High Throughput Analysis for Early Drug Discovery
- James Kyranos, ArQule, Inc., Woburn, MA, USA
- Published: September 2004
- Imprint: ACADEMIC PRESS
- ISBN: 978-0-12-431165-7
"The volume provides useful information to scientists interested in the topic specially organic and analytical chemists dealing with drug development and discovery and therefore it would be highly recommended."
Hassan Y. Aboul-Enein, Centre for Clinical Research, Saudi Arabia, BIOMEDICAL CHROMATOGRAPHY, 2005
"Overall this book is very informative and meets its goal of enlightening readers about current high-throughput analysis methods used to analyze combinatorial products. "
ANAL BIOANAL CHEM (2006) 385, Sapna Deo, Indiana University, IN, USA
Table of ContentsHigh Throughput Analysis of Combinatorial Libraries Encoded with Electrophoric Molecular Tags, Adolor Corporation (J. Guo et al.).
Analysis of a Combinatorial Library Synthesized Using a Split-and-pool Irori MicroKan Method for Development and Production, Boehringer Ingelheim Pharmaceuticals, Inc. (H. Lee, C.R. Sarko).
High-Throughput Mass Spectrometry-Flow Injection Analysis, Procter and Gamble Pharmaceuticals (K.L.Morand).
High-Throughput Flow-Injection ESI and APCI Mass Spectrometry for Combinatorial Chemistry: Automated Acquisition and Interpretation for Multi-Sprayer Low-Resolution and FTMS High-Resolution Exact-Mass Measurements, Wyeth Research (C. Truebenbach et al.).
Purity and Quantity Determination of Parallel Synthesis Compound Libraries, ArQule, Inc. (J. Delaney et al.).
High-Throughput Parallel LC/MS/ELSD of Combinatorial Libraries Using the Eight-Channel LCT System With MUX Technology, Nereus Pharmaceuticals Inc and University of California, San Diego (P.W. Davis, M.C. Griffith).
Purification and Analysis of Parallel Libraries, Albany Molecular (C. Garr).
Screening Single Bead Combinatorial Libraries Using Capillary HPLC and MALDI-TOF-MS, National Research Council (D.A. Voller et al.).
The Role of NMR in the Analysis of Chemical Libraries, Bristol Meyers Squibb (S.W. Gerritz, A. M. Sefler).