DNA Topoisomearases: Biochemistry and Molecular Biology book cover

DNA Topoisomearases: Biochemistry and Molecular Biology

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

Audience
Pharmacologists, cancer researchers, biochemists, microbiologists, cell biologists.

Included in series
Advances in Pharmacology

Hardbound, 320 Pages

Published: September 1994

Imprint: Academic Press

ISBN: 978-0-12-032929-8

Reviews

  • "The book provides superb reading material which chemists and pharmacologists interested in the area of chemotherapy will surely enjoy reading."
    Praise for the Serial, --JOURNAL OF PHARMACEUTICAL SCIENCES

Contents

  • J.C. Wang, DNA Topoisomerases as Targets of Therapeutics: An Overview.Y.-C. Tse-Dinh, Biochemistry of Bacterial Type I DNA Topoisomerases.R. Menzel and M. Gellert, The Biochemistry and Biology of DNA Gyrase.J.J. Champoux, Mechanism of Catalysis by Eukaryotic DNA Topoisomerase I.A.H. Andersen, J.Q. Svejstrup, and O. Westergaard, The DNA Binding, Cleavage, and Religation Reactions of Eukaryotic Topoisomerases I and II.J.L. Nitiss, Roles of DNA Topoisomerases in Chromosomal Replication and Segregation.M. Drolet, H.-Y. Wu., and L.F. Liu, Roles of DNA Topoisomerases in Transcription.H. Ikeda, DNA Topoisomerase-Mediated Illegitimate Recombination.J. Hwang and C.-L. Hwong,Cellular Regulation of Mammalian DNA Topoisomerases.T.-s. Hsieh, M.P. Lee, and S.D. Brown, Structure of Eurkaryotic Type I DNA Topoisomerase.W.M. Huang, Type II DNA Topoisomerase Genes.H.C. Neu, Major Advances in Antibacterial Quinolone Therapy.K. Drlica and B. Kreiswirth, 4-Quinolones and the Physiology of DNA Gyrase.L.L. Shen, Molecular Mechanisms of DNA Gyrase Inhibition by Quinolone Antibacterials.References.Subject Index.

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