Biophotonics for Medical Applications

1st Edition - June 24, 2015

Editor: Igor Meglinski

Hardback ISBN:

9 7 8 - 0 - 8 5 7 0 9 - 6 6 2 - 3

eBook ISBN:

9 7 8 - 0 - 8 5 7 0 9 - 6 7 4 - 6

Biophotonics for Medical Applications presents information on the interface between laser optics and cell biology/medicine. The book discusses the development and application of… Read more

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Biophotonics for Medical Applications presents information on the interface between laser optics and cell biology/medicine.

The book discusses the development and application of photonic techniques that aid the diagnosis and therapeutics of biological tissues in both healthy and diseased states. Chapters cover the fundamental technologies used in biophotonics and a wide range of therapeutic and diagnostic applications.

Part One: Materials, technologies, and processes
- 1: Multimodal diffuse optical imaging for biomedical applications
  - Abstract
  - 1.1 Introduction
  - 1.2 Optical imaging platforms for multimodal imaging
  - 1.3 Theoretical considerations
  - 1.4 Clinical applications of multimodal optical imaging
  - 1.5 Future perspectives in multimodal optical imaging
- 2: Photonic sensitive switchable materials
  - Abstract
  - 2.1 Introduction
  - 2.2 Photonic sensitive switchable materials
  - 2.3 Potential applications
  - 2.4 Conclusions and future trends
- 3: Optical fibres and sensors for biomedical applications
  - Abstract
  - 3.1 Optical fibres
  - 3.2 Optical fibre sensors
- 4: Laser processing of medical devices
  - Abstract
  - 4.1 Introduction
  - 4.2 Laser cutting
  - 4.3 Laser drilling
  - 4.4 Micromachining
  - 4.5 Surface texturing
  - 4.6 Conclusions
Part Two: Applications in therapeutics and diagnostics
- 5: Biomedicine with surface enhanced Raman scattering (SERS)
  - Abstract
  - 5.1 Introduction
  - 5.2 Surface enhanced Raman scattering
  - 5.3 Theory of surface enhanced Raman scattering
  - 5.4 SERS substrates
  - 5.5 Bioimaging and sensing with SERS
  - 5.6 Biomedical applications of SERS
  - 5.7 Prospects of the technology
- 6: Optical cancer screening
  - Abstract
  - Acknowledgments
  - 6.1 Introduction: screening cancer using light
  - 6.2 Spectroscopic methods for cancer detection
  - 6.3 NIR polarization imaging of prostate cancer tissue enhanced by receptor-targeting contrast agents
  - 6.4 Detection and three-dimensional (3D) localization of cancerous prostate tissue
  - 6.5 Outlook and conclusion
- 7: Biophotonics for assessing breast cancer
  - Abstract
  - Acknowledgments
  - 7.1 Introduction
  - 7.2 Optical biopsy: Assessing breast cancer at the microscopic scale
  - 7.3 Optical mammography: Assessing breast cancer at the macroscopic scale
  - 7.4 Conclusion
- 8: Label-free optical imaging of live cells
  - Abstract
  - 8.1 Introduction
  - 8.2 Optical microscopy of live cells, resolution and contrast
  - 8.3 Raman microscopic imaging of live cells
  - 8.4 FTIR imaging of live cells
  - 8.5 Conclusions and outlook
- 9: Biophotonics for blood analysis
  - Abstract
  - 9.1 Introduction
  - 9.2 Optical inference and control of blood physiology
  - 9.3 Blood flow analysis by optical means
  - 9.4 Conclusions
- 10: Biophotonics for tissue oxygenation analysis
  - Abstract
  - 10.1 Introduction
  - 10.2 Fundamentals of tissue oxygenation analysis by using optical measurement
  - 10.3 The clinical applications of the near-infrared oxygenation monitoring
- 11: Encapsulated biosensors for advanced tissue diagnostics
  - Abstract
  - 11.1 Introduction
  - 11.2 Microcapsules fabrication
  - 11.3 Conclusion
- 12: Optical methods for assessing skin flap survival
  - Abstract
  - 12.1 Introduction
  - 12.2 Methods
  - 12.3 Future trends
  - 12.4 Sources of further information
- 13: Early optical diagnosis of pressure ulcers
  - Abstract
  - 13.1 Introduction
  - 13.2 Clinical diagnostics of pressure ulcers
  - 13.3 Healing pressure ulcers
  - 13.4 Commercially available biophotonic equipment applicable for pressure ulcer diagnostics and treatment
  - 13.5 Summary
Index