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Mpox Information Center

2023年7月25日

Monkeypox microscopic image

Elsevier's free resource for clinical information and research on the mpox virus

Caption: Monkeypox virus (© istock.com/kontekbrothers)

Note: In line with WHO ending the Public Health Emergency of International Concern for Mpox on 11 May 2023, Mpox-related content published up until July 2023 will remain freely available.

Mpox — a zoonotic viral disease endemic to western and central Africa — has become a public health emergency of international concern. It's spread via direct contact, respiratory droplets, and contaminated materials and surfaces. Mpox is caused by the mpox virus, which belongs to the Orthopoxvirus genus of the Poxviridae family; other members of Orthopoxvirus include variola virus (which causes smallpox), vaccinia virus (used in smallpox vaccines), cowpox virus, and various other animal poxviruses. Mpox classically presents with rash, fever, lymphadenopathy, and a clinical course similar to that of smallpox but milder; case fatality rates of 3% to 6% have been reported in African countries where the disease is endemic, and Brazil, Spain and India have reported the first mpox deaths(新しいタブ/ウィンドウで開く) outside of endemic countries.

This information, from ClinicalKey, is available in Elsevier's Mpox Healthcare Hub(新しいタブ/ウィンドウで開く) — one of various resources we are offering here for clinicians, researchers and public health officials.

Clinical information

To help healthcare professionals respond to the outbreak, Elsevier has created the Mpox Healthcare Hub. Here you will find evidence-based clinical resources, including clinical overviews, patient education and drug monographs.

Research

Elsevier and the Lancet Mpox content collections

We identified Mpox-related articles from Elsevier, Cell Press and The Lancet, along with Mpox-related book chapters, and made them freely available on ScienceDirect(新しいタブ/ウィンドウで開く) and via The Lancet(新しいタブ/ウィンドウで開く) for the duration of the crisis. We also made this collection available as a machine-readable corpus to enable advanced discovery methods and identification of patterns and relationships in data (text and data mining).

Additionally, we collaborated with the World Health Organization (WHO) and the National Library of Medicine (NLM) to make this content rapidly and freely available to global research and health communities as well as the general public from Pubmed Central (PMC) at PMC Mpox Collection(新しいタブ/ウィンドウで開く), including for text and data mining via the PMC Open Access Subset(新しいタブ/ウィンドウで開く).

In line with WHO ending the Public Health Emergency of International Concern for Mpox on 11 May 2023, Mpox-related content published up until July 2023 will remain freely available. This content is available both via Elsevier’s websites, as well as via PMC whom we allow to retain this content in perpetuity under the terms of the original licenses.

Here are some example articles:

Early-stage research on SSRN’s Mpox Hub

Rapidly evolving healthcare emergencies necessitate the quick dissemination of research. SSRN(新しいタブ/ウィンドウで開く) — Elsevier’s platform for the rapid worldwide dissemination of early-stage research — is committed to making authors' Mpox-related preprints available immediately. Their Mpox Hub(新しいタブ/ウィンドウで開く) provides a curated view into new early-stage research to help researchers, public health authorities, clinicians and the public understand, contain, navigate, and manage the current outbreak. By presenting insights from many disciplines, they hope to inform the ongoing conversation about the Mpox virus.

Research on SSRN is free to download and upload. It is important to note that these preprints have not benefited from the pivotal role of the peer-review process, which validates and improves the quality of final published journal articles.

Monkeypox on a dish

Mpox datasets on Mendeley Data

We have selected datasets indexed by the Data Monitor search engine on the 2022 Mpox outbreak to make it easier to find potentially relevant datasets for this topic.

Public health

Here, you will find guidance and commentary from experts along with official guidance from major health organizations. For research on public health, see the research section of this article.

What do HIV and COVID-19 have to do with Mpox?

As Mpox spreads, what lessons can we apply from the last two pandemics? Elsevier author Prof Rodney Rohde of Texas State University — a microbiologist and infectious disease expert — weighs in. Read his editorial

Rodney Rohde at TSU Lab

Lancet podcast

What’s happening with mpox in Africa? Why wasn’t Mpox tackled when we had the chance? What will the PHEIC declaration change? For this episode of The Lancet Voice(新しいタブ/ウィンドウで開く), Prof Yap Boum, Epicentre Representative for Africa, the research arm of Medecins sans Frontières, joins Gavin Cleaver and guest host Dr Miriam Lewis Sabin, North American Executive Editor of The Lancet.

The Lancet Voice logo