Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy - 1st Edition - ISBN: 9780128127377

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy, Volume 4

1st Edition

Series Volume Editors: Zhe-Sheng Chen Dong-Hua Yang
Hardcover ISBN: 9780128164358
Imprint: Academic Press
Published Date: 1st November 2018
Page Count: 300
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Table of Contents

1. EGFR and HER2 inhibitors as sensitizing agents for cancer chemotherapy
2. BCR-ABL inhibitors as sensitizing agents for cancer chemotherapy
3. VEGFR inhibitors as sensitizing agents for cancer chemotherapy
4. ALK inhibitors as sensitizing agents for cancer chemotherapy
5. JAK2 inhibitors as sensitizing agents for cancer chemotherapy
6. FLT3 inhibitors as sensitizing agents for cancer chemotherapy
7. BRAF inhibitors as sensitizing agents for cancer chemotherapy
8. Bruton kinase inhibitors as sensitizing agents for cancer chemotherapy


Description

Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new sensitizing agents to their research in clinical practice and in trials.

Key Features

  • Summarizes the sensitizing role of some tyrosine kinase inhibitors in existing research
  • Brings recent findings in several cancer types, both experimental and clinically, with a particular emphases on underlying biochemical, genetic, and molecular mechanisms
  • Provides an updated and comprehensive knowledge regarding the field of combinational cancer treatment

Readership

Cancer researchers; oncologists; pharmacists; graduate students on cancer studies


Details

No. of pages:
300
Language:
English
Copyright:
© Academic Press 2019
Published:
Imprint:
Academic Press
Hardcover ISBN:
9780128164358

Ratings and Reviews


About the Series Volume Editors

Zhe-Sheng Chen Series Volume Editor

Zhe-Sheng Chen opened the St. John’s University’s first cancer pharmacology laboratory. His research interest is multidrug resistance and its reversal, novel anti-cancer drug development. Chen serves as Editor of "African Journal of Pharmacy and Pharmacology"; Editor-in-Chief of “Journal of Cancer Research Updates" and "Journal of New Developments in Chemistry". He also serves as an Editorial Board member of 25 journals, an Ad Hoc reviewer of 180 journals, and a guest editor of "Current Pharmaceutical Biotechnology", "Cancer" and "Journal of International Medical Research". Chen has over 170 papers published, 6 book chapters, and 5 patents.

Affiliations and Expertise

Director, Institute for Biotechnology and Professor of Cancer Pharmacology, St. John’s University, USA

Dong-Hua Yang Series Volume Editor

Dong-Hua Yang is an Assistant Professor at St. John’s University College of Pharmacy and Health Sciences. She works in the fields of Cancer Biomarkers and Cancer Pharmacology. Before joining St. John’s, she was a Research Assistant Professor at Fox Chase Cancer Center, where she took charge of the Tissue Research Service at the Biosample Repository Core Facility. She is a leading expert in the field of immunohistochemistry (IHC) and IHC quantitative analysis. She applied IHC technology to study the molecular alterations of known and novel signaling pathways that regulate embryogenesis, organ morphogenesis and tumorigenesis. Yang leads the automatic quantitative analysis (AQUA) for immunohistochemistry and immunofluorescence assays for biomarker research. Yang is the regional editor of “Current Proteomics”, guest editor of “Frontiers of Pharmacology”, “Cancers” and “Molecules”, associate editor of “ Journal of Nutritional Therapeutics”, “Journal of Cancer Research Updates” and “Journal of Analytical Oncology”, ad hoc reviewer of 0ver 50 journals. Yang has over 70 papers and 4 book chapters published.

Affiliations and Expertise

Assistant Professor of Cancer biomarkers, St. John’s University College of Pharmacy and Health Sciences, USA