Chagas Disease

Part A

Edited by

  • Herbert Tanowitz, Albert Einstein College of Medicine, Bronx, NY, USA
  • Louis M. Weiss, Professor of Medicine and Pathology, Albert Einstein College of Medicine of Yeshiva University, New York, U.S.A.

Edited by

  • Louis V Kirchhoff

This thematic volume provides authoritative, up-to-date reviews addressing recent advances as well as an overview for the research and clinical communities on the endemic infection of Chagas disease. Lead researchers discuss epidemiology and control measures as well as various diagnosis techniques, treatments, and therapies currently being used. The text includes a history of Chagas disease and an outlook for the next century.


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Researchers in parasitology, tropical medicine and entomology.


Book information

  • Published: August 2011
  • ISBN: 978-0-12-385863-4


"One is struck by the quality and scholarship of the various chapters and the obviously efficient editing."
"The policy of the editors of Advances in Parasitology to include reviews from any aspect of parasitology and the high standard of individual papers have resulted in this series of volumes becoming an indispensable source for students, teachers, and research workers."

Table of Contents

  1. Epidemiology of American trypanosomiasis (Chagas disease)
  2. Louis V. Kirchhoff, MD, MPH

  3. Acute and Congenital Chagas Diseases
  4. Caryn Bern, Diana Martin and Robert H. Gilman

  5. Cell Based Therapy in Chagas Disease
  6. Antonio C. Campos de Carvalho, Adriana B. Carvalho and Regina C. S. Goldenberg

  7. Targeting Trypanosoma cruzi sterol 14 alpha-demethylase
  8. Galina I. Lepesheva, Fernando Villalta, and Michael R. Waterman

  9. Experimental Chemotherapy and Approaches to Drug Discovery for Trypanosoma cruzi Infection
  10. Frederick S. Buckner

  11. Vaccine development against Trypanosoma cruzi and Chagas disease
  12. Juan C. Vázquez-Chagoyán, Shivali Gupta and Nisha Jain Garg

  13. Genetic Epidemiology of Chagas Disease
  14. Sarah Williams-Blangero, Ph.D, John L. VandeBerg, Ph.D2, John Blangero, Ph.D1, and Rodrigo Corrêa-Oliveira, Ph.D.

  15. Kissing Bugs. The Vectors of Chagas
  16. Lori Stevens, Patricia L. Dorn, Justin O. Schmidt, John H. Klotz, David Lucero and Stephen A. Klotz

  17. Advances in Imaging of Animal Models of Chagas Disease
  18. Linda A. Jelicks, PhD and Herbert B. Tanowitz, MD

  19. The Genome and its Implications
  20. Santuza M. Teixeira, Najib M. El-Sayed and Patrícia R. Araújo

  21. Genetic Techniques in Trypanosoma cruzi
  22. Martin C. Taylor, Huan Huang and John M. Kelly

  23. Nuclear structure of Trypanosoma cruzi
  24. Sergio Schenkman, Bruno dos Santos Pascoalino, Sheila C. Nardelli

  26. Samuel Goldenberg and Andrea Rodrigues Ávila

  27. The Role of Acidocalcisomes in the Stress Response of Trypanosoma cruzi
  28. Roberto Docampo*, Veronica Jimenez, Sharon King-Keller, Zhu-hong Li, and Silvia N.J. Moreno

  29. Signal transduction in Trypanosoma cruzi

          Huan Huang