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 To order this title, and for more information, click here
By
F Pietra, Universita di Trento
Trento
Italy
J.E. Baldwin
Robert M. Williams, Department of Chemistry, Colorado State University, Fort Collins, Colorado, 80523, USA
Included in series
Tetrahedron Organic Chemistry Series,
Tetrahedron Organic Chemistry Series, 21
Description
This, the most recent contribution to the Tetrahedron Organic Chemistry series, provides an integrated evaluation of the diversity of
natural products in relation to biodiversity. The ongoing exploitation of biological resources, while maintaining an effective equilibrium
on Earth, depends much on the conservation of biodiversity. To this end, parts one and two focus on biodiversity from all viewpoints,
while explaining the link with natural products. The third section concentrates on the molecular-shape level, as a link to ecosystem
and biodiversity, while the fourth section tackles actual functionalization, as a link to biodiversity at species level. Part five addresses
the diversification of these resources from biotechnology and chemical technology, while the final part is concerned with maintaining
natural product diversity on Earth.
Audience
Primarily addressed to professionals in life sciences (ecologists and biotechnologists). Biotechnologists include people in drug discovery and natural products chemistry.
Contents
Part I. The concept of biodiversity.
Defining Biodiversity.
Biodiversity at species level. Biodiversity at higher taxonomic levels.
Biodiversity at genetic level. Biodiversity at ecosystem level.
The Course of Biodiversity.
Part II. The relationship between
biodiversity and natural product diversity.
Taxonomy, Phylogeny, and Natural Products.
The Problem of Unculturable Species.
Natural Product Diversity: at which rank?
The molecular rank. The taxonomic and ecological rank.
Part III. Natural product diversity
at ecosystem level.
Terrestrial and Freshwater Biomes.
Tropical rain forest, grassland and savanna, scrub and deciduous forest.
American tropical and subtropical land. African tropical and subtropical land. Eastern tropical and subtropical land. Temperate grassland,
deciduous forest, and chaparral. The taiga and the tundra.
The Oceans.
Zonation of the seas and oceans. Indo-Pacific. Caribbean.
Panamanian. Mediterranean. North Pacific. South Pacific
North Atlantic. South Atlantic. Zealandic. Arctic. Antarctic. Internal seas.
The Widespread Distribution of Natural Products.
The widespread distribution of natural products on land. The widespread distribution
of natural products in the oceans. Found both on land and in the sea.
Terrestrial vs Marine Natural Product Diversity.
Life
under Extreme Conditions.
Graphic Analysis of the Skeletal Diversity and Complexity
of Natural Products.
Part IV. Natural
product diversity at functional level.
Signaling, Defensive, and Environmentally Relevant Metabolites.
Recruiting, alarming,
and growth stimulating agents. Antifeedant and antimicrobial agents. Toxins and environmentally noxious metabolites. Messengers of biodiversity.
Mediators of signals.
Exploiting Natural Product Diversity.
Food, food additives, and food processing from land and the oceans.
Commercial natural drugs and folk medicines. Natural products, derivatives, and extracts in development as drugs. Fragrances and cosmetics.
Technological compounds and laboratory tools. Drugs of abuse.
Part V. Biotechnology and chemical synthesis of natural products.
The
Role of Biotechnology.
Biotechnology and natural products. Biocatalysis.
The Role of Chemical Synthesis.
Part VI. Threatening
and management of natural product diversity.
Threatening Natural Product Diversity.
Fossil molecules and past natural product
diversity. Endangered natural products. Threats from farming and urbanization. Threats from the introduction of alien species. Threats
from toxicity, ecotoxicity, and climate changes following industrialization. Threats from biotechnology. A tentative list of endangered
natural products. Our biased view?
Management of Natural Product Diversity.
Preserving natural product diversity through the
management of living species. Preserving natural product diversity through collections and gene banks.
Bibliographic & ordering Information
Hardbound, 366 pages, publication date: MAY-2002
ISBN-13: 978-0-08-043707-1
ISBN-10: 0-08-043707-9
Imprint: PERGAMON
Price: Order form
GBP 105
EUR 149
USD 190
Paperback, 366 pages, publication date: MAY-2002
ISBN-13: 978-0-08-043706-4
ISBN-10: 0-08-043706-0
Imprint: PERGAMON
Price: Order form
EUR 52.95
USD 66.95
GBP 37.99
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Last update: 29 Aug 2008
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