Familial Benign Hypocalciuric Hypercalcemia and Neonatal Primary HyperparathyroidismGhada EI-Hajj FuleihanChapter 62:Multiple Endocrine Neoplasia Type IMaria Luisa BrandiChapter 63:Parathyroid Hormone-Related Peptide and Other Systemic Factors in Skeletal Manifestations of MalignancyDavid GoltzmanChapter 64:Local Factors in Skeletal MalignancyGreg MundyChapter 65:Genetic Regulation of the Parathyroid Gland DevelopmentRaj ThakkerChapter 66:Jansen's Metaphyseal Chondrodysplasia & Blomstrand's Lethal Chondrodysplasia: Two Genetic Disorders Caused by PTH/PTHrP Receptor MutationsHarald JueppnerChapter 67:Diseases Resulting from Defects in the G Protein GsLee WeinsteinChapter 68:Renal Osteodystrophy ? Pathogenic Mechanisms and Therapeutic OptionsBill GoodmanChapter 69:Osteogenesis ImperfectaDavid RoweChapter 70:Hereditary Deficiencies in Vitamin D ActionUri LibermanChapter 71:Oncogenic OsteomalaciaSuzanne Jan de BeurChapter 72:OsteopetrosisLyndon KeyChapter 73:Hypophosphatasia: Nature's Window on Alkaline Phosphatase Function in HumansMichael WhyteChapter 74:Paget's Disease of BoneFred SingerChapter 75:Genetic Determinants of Bone Mass and Osteoporotic FractureStuart RalstonChapter 76:Pathophysiology of OsteoporosisBilezikian, Raisz, MartinChapter 77:Evaluation of Risk for Osteoporosis FractureStuart SilvermanPart IIIPharmacological Mechanisms of TherapeuticsChapter 78:Parathyroid HormoneDave HanleyChapter 79:CalciumRobert HeaneyChapter 80:Drugs Acting on the Calcium Receptor Calcimimetics and CalcilyticsEdward NemethChapter 81:Bisphosphonates: Mechanisms of ActionGraham RussellChapter 82:The Pharmacology of Estrogens in OsteoporosisRobert LindsayChapter 83:Vitamin D & AnalogsGlenville JonesChapter 84:Estrogen Effects on Bone in the Male SkeletonLuigi GennariChapter 85:Mechanisms of Exercise Effects on Bone Quantity and QualityClint RubinPart IVMethods in Bone ResearchChapter 86:Application of Transgenic Mice to Problems of Skeletal BoneStephen ClarkChapter 87:Biochemical Markers of Bone MetabolismMarkus SeibelChapter 88:Methods and Clinical Issues in Bone DensitometryGlen BlakeChapter 89:Controversial Issues in Bone DensitometryPaul MillerChapter 90:Macro and Micro Imaging of Bone ArchitectureKlaus Engelke, Sven Prevrhal, and Harry K. Genant


advert image