Store-Operated Calcium Channels book cover

Store-Operated Calcium Channels

Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful.


Scientists and researchers in biochemistry and molecular and cellular biology

Included in series
Current Topics in Membranes

Hardbound, 298 Pages

Published: August 2013

Imprint: Academic Press

ISBN: 978-0-12-407870-3


    1. Store-operated Orai channels: structure and function
      Murali Prakriya
    2. STIM-Orai Interactions that Control the CRAC Channel
      Aparna Gudlur, Yubin Zhou and Patrick G. Hogan
    3. Structure and Function of Endoplasmic Reticulum STIM Calcium Sensors
      Peter B. Stathopulos and Mitsuhiko Ikura
    4. On the Stoichiometry of Resting and Activated CRAC Channels
      Liangyi Chen and Tao Xu
    5. Alternative forms of the Store-operated Calcium Entry Mediators, STIM1 and Orai1
      James W. Putney
    6. The ARC Channel - An Endogenous Store-independent Orai Channel
      Jill L. Thompson, Olivier Mignen, and Trevor J. Shuttleworth
    7. Contribution and Regulation of TRPC Channels in Store-Operated Ca2+ Entry
      Kwong Tai Cheng, Hwei Ling Ong, Xibao Liu, and Indu S. Ambudkar
    8. Molecular Regulation of the Pore Component of CRAC Channels, Orai1
      Sonal Srikanth and Yousang Gwack
    9. Emerging Roles for Native Orai Ca2+ Channels in Cardiovascular Disease
      Brian Ruhle and Mohamed Trebak
    10. The Neglected CRAC Proteins: Orai2, Orai3 and STIM2
      Markus Hoth and Barbara A. Niemeyer


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