Bioconjugate Techniques book cover

Bioconjugate Techniques

Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

Hardbound, 1186 pages

Published: August 2013

Imprint: Academic Press

ISBN: 978-0-12-382239-0


    1. Introduction to Bioconjugation
    2. Functional Targets for Bioconjugation
    3. The Reactions of Bioconjugation
    4. Zero-Length Crosslinkers
    5. Homobifunctional Crosslinkers
    6. Heterobifunctional Crosslinkers
    7. Trifunctional Crosslinkers
    8. Dendrimers and Dendrons
    9. Cross-Bridges and Cleavable Reagent Systems
    10. Fluorescent Probes
    11. (Strept)avidin - Biotin Systems
    12. Isotopic Labeling Techniques
    13. Silane Coupling Agents
    14. Microparticles and Nanoparticles
    15. Immobilization of Ligands on Chromatography Supports
    16. Buckyballs, Fullerenes, and Carbon Nanotubes
    17. Chemoselective Ligation; Bioorthogonal Reagents
    18. PEGylation & Synthetic Polymer Modification
    19. Vaccine and Immunogen Conjugates
    20. Antibody Modification and Conjugation
    21. Liposome Conjugates and Derivatives
    22. Enzyme Modification and Conjugation
    23. Nucleic Acid and Oligonucleotide Modification and Conjugation
    24. Bioconjugation for the Study of Protein Interactions


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