Polyphenols in Human Health and Disease book cover

Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more.


Nutritionists, dieticians, and clinical researchers interested in how the mechanisms of polyphenols contribute to the prevention and treatment of disease

Hardbound, 1488 Pages

Published: November 2013

Imprint: Academic Press

ISBN: 978-0-12-398456-2


  • Part I: Biomodification of polyphenols and mechanisms of action

    Section 1 O: Overview of polyphenols and health research

    Section 1 A: Absorption, metabolism and bioavailability of polyphenols

    1 A-1 Absorption of polyphenols

    1 A-2 Metabolism in the gut

    1 A-3 Bioavailability in vivo

    Section 1 B: Effect of microbes on polyphenol structure and function

    1B-1 Bacteria’s actions on polyphenols

    1B-2 Anti-bacterial actions of polyphenols

    1B-3 Health effects of biomodification by microbes

    Section 1 C: Polyphenol actions as enzyme modulators in health

    Section 1 D: Oxidation and antioxidant activity of polyphenols

    1 D-1: Polyphenolic antioxidants in health promotion

    1 D-2: Mechanisms of polyphenols antioxidants

    Section 1 E: Toxicities and identification of polyphenols

    1 E-1: Toxicities of polyphenols

    1 E-2: Polyphenols identification and occurrence

    1 E-3: Safety of polyphenols

    Part II: Polyphenols in prevention and treatment of chronic disease

    Section 2 A: Polyphenols and vascular health

    2 A-1: Vascular protection by polyphenols

    2 A-2: Endothelial function and polyphenols

    Section 2 B: Cardiac health and polyphenols

    2 B-1 Mechanisms of polyphenolic cardiac modification


    2 B-2 Polyphenols in treatment and prevention of cardiac disease

    Section 2 C: Polyphenols in therapy of obesity and diabetes

    2 C-1: Polyphenols and diabetes

    2 C-2: Obesity and polyphenols

    2 C-3: Polyphenolic regulation of metabolism

    Section 2 D: Polyphenols in brain and neurobiology health

    2 D-1: Polyphenols in health and function of the brain

    2 D-2: Mechanisms of polyphenols in neurobiology

    Section 2 E: Cancer prevention and treatment by polyphenols

    2 E1: Mechanisms of polyphenol modulation of cancer

    2 E2: Polyphenols and tumor growth

    2 E3: Cancer prevention by polyphenols

    Section 2 F: Inflammation and immune functions

    2 F1: Inflammation and polyphenols

    2 F2: Polyphenols in immune regulation

    Section 2 G: Diverse diseases and physiological states modified by polyphenols

    2 G1: Inflammatory diseases modified by polyphenols

    2 G2: Physiological states modified by polyphenols

    2 G3: Polyphenols in clinical medicine

    2 G4: Mechanisms of polyphenols action in clinical medicine


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