Nuclear Receptors and Genetic Disease book cover

Nuclear Receptors and Genetic Disease

Nuclear Receptors and Genetic Disease provides the first compilation of the role of nuclear hormones in health and disease and incorporates the latest breakthroughs in the field. It provides comprehensive reviews of the major receptors prepared by the acknowledged experts in each area. Each chapter provides information on the history, physiology, structure, mechanism of action, genetics, pathophysiology, disease diagnosis, and disease treatment for a particular nuclear receptor. Each chapter also includes a table showing all the known mutations of the respective nuclear receptor with the corresponding clinical disorder.

Audience
Research level biochemists, molecular biologists, cell and developmental biologists, those working in pharmacology, endocrinology and reproductive biology, and clinical researchers/ clinicians in endocrinology (diabetes and metabolism), clinical genetics, oncology, OBS/gynecology.

Hardbound, 419 Pages

Published: September 2000

Imprint: Academic Press

ISBN: 978-0-12-146160-7

Contents

  • List of Contributors.The Nuclear Receptor Superfamily, T.P. Burris.Thyroid Hormone Receptors, U. Dressel and A. Baniahmad.Estrogen and Progesterone Receptors, G.F. Allan.The Androgen Receptor, G. Jenster, J. Trapman and A.O. Brinkman.DAX-1 and Related Orphan Receptors, E. Vilain and E.R.B. McCabe.The Vitamin D Receptor, P.N. MacDonald, D.M. Kraichely and A.J. Brown.Retinoid Receptors, A.C.-K. Chung and A.J. Cooney.Mineralocorticoid and Glucocorticoid Receptors, T. Kino, A. Vottero and G.P. Chrousos.Hepatocyte Nuclear Factor 4α, F.M. Sladek and S.D. Seidel.Peroxisome Proliferator-Activated Receptors (PPAR), A. Elbrecht, A. Adams and D.E. Moller.Coactivators and Corepressors,D.M. Lonard and Z. Nawaz.Index.

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