Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus book cover

Glucose Homeostatis and the Pathogenesis of Diabetes Mellitus

Diabetes mellitus is a disease with tremendous health and economic burden. A better understanding of how normal glucose homeostasis is maintained and the pathogenesis is important to identify new ways for diabetes treatment. This book addresses multiple aspects of this area of research.


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine, biomedical scientists and clinicians.

Hardbound, 536 Pages

Published: January 2014

Imprint: Academic Press

ISBN: 978-0-12-800101-1


    "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--BRITISH MEDICAL JOURNAL


    1. G Protein-Coupled Receptors as Regulators of Glucose Homeostasis and Therapeutic Targets for Diabetes Mellitus
      Ya-Xiong Tao and Xu-Fang Liang
    2. Regulation of Glucose Homeostasis by GLP-1
      Prashant Nadkarni, Oleg G. Chepurny and George G. Holz
    3. Physiology and Therapeutics of the Free Fatty Acid Receptor GPR40
      Hui Huang, Meng-Hong Dai and Ya-Xiong Tao
    4. Targeting GPR119 for the Potential Treatment of Type 2 Diabetes Mellitus
      Xiu-Lei Mo, Zhao Yang and Ya-Xiong Tao
    5. Enhanced Skeletal Muscle for Effective Glucose Homeostasis
      Jinzeng Yang
    6. Factors Affecting Insulin-regulated Hepatic Gene Expression
      Hong-Ping Guan and Guoxun Chen
    7. Roles of Peroxisome Proliferator-Activated Receptors (PPARs) in the Metabolic Syndrome
      Mahmoud Mansour
    8. Free Fatty Acids and Skeletal Muscle Insulin Resistance
      Lyudmila I. Rachek
    9. Adiponectin Signaling and Metabolic Syndrome
      Yuchang Fu
    10. Regulation of Pancreatic Islet Beta-Cell Mass by Growth Factor and Hormone Signaling
      Yao Joyce Huang and Yongchang Chang
    11. The Impact of Dietary Methionine Restriction on Biomarkers of Metabolic Health
      Manda L. Orgeron, Kirsten P. Stone, Desiree Wanders, Cory C. Cortez, Nancy T. Van and Thomas W. Gettys
    12. Carbohydrate Metabolism and Pathogenesis of Diabetes Mellitus in Dogs and Cats
      Margarethe Hoenig
    13. Impaired Insulin Signaling and Mechanisms of Memory Loss
      Jenna Bloemer, Subhrajit Bhattacharya, Rajesh Amin and Vishnu Suppiramaniam
    14. The Role of PPARd  Signaling in the Cardiovascular System
      Yishu Ding, Kevin D. Yang and Qinglin Yang


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