Eukaryotic Transcription Factors book cover

Eukaryotic Transcription Factors

Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events.

Audience
This book is a mandatory resource for any researcher or student in the life sciences.

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Published: September 2007

Imprint: Academic Press

ISBN: 978-0-12-373983-4

Contents

  • DNA sequences, transcription factors and chromatin structure; Methods for studying transcription factors; RNA polymerases and the basal transcriptional complex; Families of DNA binding transcription factors; Activation of gene expression by transcription factors; Repression of gene expression by transcription factors; Regulation of transcription factor synthesis; Regulation of transcription factor activity; Transcription factors and human disease

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