Correlative Light and Electron MIcroscopy book cover

Correlative Light and Electron MIcroscopy

The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM) has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM, including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM.

Audience

Researchers and students in cell, molecular and developmental biology

Included in series
Methods in Cell Biology

Hardbound, 460 Pages

Published: August 2012

Imprint: Academic Press

ISBN: 978-0-12-416026-2

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