Drug-Induced Liver Disease
- Neil Kaplowitz
- Laurie DeLeve
This field has shown tremendous growth in recent years, primarily due to the recognition that drug-induced liver disease is the most common cause of liver failure and one of the major contributors to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the pharmaceutical industry and government settings. This book contains 4 new chapters on key topics in the area and provides a current and extensive review of the latest developments concerning the toxicology, pharmacology, genetics and immunology of drug-induced liver disease.
This reference is geared primarily towards medical specialists, including gastroenterologists, hepatologists, and pathologists, toxicologists, members of the pharmaceutical industry, and regulators. This book also provides an extensive review of mechanisms of toxicity and of drug safety and would be an excellent reference for students of toxicology, as a secondary audience.