Organic Chemistry

Structure, Mechanism, and Synthesis


  • Robert Ouellette, Emeritus Professor, The Ohio State University, Columbus, OH, USA
  • J. David Rawn, Towson University, Baltimore, MD, USA

There are no shortcuts in organic chemistry. Understanding and mastery cannot be achieved without devoting adequate time and attention to the theories and concepts of the discipline. It is with this premise that Ouellette and Rawn set out to comprehensively survey the field in Organic Chemistry, with an emphasis on connecting the basic principles of organic chemistry to real world challenges that require analysis, not just recall.

Organic chemistry is at the interface of physical and biological science, and this new text lays out the basic principles of organic chemistry in their relation to a host of other fields in both physical and biological sciences. Chemical bonding determines molecular structure, which in turn dictates physical, chemical, and biological properties from the smallest molecules to the largest. Molecular structure determines reaction mechanisms, from the smallest to the largest molecules. Reaction mechanisms determine strategies for organic synthesis, and these synthetic principles extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, wherein principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the text and real world applications.

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Chemists, life scientists, food scientists, pharmacists, students in the physical and life sciences


Book information

  • Published: June 2014
  • Imprint: ELSEVIER
  • ISBN: 978-0-12-800780-8


"...a good investment for undergraduate students studying organic, medicinal or biological chemistry...should also be appealing to those who teach organic chemistry at undergraduate level."-Education in Chemistry, Nov,14-2014

Table of Contents

1. Structure and Bonding in Organic Compounds
2. Part I: Functional Groups and Their Properties
2. Part II: Identification of Functional Groups by Infrared Spectroscopy
3. Introduction to Organic Reaction Mechanisms
4. Alkanes and Cycloalkanes: Structures and Reactions
5. Alkenes Structures and Properties
6. Alkenes: Addition Reactions
7. Alkynes
8. Stereochemistry
9. Haloalkanes and Alcohols Introduction to Nucleophilic Substitution and Elimination Reactions
10. Nucleophilic Substitution and Elimination Reactions
11. Conjugated Alkenes and Allylic Systems
12. Arenes and Aromaticity
13. Electrophilic Aromatic Substitution
14. Methods for Structure Determination Nuclear Magnetic Resonance and Mass Spectrometry
15. Alcohols: Reactions and Synthesis
16. Ethers and Epoxides
17. Organometallic Chemistry of Transition Metal Elements and Introduction to Retrosynthesis
18. Aldehydes and Ketones
19. Aldehydes and Ketones: Nucleophilic Addition Reactions
20. Carboxylic Acids
21. Carboxylic Acid Derivatives
22. Condensation Reactions of Carbonyl Compounds
23. Amines and Amides
24. Aryl Halides, Phenols, and Anilines
25. Pericyclic Reactions
26. Carbohydrates
27. Amino Acids, Peptides, and Proteins
28. Synthetic Polymers