Recent advances in clinical management and uses of conventional and novel therapies
Guide for Authors
Update on Cancer Therapeutics publishes solicited and unsolicited review articles which focus on recent advances in the understanding
of anti-cancer drugs, biological agents and multi-disciplinary management of specific malignancies. The journal also publishes themed
article collections, commentaries on recently published clinical trials, and clinical trial protocols. Authors who wish to submit an
unsolicited review to Update on Cancer Therapeutics are requested to send a short synopsis of their proposed review article
(along with references to 3 publications of their prior work relating to the proposed review article) to the Editorial Office via email
at UCT@elsevier.com.
Submission checklist
Please ensure that the following items are present prior to
sending the manuscript to the Journal Editors for review: • One Author designated as corresponding Author: • E-mail
address • Full postal address • Telephone and fax numbers • All necessary files have been included •
Keywords (up to 10) • All figure captions • All tables (including title, description, footnotes)
Further considerations:
• Manuscript has been "spellchecked" • References are in the correct format for this journal • All references
mentioned in the Reference list are cited in the text, and vice versa • Permission has been obtained for use of copyrighted
material from other sources (including the Web)
Submission to this journal proceeds totally online. Via the homepage of this journal (http://ees.elsevier.com/uct)
you will be guided stepwise through the creation and uploading of the various files. The system automatically converts source files to
a single Adobe Acrobat PDF version of the article, which is used in the peer-review process. Please note that even though manuscript
source files are converted to PDF at submission for the review process, these source files are needed for further processing after acceptance.
All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail and via the author's
homepage, removing the need for a hard-copy paper trail.
If you have any difficulties submitting your manuscript online please contact
the Editorial Office for Update on Cancer Therapeutics at UCT@elsevier.com.
Prior to Submission
Update on Cancer Therapeutics will consider manuscripts prepared according to the guidelines adopted by the International
Committee of Medical Journal Editors ("Uniform requirements for manuscripts submitted to biomedical journals", available as a PDF from
www.icmje.org). Authors are advised to read these guidelines.
Previous
Publication Submission of an article implies that the work described has not been published previously (except in the form of
an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that
its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and
that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without the written consent
of the Publisher.
Ethics
Work on human beings that is submitted to Update on Cancer Therapeutics should comply with the
principles laid down in the Declaration of Helsinki; Recommendations guiding physicians in biomedical research involving human subjects.
Adopted by the 18th World Medical Assembly, Helsinki, Finland, June 1964, amended by the 29th World Medical Assembly, Tokyo, Japan, October
1975, the 35th World Medical Assembly, Venice, Italy, October 1983, and the 41st World Medical Assembly, Hong Kong, September 1989. The
manuscript should contain a statement that the work has been approved by the appropriate ethical committees related to the institution(s)
in which it was performed and that subjects gave informed consent to the work. Studies involving experiments with animals must state
that their care was in accordance with institution guidelines. Patients' and volunteers' names, initials, and hospital numbers should
not be used.
Conflict of Interest At the end of text, under a subheading "Conflict of interest statement" all authors
must disclose any financial and personal relationships with other people or organisations that could inappropriately influence (bias)
their work.
Role of the Funding Source All sources of funding should be declared as an acknowledgment at the end of
the text.
Authorship and Acknowledgments All authors should have made substantial contributions to all of the following:
(1) the conception and design of the study, or acquisition of data, or analysis and interpretation of data, (2) drafting the article
or revising it critically for important intellectual content, (3) final approval of the version to be submitted.
All contributors
who do not meet the criteria for authorship as defined above should be listed in an acknowledgements section. Examples of those who might
be acknowledged include a person who provided purely technical help, writing assistance, or a department chair who provided only general
support. Authors should disclose whether they had any writing assistance and identify the entity that paid for this assistance.
Copyright Upon acceptance of an article, Authors will be asked to transfer copyright (for more information on copyright see www.elsevier.com/authors
). This transfer will ensure the widest possible dissemination of information. A letter will be sent to the corresponding Author confirming
receipt of the manuscript. A form facilitating transfer of copyright will be provided. If excerpts from other copyrighted works are
included, the Author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has
preprinted forms for use by Authors in these cases: contact Elsevier's Rights Department, Philadelphia, PA, USA: phone (+1) 215 239 3804,
fax (+1) 215 239 3805, e-mail healthpermissions@elsevier.com. Requests may also be completed on-line via the Elsevier
homepage (http://www.elsevier.com/locate/permissions) .
Funding body agreements and policies Elsevier
has established agreements and developed policies to allow authors who publish in Elsevier journals to comply with potential manuscript
archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please
visit http://www.elsevier.com/fundingbodies.
Authors' Rights As an author you (or your employer or institution)
may do the following: • make copies (print or electronic) of the article for your own personal use, including for your own classroom
teaching use • make copies and distribute such copies (including through e-mail) of the article to research colleagues, for
the personal use by such colleagues (but not commercially or systematically, e.g., via an e-mail list or list server) • post
a pre-print version of the article on Internet websites including electronic pre-print servers, and to retain indefinitely such version
on such servers or sites • post a revised personal version of the final text of the article (to reflect changes made in the
peer review and editing process) on your personal or institutional website or server, with a link to the journal homepage (on http://www.elsevier.com)
• present the article at a meeting or conference and to distribute copies of the article to the delegates attending such a meeting
• for your employer, if the article is a 'work for hire', made within the scope of your employment, your employer may use all
or part of the information in the article for other intra-company use (e.g., training) • retain patent and trademark rights
and rights to any processes or procedure described in the article • include the article in full or in part in a thesis or dissertation
(provided that this is not to be published commercially) • use the article or any part thereof in a printed compilation of your
works, such as collected writings or lecture notes (subsequent to publication of your article in the journal) • prepare other
derivative works, to extend the article into book-length form, or to otherwise re-use portions or excerpts in other works, with full
acknowledgement of its original publication in the journal
General Points
We accept most wordprocessing formats, but Word,
WordPerfect or LaTeX is preferred. Always keep a backup copy of the electronic file for reference and safety. Save your files using the
default extension of the program used.
It is important that the file be saved in the native format of the wordprocessor used. The
text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and
replaced on processing the article. In particular, do not use the wordprocessor's options to justify text or to hyphenate words. However,
do use bold face, italics, subscripts, superscripts etc. Do not embed "graphically designed" equations or tables, but prepare these using
the wordprocessor's facility. When preparing tables, if you are using a table grid, use only one grid for each individual table and not
a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very
similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: www.elsevier.com/authors ).
Do not import the figures into the text file but, instead, indicate their approximate locations directly in the electronic text and on
the manuscript. See also the section on Preparation of electronic illustrations.
To avoid unnecessary errors you are strongly advised
to use the "spellchecker" function of your wordprocessor.
Presentation of Manuscript
Please write your text in good English
(American or British usage is accepted, but not a mixture of these). Italics are not to be used for expressions of Latin origin, for
example, in vivo, et al., per se. Use decimal points (not commas); use a space for thousands (10 000 and above).
Title: Concise and informative. Titles are often used in information-retrieval systems.
Avoid abbreviations and formulae where possible.
Author names and affiliations: Where the family name may be ambiguous (e.g.,
a double name), please indicate this clearly. Present the Authors' affiliation addresses (where the actual work was done) below the names.
Indicate all affiliations with a lower-case superscript letter immediately after the Author's name and in front of the appropriate address.
Provide the full postal address of each affiliation, including the country name, and, if available, the e-mail address of each Author.
Corresponding Author: Clearly indicate who is willing to handle correspondence at all stages of refereeing and publication,
also post-publication. Ensure that telephone and fax numbers (with country and area code) are provided in addition to the e-mail address
and the complete postal address.
Present/permanent address: If an Author has moved since the work described in the article
was done, or was visiting at the time, a "Present address"' (or "Permanent address") may be indicated as a footnote to that Author's
name. The address at which the Author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals
are used for such footnotes.
Abstract: A concise and factual abstract is required (maximum length 250 words). The abstract
should briefly state the purpose of the review, the results and the major conclusions. An abstract is often presented separate from
the article, so it must be able to stand alone.
Keywords: Immediately after the abstract provide a maximum of ten keywords,
to be chosen from the Medical Subject Headings from Index Medicus. These keywords will be used for indexing purposes.
Abbreviations: Define abbreviations that are not standard in this field at their first occurrence in the article: in the abstract but also in the
main text after it. Ensure consistency of abbreviations throughout the article.
Text: This should start on the third page
and should be subdivided into appropriate sections.
References: Responsibility for the accuracy of bibliographic citations
lies entirely with the authors.
Please ensure that every reference cited in the text is also present in the reference list (and vice
versa). Any references cited in the abstract must be given in full. "Unpublished data" and "Personal communications" are not allowed.
As an alternative, say in the text, for example, '(data not shown)' or '(Dr F.G. Tomlin, Karolinska Institute)'. Citation of a reference
as "in press" implies that the item has been accepted for publication and a copy of the title page of the relevant article must be submitted.
Indicate references by superscript numbers in the text. The actual authors can be referred to, but the reference numbers must always
be given.
Number the references (numbers in square brackets) in the reference list in the order in which they appear in the text.
Examples: Reference to a journal publication: 1. Van der Geer J, Hanraads JAJ, Lupton RA. The art of writing a
scientific article. J Sci Commun 2000; 163 : 51-9.
Reference to a book: 2. Strunk Jr W, White EB. The elements of style. 3rd ed.
New York: Macmillan; 1979.
Reference to a chapter in an edited book: 3. Mettam GR, Adams LB. How to prepare an electronic version
of your article. In: Jones BS, Smith RZ, editors. Introduction to the electronic age, New York: E-Publishing Inc; 1999, p. 281-304
For
more than 6 authors that first 6 should be listed followed by "et al". For further details you are referred to "Uniform Requirements
for Manuscripts submitted to Biomedical Journals" (J Am Med Assoc 1997; 277 : 927-934) (see also http://www.nlm.nih.gov/tsd/serials/terms_cond.html)
.
Figure Captions, Tables, Figures and Schemes
Present these, in this order, at the end of the article. They are described
in more detail below. High-resolution graphics files must always be provided separate from the main text file (see Preparation of illustrations).
Footnotes Footnotes should be used sparingly. Number them consecutively throughout the article, using superscript Arabic
numbers. Many wordprocessors build footnotes into the text, and this feature may be used. Should this not be the case, indicate the position
of footnotes in the text and present the footnotes themselves on a separate sheet at the end of the article. Do not include footnotes
in the Reference list.
Table footnotes Indicate each footnote in a table with a superscript lowercase letter.
Tables Number tables consecutively in accordance with their appearance in the text. Place footnotes to tables below the table body and indicate
them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that the data presented in
tables do not duplicate results described elsewhere in the article.
Nomenclature and Units Follow internationally accepted
rules and conventions: use the international system of units (SI). If other quantities are mentioned, give their equivalent in SI.
Preparation
of Electronic Illustrations • Make sure you use uniform lettering and sizing of your original artwork. • Save text
in illustrations as "graphics" or enclose the font. • Only use the following fonts in your illustrations: Arial, Courier, Helvetica,
Times, Symbol. • Number the illustrations according to their sequence in the text. • Use a logical naming convention
for your artwork files. • Provide all illustrations as separate files and as hardcopy printouts on separate sheets. •
Provide captions to illustrations separately. • Produce images near to the desired size of the printed version.
A detailed guide
on electronic artwork is available on our website: www.elsevier.com/authors You are urged to visit this site; some
excerpts from the detailed information are given here.
Formats Regardless of the application used, when your electronic
artwork is finalised, please "save as" or convert the images to one of the following formats (Note the resolution requirements for line
drawings, halftones, and line/halftone combinations given below.): EPS: Vector drawings. Embed the font or save the text as "graphics".
TIFF: Colour or greyscale photographs (halftones): always use a minimum of 300 dpi. TIFF: Bitmapped line drawings: use a minimum
of 1000 dpi. TIFF: Combinations bitmapped line/half-tone (colour or greyscale): a minimum of 500 dpi is required. DOC, XLS or
PPT: If your electronic artwork is created in any of these Microsoft Office applications please supply "as is". Please do not: •
Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document; • Supply files that are optimised for
screen use (like GIF, BMP, PICT, WPG); the resolution is too low; • Supply files that are too low in resolution; •
Submit graphics that are disproportionately large for the content.
If, together with your accepted article, you submit usable colour
figures then Elsevier will ensure, at no additional charge, that these figures will appear in colour on the Web (e.g., ScienceDirect
and other sites).
Captions Ensure that each illustration has a caption. Supply captions separately, not attached to
the figure. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the
illustrations themselves to a minimum but explain all symbols and abbreviations used.
Line drawings The lettering and
symbols, as well as other details, should have proportionate dimensions, so as not to become illegible or unclear after possible reduction;
in general, the figures should be designed for a reduction factor of two to three. The degree of reduction will be determined by the
Publisher. Illustrations will not be enlarged. Consider the page format of the journal when designing the illustrations. Do not use
any type of shading on computer-generated illustrations.
Photographs (halftones) Remove non-essential areas of a photograph.
Do not mount photographs unless they form part of a composite figure. Where necessary, insert a scale bar in the illustration (not below
it), as opposed to giving a magnification factor in the caption.
Note that photocopies of photographs are not acceptable.
Preparation
of supplementary data Elsevier accepts electronic supplementary material to support and enhance your scientific research. Supplementary
files offer the Author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images,
background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of
your article in Elsevier Web products, including ScienceDirect: http://www.sciencedirect.com . In order to ensure that
your submitted material is directly usable, please ensure that data is provided in one of our recommended file formats. Authors should
submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For more
detailed instructions please visit our artwork instruction pages at www.elsevier.com/authors
Funding body agreements
and policies
Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published
by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more
about existing agreements and policies please visit http://www.elsevier.com/fundingbodies
Proofs
When your
manuscript is received by the Publisher it is considered to be in its final form. Proofs are not to be regarded as "drafts".
One
set of page proofs in PDF format will be sent by e-mail to the corresponding Author, to be checked for typesetting/editing. No changes
in, or additions to, the accepted (and subsequently edited) manuscript will be allowed at this stage. Proofreading is solely your responsibility.
Elsevier will do everything possible to get your article corrected and published as quickly and accurately as possible. In order
to do this we need your help. When you receive the (PDF) proof of your article for correction, it is important to ensure that all of
your corrections are sent back to us in one communication. Subsequent corrections will not be possible, so please ensure your first sending
is complete. Note that this does not mean you have any less time to make your corrections, just that only one set of corrections will
be accepted.
Author Enquiries
For author enquiries please visithttp://authors.elsevier.com/TrackPaper.html
for the facility to track accepted articles and set up e-mail alerts to inform you when an article's status changes. There is also information
on artwork guidelines, copyright information, and answers to frequently asked questions.
