Oligomerization and Allosteric Modulation in G-Protein Coupled Receptors
Edited by- Terry Kenakin, PhD, Professor of Pharmacology, The University of North Carolina at Chapel Hill
In this thematic volume of
Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique qualities that make GPCRs a crucial tool in microbiological and cancer research.
Audience
Researchers of G-protein receptors, molecular biology, and translational science
Hardbound, 488 Pages
Published: March 2013
Imprint: Academic Press
ISBN: 978-0-12-394587-7
Contents
- Approaches for Probing Allosteric Interactions at 7 Transmembrane Spanning Receptors
- Pharmacology of Metabotropic Glutamate Receptor Allosteric Modulators: Structural Basis and Therapeutic Potential for CNS Disorders
- Mining the Potential of Label-Free Biosensors for Seven-Transmembrane Receptor Drug Discovery
- G Protein-Coupled Receptors in Cancer : Biochemical Interactions and Drug Design
- GPCRs in Stem Cell Function
- Application of Receptor Theory to Allosteric Modulation of Receptors
- What Ligand-Gated Ion Channels Can Tell Us about the Allosteric Regulation of G protein-Coupled Receptors
- Modelling Cooperativity Effects in Dimeric G Protein-Coupled Receptors
- Chemokine Receptor Oligomerization and Allostery
- Fine-Tuning of GPCR Signals by Intracellular G Protein Modulators
Peishen Zhao, Wendy Cladman, Hubert HM Van Tol and Peter Chidiac
Michael T. Klein, Paige N. Vinson and Colleen M. Niswender Karen J. Gregory, Meredith J. Noetzel and Colleen M. Niswender Magalie Rochville, Julio Martin, Jeffrey Clifford Jerman & Evi Kostenis Yves Audigier, François-Xavier Picault, Carline Chaves-Almagro and Bernard Masri Van A. Doze and Dianne M. Perez David A. Hall Frederick J. Ehlert Jesús Giraldo Bryan Stephens and Tracy M. Handel
