The Enzymes

Aim & scope

THE ENZYMES is a Serial which was founded in 1970 by the Nobel Prize winner Paul D. Boyer, who acted as a Serial Editor for many years. Since its conception, the series has covered ground-breaking research in enzyme structure, function, and control by providing updates and innovative information in key areas of research, becoming a highly valued reference text and covering a rather large number of enzymes in each of the more than 50 volumes published to date. Biochemists, chemists, cell biologists, molecular biologists, and many other scientists benefitted and will benefit from this thematic series which was thereafter guest edited by other leaders in the field. Since 2023, Prof. Claudiu T. Supuran from University of Florence, Italy, became Serial Editor and the first volumes edited under his leadership were published in 2024.

The goal of this book series is to provide a reference for years to come, written by world renowned expert investigators studying particular enzymes that have key biological roles in many different biological functions and diseases such as obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular and mood-related manifestations, infections, and more are being uncovered at an expanding rate. Expansion of our understanding of enzymes and modulating their function with inhibitors and activators affords in health and disease the opportunity for novel therapeutics. This Serial will continue to offer a thorough overview of enzymes, spanning biochemical and structural features, pharmacology, and biomedical/biotechnological/environmental applications. Each book will continue to follow this general outline used also in the previously published volumes:

(i) structure and function of an enzyme family/class based on the latest genomic data; (ii) physiological/pathological role(s); (iii) classes of inhibitors and activators and their design; (iv) clinically applied agents and/or compounds that are in clinical development; (v) other biomedical and biotechnological applications; (vi) new techniques/technologies developed for investigating enzymes and their function; (vii) challenges to study a certain enzyme or class of enzymes, especially from organisms difficult to cultivate in laboratory (extremophilic bacteria, archaea, pathogens/organisms which possess many life stages and complicated life cycles, etc).

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