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Profile

Dorothee Dormann

Dorothee Dormann

Johannes Gutenberg University, Mainz, Germany

Dorothee Dormann is Full Professor of Molecular Cell Biology at Johannes Gutenberg University Mainz and Adjunct Director at the Institute of Molecular Biology (IMB) Mainz, Germany. She studied Biochemistry in Tübingen, Germany, and obtained a Ph.D. in Cell Biology/Immunology from the Rockefeller University, New York. After postdoctoral work with Christian Haass at LMU Munich, she headed an independent research group at the BioMedical Center in Munich from 2014 - 2021. In 2021, she moved her laboratory to JGU and IMB Mainz. Her research focuses on the molecular mechanisms of neurodegenerative disorders, in particular how mislocalization and aggregation of RNA-binding proteins occur in amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease. Her lab studies nucleocytoplasmic transport, phase separation and post-translational modifications of disease-linked RNA-binding proteins and how these mechanisms are disturbed in disease.