Essential Concepts in Molecular Pathology
- William Coleman, Professor, Department of Pathology and Laboratory Medicine, UNC Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA
- Gregory Tsongalis, Professor of Pathology, Director, Molecular Pathology, and Co-Director Translational Research Program, Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
AudienceGraduate students in allied health programs, medical students, undergraduate students; pathology residents and other postdoctoral residents and fellows interested in the molecular mechanisms of disease.
- Published: February 2010
- Imprint: ACADEMIC PRESS
- ISBN: 978-0-12-374418-0
Table of Contents
PART I Essential Pathology - Mechanisms of Disease
Chapter 1 Cell Injury, Cell Death, and Cellular Adaptation
John J. Lemasters, M.D., Ph.D.
Chapter 2 Acute and Chronic Inflammation
Vladislav Dolgachev, Ph.D. and Nicholas W. Lukacs, Ph.D.
Chapter 3 Infection and Host Response
Sheldon M. Campbell, M.D., Ph.D. and Margret Oethinger, M.D.,Ph.D.
Chapter 4 Neoplasia
William B. Coleman, Ph.D., and Tara Rubinas, M.D.
PART II Concepts in Molecular Biology and Genetics
Chapter 5 Basic Concepts in Human Molecular Genetics
W. Edward Highsmith, Ph.D., and Kara A. Mensink, M.S., C.G.C.
Chapter 6 The Human Genome: Implications for the Understanding of Human Disease
William B. Coleman, Ph.D, Gregory J. Tsongalis, Ph.D. and Ashley Rivenbark, M.D.
Chapter 7 The Human Transcriptome: Implications for the Understanding of Human Disease
Reinhold Schafer, Ph.D., Matthias E. Futschik, Ph.D., Wolfgang Kemmner, Ph.D., and Christine Sers, Ph.D.
Chapter 8 The Human Epigenome: Implications for the Understanding of Human Disease
Manel Esteller, Ph.D. and Maria Berdasco, Ph.D.
Chapter 9 The Human Proteome: Implications for the Understanding of Human Disease
Lance Liotta, Ph.D., Virginia Espina, Claudia Fredolini, Weidong Zhou, and Emanuel Petricoin
Chapter 10 Integrative Systems Biology: Implications for the Understanding of Human Disease
M. Michael Barmada, Ph.D. and David C. Whitcomb
PART III Principles and Practice of Molecular Pathology
Chapter 11 Pathology: The Clinical Description of Human Disease
William K. Funkhouser, M.D., Ph.D.
Chapter 12 Molecular Pathogenesis: The Biological Basis of Human Disease
William B. Coleman, Ph.D, and Gregory J. Tsongalis, Ph.D.
Chapter 13 Integration of Molecular and Cellular Pathogenesis
Jason H. Moore, Ph.D., and C. Harker Rhodes, M.D.
PART IV Molecular Pathology of Human Disease
Chapter 14 Molecular Basis of Cardiovascular Disease
Avrum I. Gotlieb, M.D.C.M. and Amber Chang Liu
Chapter 15 Molecular Basis of Hemostatic and Thrombotic Diseases
Nigel S. Key, M.D., and Alice Ma, M.D.
Chapter 16 Molecular Basis of Lymphoid and Myeloid Diseases
Dong-Er Zhang, Ph.D. and Joseph Biggs, Ph.D.
Chapter 17 Molecular Basis of Diseases of Immunity
David O. Beenhouwer, Ph.D.
Chapter 18 Molecular Basis of Pulmonary Disease
Dani S. Zander, M.D., and Carol Farver, M.D.Chapter
Chapter 19 Molecular Basis of Diseases of the Gastrointestinal TractAntonio Sepulveda, M.D., Ph.D. and Dara L. Aisner, M.D., Ph.D. Chapter 20 Molecular Basis of Liver DiseaseSatdarshan P. Singh Monga, M.D. and Jaideep Behari, M.D.Chapter 21 Molecular Basis of Diseases of the Exocrine PancreasMarkus M. Lerch, M.D. Chapter 22 Molecular Basis of Diseases of the Endocrine SystemMalcolm M. Martin, M.D., Arlene L. Martin, M.D., Alan L.Y. Pang, Ph.D., and Wai-Yee Chan, Ph.D. Chapter 23 Molecular Basis of Gynecologic Diseases Samuel Chi-ho Mok, Ph.D., Kwong-Kwok Wong, Ph.D., Karen Lu, M.D., Karl Munger, Ph.D., and Zoltan Nagymanyoki, Ph.D.Chapter 24 Molecular Pathogenesis of Diseases of the KidneyAmy K. Mottl, M.D., M.P.H., and Carla Nester, M.D., M.S.A.Chapter 25 Molecular Basis of Prostate DiseaseWilliam G. Nelson, M.D., Ph.D., Angelo M. De Marzo, M.D., Ph.D., and Carlise R. Bethel, M.D., Ph.D.Chapter 26 Molecular Basis of Breast DiseaseChristos Sotiriou, M.D., Ph.D., Natasha Snoj, Phuong Dinh, and Philippe BedardTranslational Research Unit, Jules Bordet Institute, Universite Libre de Bruxelles, Brussels, BelgiumChapter 27 Molecular Basis of Skin DiseaseJohn A. McGrath, Ph.D., and Vesarat Wessagowit, M.D., Ph.D. Chapter 28 Molecular Basis of Diseases of the Nervous SystemJoshua A. Sonnen, M.D., C. Dirk Keene, M.D., Robert F. Hevner, M.D., and Thomas J. Montine, M.D., Ph.D. PART V Practice of Molecular Medicine Chapter 29 Molecular Diagnosis of Human DiseaseGrant Bullock, M.D., Ph.D., and Lawrence M. Silverman, Ph.D. Chapter 30 Molecular Assessment of Human Disease in the Clinical LaboratoryGregory J. Tsongalis, Ph.D. and Joel A. Lefferts, M.D.Chapter 31 Pharmacogenomics and Personalized Medicine in the Treatment of Human Disease
Gregory J. Tsongalis, Ph.D. and Hong Kee Lee, Ph.D.