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NITRIC OXIDE: BIOLOGY AND CHEMISTRY
Official Journal of the NITRIC OXIDE Society

Guide for Authors

Nitric Oxide: Biology and Chemistry is an international journal dedicated to the dissemination of fundamental knowledge in all areas of nitric oxide research. The journal features Original Contributions (peer-reviewed, high-quality research investigations representing new and significant contributions to basic and clinical science), Brief Reviews (peer-reviewed articles representing reviews of major areas within the field of nitric oxide research), Brief Communications (peer-reviewed brief studies that are highly significant and timely), Analytical Methods (peer-reviewed articles dealing with new methods of analysis involving nitric oxide), Hypothesis Articles (current state-of-the-art brief reviews of the frontier area of nitric oxide research), Current Trends (articles focusing on current and future directions of nitric oxide research), Letters to the Editor (comments on articles published in the journal and on other matters of interest to the field of nitric oxide research), and Announcements and Calendar (notices of forthcoming conferences, courses, and other events pertaining to nitric oxide research).

There are no page charges.

Submission of Manuscripts

It is a condition of publication that all manuscripts must be written in clear and grammatical English and be submitted to the NITRIC OXIDE Web site at http://ees.elsevier.com/nox. Minimal exceptions will be allowed. If you are unable to provide an electronic version of your paper, please contact the Editorial Office prior to submission (e-mail: nox@elsevier.com; telephone; (619) 699-6337; fax: (619) 699-6700).

Authors who would like information about language editing and copyediting services pre- and post-submission should visit http://www.elsevier.com/wps/find/authorshome.authors/languagepolishing or contact authorsupport@elsevier.com for more information. Please note Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside vendors through our services or in any advertising. For more information please refer to our Terms and Conditions at http://www.elsevier.com/wps/find/termsconditions.cws_home/termsconditions.

Policy regarding publication of experiments on unanesthetized animals conforms with the standards for use of laboratory animals established by the Institute of Laboratory Animal Resources, U.S. National Academy of Sciences. Experiments in which curariform agents are used must be justified and details of the steps taken to reduce or avoid distress to the animal must be provided, particularly with regard to electrical stimulation.

Original papers only will be considered. Manuscripts are accepted for review with the understanding that the same work has not been published, that it is not under consideration for publication elsewhere, and that its submission for publication has been approved by all of the authors and by the institution where the work was carried out. It is the responsibility of the corresponding author to obtain agreement of all the coauthors of the manuscript prior to its submission to the journal. Abstracts of oral or poster presentations are not considered to constitute previous publication. Presentation of material in preliminary communications normally will not preclude publication of a full paper in NITRIC OXIDE, provided that the full paper contains additional information that justifies its publication and does not repeat the presentation of the same data that supported the preliminary communication. The manuscript should be accompanied by PDFs of all preliminary communications and of all relevant manuscripts that are in press or under editorial consideration by another journal. Authors must verify the wording of any cited personal communication with the persons who supplied the information and obtain approval for the use of their names in connection with the quoted information for the citation of unpublished work; written evidence of such approval should accompany the manuscript. All material published in NITRIC OXIDE represents the opinions of the authors and should not be construed to reflect the opinions of the Editors or the Publisher.

Upon acceptance of an article, authors will be asked to transfer copyright (for more information on copyright, see http://authors.elsevier.com). This transfer will ensure the widest possible dissemination of information. A letter will be sent to the corresponding author confirming receipt of the manuscript. A form facilitating transfer of copyright will be provided after acceptance.

If material from other copyrighted works is included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: contact Elsevier Global Rights Department, P.O. Box 800, Oxford OX5 1DX, UK; phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: permissions@elsevier.com.

Reviews
Brief Reviews may be solicited or unsolicited. Unsolicited Brief Reviews should be submitted initially as a 2-page outline for consideration and approval by the Editors. Solicited Brief Reviews should be approximately 10 pages in length (about 25-30 double-spaced manuscript pages). A Brief Review should have an Abstract or Summary of 300-500 words.

Preparation of Manuscript

Manuscripts should be double-spaced throughout. All pages should be numbered consecutively and organized as follows.

The title page (p. 1) should contain the article title, authors' names and complete affiliations, footnotes to the title, and the address and contact numbers (phone, fax, e-mail) of the person to whom correspondence should be sent.

An abstract (p. 2) consisting of a single paragraph of 150-250 words must be included. Keywords should be listed immediately after the abstract.

The introduction should be informative and present the background, rationale, and objective of the study. The introduction is to be prepared without subheadings.

Experimental procedures should be informative and presented in sufficient detail to enable others to conduct similar novel experiments without the necessity to refer to other references or sources.

Results and Discussion should be two separate and distinct sections, each with subheadings where appropriate. The Results section should present and explain the data in a clear manner. A detailed explanation of any illustrative data (figures, tables) should be given in the text. No discussion of the data, however, should be presented in the Results. The Discussion section should be informative and include all explanations and discussions of data. Be certain that the conclusions and any hypotheses made are derived from, and are consistent with, the data presented.

Acknowledgments should be brief and precede the Reference section.

References must include all authors' names and the title of the article. They should be cited in the text by an Arabic numeral in square brackets and listed at the end of the paper in numerical order typed double-spaced on a separate sheet. Abbreviations of journal titles should conform to those of the most recent edition of Chemical Abstracts Service Source Index. Please note the following examples.

[1] M.G. Ferrini, D. Vernet, T.R. Magee, A. Shahed, A. Qian, J. Rajfer, N.F. Gonzalez-Cadavid, Antifibrotic role of inducible nitric oxide synthase, Nitric Oxide 6 (2002) 247-352.

[2] R. Hesketh, The Oncogene FactsBook, Academic Press, San Diego, 1995.

[3] J.S. Beckman, The physiological and pathological chemistry of nitric oxide, in: J. Lancaster (Ed.), Nitric Oxide: Principles and Actions, Academic Press, San Diego, pp. 1-82.

Footnotes to the text should be identified by superscript Arabic numerals and should be typed double-spaced on a separate page: footnotes to tables should be identified by superscript lowercase italic letters (a,b, soft-etc.) and placed at the bottom of the table.

Tables should be numbered with Arabic numerals and cited consecutively in the text. Each table should be titled and typed double-spaced on a separate sheet. Units must be clearly indicated for each of the entries in the table.

Figures should be cited consecutively in the text by Arabic numerals. Legends should be typed double-spaced on a separate page. Please visit our Web site at http://authors.elsevier.com/artwork for detailed instructions on preparing electronic artwork.

One page of color figures will be published free of charge in each article. Additional figures in color will be published if the authors defray costs. However, if together with your accepted article, you submit usable color figures, then Elsevier will ensure, at no additional charge, that these figures will appear in color on the Web (e.g., ScienceDirect and other sites) regardless of whether these illustrations are reproduced in color in the printed version. For color reproduction in print, you will receive information regarding the costs from Elsevier after receipt of your accepted article. [Please note: Because of technical complications that can arise in converting color figures to "gray scale" (for the printed version should you not opt for color in print), please submit in addition usable black-and-white files corresponding to all the color illustrations.]

Suggestions for cover art are welcome. A short (one-line) legend should also accompany each photograph.

Nomenclature. All nomenclature should be simple, unambiguous, and in conformity with the conventions developed by the IUPAC. Because compound names ending in -ic and -ous are not recommended (the oxidation state is not well defined), systematic nomenclature is preferred.

Proofs

PDF proofs will be e-mailed to the corresponding author. Corrections should be returned promptly to avoid a delay in publication.


E-Offprints

The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail or, alternatively, 25 free paper offprints. The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use.
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