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Molecular Genetics and Metabolism is a contribution to the understanding of the metabolic basis of disease. The journal publishes
articles describing investigations that use the tools of biochemistry and molecular biology for studies of normal and diseased states.
In addition to original research articles, occasional ... click here for full Aims & Scope
Molecular Genetics and Metabolism is a contribution to the understanding of the metabolic basis of disease. The journal publishes
articles describing investigations that use the tools of biochemistry and molecular biology for studies of normal and diseased states.
In addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters
to the editor are considered.
Research Areas include:
• Inherited Metabolic Diseases
- Biochemical studies
of primary enzyme defects
- Molecular genetic analyses of mutations
- Pathogenesis of these disorders, including not only primary
but also secondary metabolic alterations
• Systems Biology
- Functional integration of biochemical network modules
- Moonlighting functions of proteins
• Intercellular and Intracellular Metabolic Relationships
- Biochemical
interactions between cells
- Functional roles of and interactions between subcellular compartments and distinct regions within these
cellular spaces, termed microcompartments
- Metabolic relations between individual enzymes and pathways
• Cellular
Catalysts
- Protein and nonprotein catalyst in normal and deranged cellular metabolism
- Relationships between the structure
and function of catalytic molecules
- Interaction of these catalysts with other cellular components
• Disease Pathogenesis
- Underlying mechanisms of inherited and acquired diseases
- Relationships between genotype and phenotype at the biochemical
and molecular levels
• Treatment
- Drug, protein and dietary interventions
- Transplantation and gene therapy
- Multicenter clinical trials
Advances in nanomedicine, nanopediatrics and nanotechnology are also welcome.
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Editor-in-Chief:
E.R.B. McCabe