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GENE EXPRESSION PATTERNS
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!!! Important information for NIH authors !!!
Peer Review Policy statement
Gene Expression Patterns
publishes high quality descriptive studies of the developmental expression of specific genes, or large gene sets, that have potential or known importance for understanding mechanisms of development.
We offer authors a simple, fast and transparent review process in which reviewers evaluate manuscripts based on publicly available criteria, and only minor revisions are allowed.
We have separate sets of review criteria for in situ studies of spatial and temporal gene expression, and for studies of temporal expression of large gene sets.
If manuscripts require minor improvement to be suitable for publication, reviewers are asked to request a revision and give specific information on the changes required.
Manuscripts that require major improvement to meet the criteria for publication will be rejected, with comments on the deficiencies, but may not receive a detailed review. Examples are a lack of novelty or relevance, poor quality of data, or a major deficiency in detail on the sites or timing of expression.
Resulting from the above, the recommendation the reviewer makes to the Editor will be one of the below:
•ACCEPT (no modification required)
• REVISE (only minor improvements required to meet criteria for publication)
• REJECT (major changes would be required to meet criteria for publication)
The Editor will, based on the reviews and his/her own evaluation, come to a decision which is communicated to the author via the online reviewing system.
Review criteria for studies of spatial and temporal gene expression
• The study must fulfill one of the following:
- An analysis of one or more genes in all embryo tissues
- If a study in a specific developing organ, it reports expression of several genes, or of a single gene only if it has high intrinsic interest
- It reports the results of an in situ screen
• The study must provide novel data on a gene(s) of interest to developmental biologists.
• The study must be detailed and with high quality data, such that it provides a definitive analysis of the sites and timing of gene expression. Studies of a large number of genes do not require the comprehensive analysis that is essential for studies of one or several genes.
• There should be sound evidence for the specificity of detection of gene expression, and precise information provided on the reagents, such as antibody or in situ hybridisation probes.
• For genes already analysed in another species, the study must provide significant new insight, such as differences in expression or more detailed information that may be functionally important.
• Any functional speculations should be brief and informative.
• For studies using gene regulatory elements or gene knock-ins to drive reporter expression, they should present a thorough analysis of gene regulatory regions, or report useful tools, such as lines generated in gene trap screens.
Review criteria for studies of temporal expression of large gene sets
• The study must be high quality, rigorous and relevant to developmental biology.
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