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Epigenetics
1st Edition, Volume 115 - August 12, 2014
Editor: Subhash C. Pandey
Language: English
Hardback ISBN:9780128013113
9 7 8 - 0 - 1 2 - 8 0 1 3 1 1 - 3
eBook ISBN:9780128014721
9 7 8 - 0 - 1 2 - 8 0 1 4 7 2 - 1
This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume co…Read more
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This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Epigenetics
This book looks at Epigeneticsin the light of the newest scholarly discoveries and insights
Neuroscientists, psychologists, neurologists
Preface
Chapter One: Environmental Alterations of Epigenetics Prior to the Birth
Abstract
1 Introduction
2 Manifestation of Environmental Factors
3 Mechanisms of Environmentally Induced Epigenetic Changes
4 Effect of Epigenetic Alterations on Neurodevelopment
Acknowledgments
Chapter Two: Transgenerational Epigenetics and Brain Disorders
Abstract
1 Introduction to Transgenerational Epigenetic Inheritance
2 Epigenetics and Epigenetic Processes
3 Evidence for Transgenerational Epigenetic Inheritance
4 Germline-Independent Epigenetic Inheritance
5 Germline-Dependent Epigenetic Transmission
6 Transgenerational Epigenetic Effects on Brain Disorders
7 Concluding Remarks
Acknowledgment
Chapter Three: The Epigenetic Landscape of Alcoholism
Abstract
1 Introduction
2 Epigenetic Regulation due to Histone Covalent Modifications
3 Epigenetic Regulation due to DNA Methylation
4 Genome-Wide Approaches to Understand the Basis of Alcoholism
5 Using Invertebrate Models to Study the Basis of Ethanol Phenotypes
6 Inheritance of a Drug Phenotype
7 Conclusions
Acknowledgments
Chapter Four: Epigenetic Regulatory Mechanisms in Stress-Induced Behavior
Abstract
1 Introduction
2 Stress-Induced Neural and Behavioral Changes in Adulthood and the Epigenetic Mechanisms Involved
3 DNA Methylation and Demethylation in Stress-Induced Neural and Behavioral Responses
4 Role of Noncoding RNAs in Epigenetic Regulation of Stress-Mediated Effects
5 Early-Life Stress-Induced Adult Onset Behavioral Disorders and the Epigenetic Mechanisms Involved
6 Conclusion
Acknowledgments
Chapter Five: Epigenetics of Schizophrenia: An Open and Shut Case
Abstract
1 Introduction
2 An Epigenetics Primer
3 Heterochromatization
4 Euchromatization
5 Schizophrenia and Epigenetics
6 Fulfilling the Promise of Epigenetics in Schizophrenia
7 Conclusion
Acknowledgments
Chapter Six: Epigenetic Mechanisms in Autism Spectrum Disorder
Abstract
1 Introduction
2 Molecular Aspects of Epigenetic Mechanisms
3 Genetic Defects with Epigenetic Implications
4 Epigenetic Dysregulation of ASD Candidate Genes
5 Environmental Model of Autism
6 Conclusions
Acknowledgments
Chapter Seven: MicroRNAs and Ethanol Toxicity
Abstract
1 Introduction
2 miRNAs and Their Biogenesis
3 Mechanisms of miRNA Function
4 miRNAs as Mediators of Ethanol Effects in Developing and Adult Tissues
5 miRNA-Mediated Transgenerational Inheritance of Information: A Novel Mechanism for Transgenerational Transfer of Epimutations?
6 Conclusions
Acknowledgments
Index
Contents of Recent Volumes
No. of pages: 344
Language: English
Edition: 1
Volume: 115
Published: August 12, 2014
Imprint: Academic Press
Hardback ISBN: 9780128013113
eBook ISBN: 9780128014721
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Subhash C. Pandey
Subhash C. Pandey is at University of Illinois at Chicago, USA