Fidelity and Quality Control in Gene Expression
The goal of this volume is to provide a comprehensive mechanistic and quantitative view of the processes that mediate or influence the quality control in translation. In addition to discussing processes with direct contribution to translation fidelity, such as aminoacylation of tRNAs and translation elongation itself, special attention is given to other processes with impact on quality control: detection and elimination of defective mRNAs, recycling and translation re-initiation, mRNA editing, and translational recoding through programmed frame-shifting.
Biochemists, biophysicists, cell biologists, protein chemists, structural geneticists, and structural biologists
Advances in Protein Chemistry and Structural Biology
Hardbound, 272 Pages
Published: January 2012
Imprint: Academic Press