Extracellular Matrix and The Liver
Approach to Gene Therapy
- Isao Okazaki, Tokai University School of Medicine, Tokyo, Japan
- Yosifumi Ninomiya, Okayama University Medical School, Japan
- Tanikawa Kyuichi, Kurume University School of Medicine, Japan
- Scott Friedman, Mount Sinai School of Medicine, New York, NY, USA
Extracellular Matrix of the Liver addresses the basic science of the extracellular matrix and discussesnew strategies for the treatment of cirrhosis of the liver, with a primary focus on possible gene therapyapproaches.The chapters are divided into six sections as follows:* Basic Science of Extracellular Matrix* Cells Responsible for Extracellular Matrix Production* Activation Mechanism of Hepatic Cells and Signal Transduction* Basic Science for Extracellular Matrix Metabolism including Enzymes and their Inhibitors* Matrix Mettaloproteinases and Tissue Inhibitors for Matrix Mettaloproteinases * New Strategies for the treatment of Liver Cirrhosis
Hepatologists, molecular geneticists, gastroenterologists, oncologists, and hematologists.