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| PRINCIPLES OF LABORATORY ANIMAL SCIENCE, REVISED EDITION
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 A contribution to the humane use and care of animals and to the quality of experimental results
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Edited By
L. F. van Zutphen, Utrecht University, Department of Veterinary Science, Utrecht, The Netherlands
V. Baumans
A. C. Beynen, Department of Laboratory Animal Science, Utrecht University, Utrecht, The Netherlands
Description
The welfare of laboratory animals, as well as the ethical issues involved in the humane use of animals for scientific purposes, are discussed
in this new revised edition. Information is included on the biology and husbandry of animal models; on behavior, stress and well-being;
genetic and microbiological standardization; health monitoring; anaesthesiology; animal alternatives; ethics. This book addresses all
of the aspects that scientists need to know when considering the design of an animal experiment. Replacement, reduction and refinement
of animal experiments are the guiding principles for its contents.
Contents
Preface. Contributors. Introduction (L.F.M. van Zutphen). Legislation and animal experimentation (P.C.M. de Greeve, J. Hampson, L.F.M.
van Zutphen). Biology and husbandry of laboratory animals (R. Havenaar, J.C. Meijer, D.B. Morton, J. Ritskes-Hoitinga, P. Zwart). Behaviour,
stress and well-being (J.M. Koolhaas, V. Baumans, H.J.M. Blom, D. von Holst, P.J.A. Timmermans, P.R. Wiepkema). Standardization of animal
experimentation (A.C. Beynen, K. Gartner, L.F.M. van Zutphen). Nutrition and experimental results (A.C. Beynen, M.E. Coates). Genetic
standardization (L.F.M. van Zutphen, H.J. Hedrich, H.A. van Lith, J.B. Prins). Microbiological standardization (R. Boot, J.P. Koopman,
I. Kunstyl). Diseases of laboratory animals (J.E. van Dijk, H. van Herck, M.C. Bosland). Animal models (A.C. Beynen, J. Hau). Phases
in an animal experiment (A.C. Beynen, M.F.W. Festing). Design of animal experiments (A.C. Beynen, M.F.W. Festing, M.A.J. van Montfort).
Organization and management of animal experiments (A.E.J.M. van den Bogaard, R. Fosse, R.G.M. ten Berg, J.T.W.A. Strik). Recognition
of pain and distress ((V. Baumans, P.F. Brain). Anaesthesia, analgesia and euthanasia (L.J. Hellebrekers, L.H.D.J. Booij, P. Flecknell).
Experimental procedures (V. Baumans, R. Remie, H.J. Hackbarth, A. Timmerman). Reduction and replacement concepts in animal experimentation
(J. Nab, M. Balls, J.B.F. van der Valk, C.F.M. Hendriksen). Ethical aspects of animal experimentation (Tj. de Cock Buning, F.R. Heeger,
H. Verhoog). Annex. Index.
Bibliographic & ordering Information
Hardbound, 428 pages, publication date: MAY-2001
ISBN-13: 978-0-444-50612-2
ISBN-10: 0-444-50612-8
Imprint: ELSEVIER
062/649
Last update: 25 Aug 2008
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