Organic Chemistry book cover

Organic Chemistry

Structure, Mechanism, and Synthesis

There are no shortcuts in organic chemistry. Understanding and mastery cannot be achieved without devoting adequate time and attention to the theories and concepts of the discipline. It is with this premise that Ouellette and Rawn set out to comprehensively survey the field in Organic Chemistry, with an emphasis on connecting the basic principles of organic chemistry to real world challenges that require analysis, not just recall.

Organic chemistry is at the interface of physical and biological science, and this new text lays out the basic principles of organic chemistry in their relation to a host of other fields in both physical and biological sciences. Chemical bonding determines molecular structure, which in turn dictates physical, chemical, and biological properties from the smallest molecules to the largest. Molecular structure determines reaction mechanisms, from the smallest to the largest molecules. Reaction mechanisms determine strategies for organic synthesis, and these synthetic principles extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, wherein principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the text and real world applications.


Chemists, life scientists, food scientists, pharmacists, students in the physical and life sciences

Hardbound, 1240 Pages

Published: June 2014

Imprint: Elsevier

ISBN: 978-0-12-800780-8


  • "...a good investment for undergraduate students studying organic, medicinal or biological chemistry...should also be appealing to those who teach organic chemistry at undergraduate level."-Education in Chemistry, Nov,14-2014


  • Preface
    1. Structure and Bonding in Organic Compounds
    2. Part I: Functional Groups and Their Properties
    2. Part II: Identification of Functional Groups by Infrared Spectroscopy
    3. Introduction to Organic Reaction Mechanisms
    4. Alkanes and Cycloalkanes: Structures and Reactions
    5. Alkenes Structures and Properties
    6. Alkenes: Addition Reactions
    7. Alkynes
    8. Stereochemistry
    9. Haloalkanes and Alcohols Introduction to Nucleophilic Substitution and Elimination Reactions
    10. Nucleophilic Substitution and Elimination Reactions
    11. Conjugated Alkenes and Allylic Systems
    12. Arenes and Aromaticity
    13. Electrophilic Aromatic Substitution
    14. Methods for Structure Determination Nuclear Magnetic Resonance and Mass Spectrometry
    15. Alcohols: Reactions and Synthesis
    16. Ethers and Epoxides
    17. Organometallic Chemistry of Transition Metal Elements and Introduction to Retrosynthesis
    18. Aldehydes and Ketones
    19. Aldehydes and Ketones: Nucleophilic Addition Reactions
    20. Carboxylic Acids
    21. Carboxylic Acid Derivatives
    22. Condensation Reactions of Carbonyl Compounds
    23. Amines and Amides
    24. Aryl Halides, Phenols, and Anilines
    25. Pericyclic Reactions
    26. Carbohydrates
    27. Amino Acids, Peptides, and Proteins
    28. Synthetic Polymers


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