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Chemical Mediators of the Acute Inflammatory Reaction
International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences
1st Edition - January 1, 1972
Authors: M. Rocha E Silva, J. Garcia Leme
Editors: P. Alexander, Z. M. Bacq
eBook ISBN:
9 7 8 - 1 - 4 8 3 1 - 5 0 5 1 - 2
International Series of Monographs in Pure and Applied Biology, Modern Trends in Physiological Sciences, Volume 37: Chemical Mediators of the Acute Inflammatory Reaction traces… Read more
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International Series of Monographs in Pure and Applied Biology, Modern Trends in Physiological Sciences, Volume 37: Chemical Mediators of the Acute Inflammatory Reaction traces the history of investigation into the acute inflammatory reaction from the early observations in invertebrates to the experiments of therapeutic significance for humans. This book focuses on mediators that are accepted as being commonly involved in the inflammatory reaction, such as histamine, kinins, serotonin, prostaglandins, and permeability factors. The topics discussed include the phagocytic system and antibody production; factors which influence phagocytosis; measurement of the acute inflammatory reaction; and combined actions of mediators. The reaction to injury and manifestation of inflammation and biochemical aspects of anti-inflammatory drug reaction are also covered. This volume is beneficial to anatomists, biochemists, physiologists, immunologists, pathologists, pharmacologists, and clinicians interested in acute inflammatory reaction.
Preface
Acknowledgment
Chapter 1. Natural History of the Inflammatory Reaction
Earliest Theories on the Mechanism of Inflammation
Development of the Evidence
The Phagocytic System and Antibody Production
The Reticulo-Endothelial System (RES)
Factors which Influence Phagocytosis
Role of the Endothelial Cells
Role of Mast Cells
Conclusion
References
CHAPTER 2. Measurement of the Acute Inflammatory Reaction
Experimental Design
Peculiarities of the Methods Employed
Special Techniques
References
Chapter 3. Mediators of the Inflammatory Reaction
Mediators and "Immediators" of the Inflammatory Reaction
Histamine
Bradykinin and Related Kinins
High Molecular Permeability Factors
Combined Actions of Mediators
References
Chapter 4. Anti-Inflammatory Actions of Drugs
The Possible Mediators of Inflammation and Anti-Inflammatory Actions of Drugs
Effect of Anti-Inflammatory Drugs on Biogenesis and Releasing Systems of the Presumed Mediators
Reaction to Injury and Manifestation of Inflammation
Biochemical Aspects of Anti-Inflammatory Drug Reaction
Involvement of Nervous Structures in Inflammatory Reactions
Hormonal Influences on the Anti-Inflammatory Effects of Drugs
Conclusions
References
Author Index
Subject Index
Other Titles in the Division
- No. of pages: 276
- Language: English
- Edition: 1
- Published: January 1, 1972
- Imprint: Pergamon
- eBook ISBN: 9781483150512
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