Infection and Autoimmunity book cover

Infection and Autoimmunity

Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity.

Hardbound, 768 Pages

Published: September 2004

Imprint: Elsevier

ISBN: 978-0-444-51271-0


  • List of Contributors

    Introduction: Infection and Autoimmunity

    I Mechanisms of Autoimmune Induction by Infection

    Implications of T Cell Receptor Crossreactivity for the Pathogenesis of Autoimmune Diseases

    Epitope Spreading

    Molecular Mimicry in Multiple Sclerosis: Role of MHC-Altered Peptide Ligands (MAPL)

    Adverse Events of Desirable Gain in Immunocompetence: The Immune Restoration Inflammatory Syndromes (IRIS)

    CD5-Expressing B Cells and Infection

    Endothelial Cell Autoreactivity and Infection

    II Vaccination

    Induction of Autoimmunity by Adjuvant Hydrocarbons

    Vaccination and Autoimmunity

    BCG Vaccination

    III Viruses

    Viruses: The Culprits of Autoimmune Diseases?

    How Transgenic Mouse Models Contribute to a Better Understanding of Virus-Induced Autoimmunity

    Epstein-Barr Virus and Autoimmunity

    HIV and Autoimmunity

    Parvovirus B19 Infection and Its Association to Autoimmune Disease

    Hepatitis C Infection and Vasculitis

    HCV and Cryoglobulinemia

    Virus-Induced Systemic Vasculitides

    Viral Infections and Autoimmune Hepatitis

    Viral Infections and Type 1 Diabetes

    Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease (TMEV-IDD) and Autoimmunity

    Viruses and Multiple Sclerosis

    Endogenous Retroviruses as Etiological Agents in Systemic Lupus Erythematosus

    Sjögren's Syndrome - Autoimmune Epithelitis: Role of Coxsackieviruses in Pathogenesis

    Viral Infection and Heart Disease: Autoimmune Mechanisms

    IV Bacteria and Autoimmunity

    Rheumatic Fever: How Streptococcal Throat Infection Triggers an Autoimmune Disease

    Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)

    Helicobacter Pylori Infection and Gastric Autoimmunity: Coincidence or Cause-Effect Relationship?

    Yersinia Enterocolitica Infections and Autoimmune Thyroid Diseases

    Reactive Arthritis (Reiter's Syndrome): Roles of Infection, HLA-B27 and the Immune Response

    Bovine Spongiform Encephalopathy as an Autoimmune Disease Evoked by Acinetobacter: Implications for Multiple Sclerosis and Creutzfeldt-Jakob Disease

    Infection and Autoimmunity in Patients with Antibiotic Treatment-Resistant Lyme Arthritis

    Post-Infectious Arthritis: Reactive Arthritis or Slow Infectious Arthritis?

    V Parasites and Autoimmunity

    Parasitic Infection and Autoimmunity

    Autoimmunity in Chagas' Disease

    Anti-Saccharomyces Cerevisiae Antibodies and Autoimmune Diseases

    VI Infection and Diseases

    The Infectious Origin of the Antiphospholipid Syndrome

    SLE and Infections

    Type I Diabetes Mellitus, Infection and Toll-like Receptors

    Infection and Autoimmune Thyroid Diseases

    Pemphigus and Infection

    Infection, Autoimmunity and Autoimmune Liver Diseases

    Infections and Vasculitis

    Infection and Multiple Sclerosis

    Infections and Polymyositis-Dermatomyositis

    Infection and Guillain-Barré Syndrome

    Infection and Systemic Sclerosis

    Tuberculosis and SLE-like Symptoms as a Complication of Biological Anti-TNF Therapy

    Infection and Behçet's Syndrome

    Infections and Immune Thrombocytopenic Purpura

    Inflammatory Bowel Disease

    Infection and Spondyloarthropathies

    Celiac Disease and Infection

    Infections Associated with Retinal Autoimmunity

    Infection and Atherosclerosis

    The Pathogenic Role of Heat Shock Proteins in Atherosclerosis

    Interaction between Rheumatoid Arthritis and Infections

    Subject Index


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