The Journal of Chromatography B publishes papers on developments in separation science relevant to biology and biomedical research including
both fundamental advances and applications.
Analytical techniques which may be considered include the various facets of chromatography,
electrophoresis and related methods, affinity and immunoaffinity-based methodologies, hyphenated and ... click here for full Aims & Scope
The Journal of Chromatography B publishes papers on developments in separation science relevant to biology and biomedical research including
both fundamental advances and applications.
Analytical techniques which may be considered include the various facets of chromatography,
electrophoresis and related methods, affinity and immunoaffinity-based methodologies, hyphenated and other multi-dimensional techniques,
and microanalytical approaches. The journal also considers articles reporting developments in sample preparation, detection techniques
including mass spectrometry, and data handling and analysis.
Developments related to preparative separations for the isolation
and purification of components of biological systems may be published, including chromatographic and electrophoretic methods, affinity
separations, field flow fractionation and other preparative approaches.
Applications to the analysis of biological systems
and samples will be considered when the analytical science contains a significant element of novelty, e.g. a new approach to the separation
of a compound, novel combination of analytical techniques, or significantly improved analytical performance. Areas to be considered include:
•the qualitative and quantitative analysis of biopolymers including proteins, peptides and their post-translational modifications
as well as nucleic acids and glycans •the comparative analysis of biological systems using proteomics, genomics, metabonomics
and other "omics" approaches
•clinical analysis, pharmacokinetics, metabolism, therapeutic drug monitoring, toxicological analysis,
doping analysis, veterinary applications, analysis of environmental contaminants in biological systems
•the screening and
profiling of body fluids, tissues, cells, biological matrices and systems, analysis of endogenous compounds, biomarkers
•identification
of new bioactive compounds
Applications which utilize published or commercial analytical or preparative protocols with little
or no modification or where the results of the application rather than the analytical methodology comprise the major element of novelty
of the manuscript should be directed to more specialized journals. Modifications to a previously published method may be considered for
a short communication in cases where the improvement in performance is significant. Reports of analytical methods for compounds in early
pharmaceutical development often lack general interest and will not be published unless the authors can demonstrate the broader significance
of the methodology involved. Quality control analyses of bulk drugs, natural products or pharmaceutical formulations are not within scope.
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