Table of ContentsReactive Species as Intracellular Messengers:L.-O. Klotz, K. Briviba, and H. Sies, Signalling by Singlet Oxygen in Biological Systems.D.R. Crawford, T. Suzuki, and K.J.A. Davies, Oxidant-modulated Gene Expression.H.H. Hassanain and P.J. Goldschmidt-Clermont, RAC, Superoxide, and Signal Transduction.S.K. Koliwad, A.K. Brzezinska, and S.J. Elliott, Redox Regulation of Ion Channels.J. Giron-Calle and H.J. Forman, Cell Ca2+ in Signal Transduction: Modulation in Oxidative Stress.G.L. Schieven, Introduction of Protein Tyrosine Phosphorylation by Oxidative Stress and its Implications.A.A. Deora and H.M. Lander, Regulation of Signal Transduction and Gene Expression by Reactive Nitrogen Species.Redox Sensitive Molecular Processes and Cellular Responses:P.A. Baeuerle, Reactive Oxygen Species as Costimulatory Signals of Cytokine-Induced NFkappaB Activation Pathways.T. Okamoto, T. Tetsuka, and T. Kawabe, Redox Regulation of Nuclear Factor kappa B.C.K. Sen, Oxidants and Antioxidants in Aptosis: Role of Bcl-2.V. Goossens, K. De Vos, D. Vercammen, M. Steemans, K. Vancompernolle, W. Fiers, P. Vandenabeele, and J. Grooten, Role of Reactive Oxygen Species in TNF Toxicity.S. Roy, C.K. Sen, A. Gozin, V. Andrieu, and C. Pasquier, Redox Regulation of Cell Adhesion Processes.H. Masutani, M. Ueno, S. Ueda, and J. Yodoi, Role of Thioredoxin and Redox Regulation in Oxidative Stress Response and Signalling.A.H. Schönthal, S. Mueller, and E. Cadenas, Redox Regulation of p21, Role of Reactive Oxygen and Nitrogen Species in Cell Cycle Progression.Clinical Implications of Redox Signaling and Antioxidant Therapy:H. Viita and S. YlÃ¤-Hertuala, Effect of Lipoxygenases on Gene Expression in Mammalian Cells.A. Azzi, Tocopherol in the Pathogenesis of Atherosclerosis: One Molecule, Several Functions.D.-Y. Jin and K.-T. Jeang, Peroxiredoxins in Cell Signaling and HIV Infection.J.S. Bertram, T. King, L. Fukishima, and F. Khachik, Enhanced Activity of an Oxidation Product of Lycopene Found in Tomato Products and Human Serum Relevant to Cancer Prevention.C. Bladier, J.B. de Haan, and I. Kola, Antioxidant Genes and Reactive Oxygen Species in Down's Syndrome.B.S. Kristal and B.P. Yu, Oxidant-mediated Repression of mtDNA Transcription.Y. Kajimoto, Y. Yamasaki, T. Matsuoka, H. Kaneto, and M. Hori, Suppression of the Insulin Gene Promoter Activity by Oxidative Stress.N. Maulik and D.K. Das, Redox Regulation of Ischemic Adaptation.W.C. Orr and R.S. Sohal, Oxidative Stress as a Governing Factor in Physiological Aging.W. Dröge, V. Hack, R. Breitkreutz, E. Holm, S. Holm, and R. Kinscherf, Antioxidants in Senescence and Wasting.Subject Index.