Molecular Aspects of Transport Proteins

Edited By

  • J.J.H.H.M. de Pont

The development of molecular biological techniques and their application in the field has given a new dimension to the area of membrane transport. The combination of biochemical (site-specific reagents), molecular biological (site-directed mutagenesis) and genetic approaches of which this volume gives numerous examples in combination with biophysical techniques as X-ray analysis and NMR will eventually lead to a complete elucidation of the mechanism of action of these transport proteins.

Although impossible to give a comprehensive overview of this rapidly expanding field, the expert contributors discuss: pumps involved in primary active transport, carriers which transport metabolites, and channels which allow selective passive transport of particular ions.

This volume is ideal for teachers, students and investigators in this field, and will lead to further progress in our understanding of this fascinating field.

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Book information

  • Published: November 1992
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-89562-2

Table of Contents

1. Na, K-ATPase, Structure and Transport Mechanism: (P.L. Jørgensen).2. Structure and Function of Gastric H,K-ATPase: (T.J.F. van Uem, J.J.H.H.M.De Pont). 3. The Ca2+ Transport ATPase of Sarco[endo]-plasmicReticulum and Plasma Membranes: (A. Martonosi). 4. The Neurosporacrassa Plasma Membrane H+-ATPase: (G.A. Scarborough). 5. Theclass II enzymes of the Phosphoenolpyruvate-Dependent Carbohydrate TransportSystems: (J.S. Lolkema, G. Robillard). 6. Mechanisms of Active and PassiveTransport in a Family of Homologous Sugar Transporters (S.A. Baldwin). 7. Amino-Acid Transporters inYeast: Structure, Function, and Regulation: (M. Grenson). 8. Stucture andFunction of Plasma Membrane Na+/H+ Exchangers: (P.Igarashi). 9. Cl- Channels: (R. Greger). 10. Voltage-Gated K+Channels: (O. Pongs). 11. Structure and Regulation of Voltage-Dependent L-type Calcium Channels: (M.M. Hosey, R.M. Brawley, C.F. Chang, L.M. Gutierrez,C. Mundina-Weilenmann). Index.