Drug Discovery and Development

Technology in Transition

By

  • Raymond Hill, President, British Pharmacological Society, London, UK

Audience

Pharmacy students

Pharmacists working in the pharmaceutical industry

Lab technicians

 

Book information

  • Published: July 2012
  • Imprint: CHURCHILL LIVINGSTONE
  • ISBN: 978-0-7020-5316-0


Table of Contents

Contents

SECTION 1

INTRODUCTION AND BACKGROUND

1. The development of the pharmaceutical industry√ʬĬÉ

H P Rang

2. The nature of disease and the purpose of therapy√ʬĬÉ

H P Rang, R G Hill

3. Therapeutic modalities√ʬĬÉ

H P Rang, H LeVine, R G Hill

SECTION 2

DRUG DISCOVERY

4. The drug discovery process: general principles and some case histories√ʬĬÉ

H P Rang, R G Hill

5. Choosing the project√ʬĬÉ

H P Rang, R G Hill

6. Choosing the target√ʬĬÉ

H P Rang, R G Hill

7. The role of information, bioinformatics and genomics √ʬĬÉ

B Robson, R McBurney

8. High-throughput screening√ʬĬÉ

D Cronk

9. The role of medicinal chemistry in the drug discovery process√ʬĬÉ

P Beswick, A Naylor

10. DMPK optimization strategy in drug discovery√ʬĬÉ

P G Ballard, P Brassil, K H Bui, H Dolgos, C Petersson, A Tunek, P J H Webborn

11. Pharmacology: its role in drug discovery√ʬĬÉ

H P Rang

12. Biopharmaceuticals√ʬĬÉ

H LeVine

13. Scaffolds: Small globular proteins as antibody substitutes √ʬĬÉ

D Grabulovski, J Bertschinger

SECTION 3

DRUG DEVELOPMENT

14. Drug development: introduction

H P Rang, R G Hill

15. Assessing drug safety√ʬĬÉ

H P Rang, R G Hill

16. Pharmaceutical developmentT Lundqvist, S Bredenberg

17. Clinical Development - Present and Future√ʬĬÉ

C Keywood

18. Clinical imaging in drug development√ʬĬÉ

P M Matthews

19. Intellectual property in drug discovery and development√ʬĬÉ

P Grubb

20. Regulatory affairs√ʬĬÉ

I Hägglöf, Å Holmgren

21. Marketing the drug√ʬĬÉ

V L Lawton

SECTION 4

FACTS AND FIGURES

22. Drug discovery and development - facts and figures√ʬĬÉ

H P Rang, R G Hill