Guide for Authors
Is the official journal of the
Society for Inherited Metabolic Disorders
!!! Important information for NIH authors !!!
Sponsored Articles
Molecular Genetics and Metabolism offers authors the option to sponsor non-subscriber access to
their articles on Elsevier's electronic publishing platforms. For more information please view our
Sponsored Articles page.
Molecular Genetics and Metabolism is a contribution to the understanding of the metabolic basis of disease.
The journal publishes articles describing investigations that use the tools of biochemistry and molecular biology for studies of normal
and diseased states.
Research Areas include:
•Inherited Metabolic Diseases
- Biochemical studies of primary enzyme
defects
- Molecular genetic analyses of mutations
- Pathogenesis of these disorders, including not only primary but also secondary
metabolic alterations
• Systems Biology
- Functional integration of biochemical network modules
- Moonlighting functions
of proteins
• Intercellular and Intracellular Metabolic Relationships
- Biochemical interactions between cells
- Functional
roles of and interactions between subcellular compartments and distinct regions within these cellular spaces, termed microcompartments
- Metabolic relations between individual enzymes and pathways
• Cellular Catalysts
- Protein and nonprotein catalyst in
normal and deranged cellular metabolism
- Relationships between the structure and function of catalytic molecules
- Interaction
of these catalysts with other cellular components
• Disease Pathogenesis
- Underlying mechanisms of inherited and acquired
diseases
- Relationships between genotype and phenotype at the biochemical and molecular levels
• Treatment
- Drug,
protein and dietary interventions
- Transplantation and gene therapy
- Multicenter clinical trials
- Pharmacogenetics /
Pharmacogenomics
Submitted manuscripts claiming to be a demonstration of a new mutation will be rejected and returned to authors
without review unless the authors present results of a search for the new mutation in at least 100 chromosomes from unaffected individuals
of the same ethnic background as the patient(s) with the new mutation.
Authors should perform a power calculation to determine how
many subjects they need to study in order to find a significant association between a sequence variation and a disorder. The results
of the power calculation should be included in the methods section of the manuscript. Submitted manuscripts without a power calculation
will be rejected and returned to authors without review.
Authors attempting to demonstrate genotype/phenotype correlation should
review the literature below to help them interpret their results:
R. Dorfman, A. Sandford et al., Complex two-gene modulation of
lung disease severity in children with cystic fibrosis, J. Clin. Invest. 118 (2008) 1040-1049,
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2248329.
K.M. Dipple, E.R.B. McCabe, Modifier genes convert "simple" Mendelian disorders to complex traits, Mol. Genet. Metab. 71 (2000) 43-50.
K.M. Dipple, E.R.B. McCabe, Phenotypes of patients with "simple" Mendelian disorders are complex traits: Threshholds, modifiers, and
systems dynamics. Am. J. Hum. Genet. 66 (2000) 1729-1735.
K.M. Dipple, J.K. Phelan, E.R.B. McCabe, Consequences of complexity within
biological networks: Robustness and health, or vulnerability and disease. Mol. Genet. Metab. 74 (2001) 45-50.
C.R. Scriver, P.J.
Waters, Monogenic traits are not simple: Lessons learned from phenylketonuria. Trends Genet. 15 (1999) 267-272.
J. Vockley, P. Rinaldo,
M.J. Bennett, G.D. Vladutiu, Synergistic heterozygosity: Disease resulting from multiple partial defects in one or more metabolic pathways.
Mol. Genet. Metab. 71 (2000) 10-18.
Types of paper
In addition to original
research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are considered.
Original articles will be considered on the basis of the originality and quality of the work, the clarity of the presentation,
and the relevance of the research to the goal of the journal. At the discretion of the Editor, an original article may be accompanied
by a Commentary by a member of the Editorial Board or another contributor.
Minireviews will describe timely advances within
the scope of the journal, emphasizing emerging topical areas and/or critically analyzing existing data. Contributors should communicate
with the Editor before preparing or submitting a review in order to determine if the topic and intent are considered appropriate. At
the discretion of the Editor, reviews may be accompanied by comment from one of the Editors or another contributor. Minireviews may be
any length and may include any number of references. Figures and tables may be included.
Brief Communications will be considered
for publication with an expedited review. These short manuscripts should be no more than 5 manuscript pages (approximately 1000 words)
in length with a limit of one figure or table. Standard section headings should be utilized and the abstract should be limited to a few
sentences (75 words or less).
Letters to the Editor will be considered for rapid publication if they lie within the purview
of the journal and if they contain new information, comment on published work, or new theoretical suggestions. These should be brief
(300 words or less) and without subject headings. One table or figure will be allowed.
Contact details for submission
Please submit your articles via the journal's online submission and editorial system:
http://ees.elsevier.com/mgm/
Customer support is available 24/7:
Please use our help site at:
http://epsupport.elsevier.com/. Here
you will be able to learn more about online submission system via interactive tutorials, explore a range of common problem solutions
via our knowledgebase, and find answers to frequently asked questions. You will also find our 24/7 support contact details should you
need any assistance from one of our customer service representatives.
Questions on submission and reviewing process:
Please contact the Editorial Office at
MolGenetMetab@mednet.ucla.edu.
Ethics in Publishing
For information on Ethics in Publishing and Ethical
guidelines for journal publication see
http://www.elsevier.com/publishingethics and
http://www.elsevier.com/ethicalguidelines.
Conflict of interest
All authors are requested to disclose any actual or potential conflict of interest
including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted
work that could inappropriately influence, or be perceived to influence, their work. See also
http://www.elsevier.com/conflictsofinterest.
Submission declaration
Submission of an article implies that the work described has not been published previously
(except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication
elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was
carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without
the written consent of the copyright-holder.
Copyright
Upon acceptance
of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more information on this and copyright see
http://www.elsevier.com/copyright).
Acceptance of the agreement will ensure the widest possible dissemination of information. An e-mail will be sent to the corresponding
author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this
agreement.
Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation
within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other
derivative works, including compilations and translations (please consult
http://www.elsevier.com/permissions). If excerpts
from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s)
in the article. Elsevier has preprinted forms for use by authors in these cases: please consult
http://www.elsevier.com/permissions.
Retained author rights
As an author you (or your employer or institution) retain certain rights; for details
you are referred to:
http://www.elsevier.com/authorsrights.
Role of the
funding source
You are requested to identify who provided financial support for the conduct of the research and/or preparation
of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation
of data; in the writing of the report; and in the decision to submit the paper for publication. If the funding source(s) had no such
involvement then this should be stated. Please see
http://www.elsevier.com/funding.
Funding body agreements and policies
Elsevier has established agreements and developed policies to allow authors whose
articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions
of their grant awards. To learn more about existing agreements and policies please visit
http://www.elsevier.com/fundingbodies.
Language and language services
Please write your text in good English (American or British usage is accepted,
but not a mixture of these). Authors who require information about language editing and copyediting services pre- and post-submission
please visit
http://www.elsevier.com/languagepolishing or our customer support site at
http://epsupport.elsevier.com
for more information. Please note Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside
vendors through our services or in any advertising. For more information please refer to our Terms & Conditions:
http://www.elsevier.com/termsandconditions.
Submission
Submission to this journal proceeds totally online and you will be guided stepwise through
the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is
used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the
review process, these source files are needed for further processing after acceptance. All correspondence, including notification of
the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.
Referees
Please submit, with the manuscript, the names, addresses and e-mail addresses of 3 potential referees.
Note that the editor retains the sole right to decide whether or not the suggested reviewers are used.
Use of wordprocessing software
It
is important that the file be saved in the native format of the wordprocessor used. The text should be in single-column format. Keep
the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular,
do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts
etc. Do not embed "graphically designed" equations or tables, but prepare these using the wordprocessor's facility. When preparing tables,
if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs,
not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also
the Guide to Publishing with Elsevier:
http://www.elsevier.com/guidepublication). Do not import the figures into the text
file but, instead, indicate their approximate locations directly in the electronic text and on the manuscript. See also the section on
Electronic illustrations.
To avoid unnecessary errors you are strongly advised to use the "spell-check" and "grammar-check" functions
of your wordprocessor.
Article structure
Subdivision - numbered sections
Divide your article into clearly defined and numbered sections. Subsections should
be numbered 1.1 (then 1.1.1, 1.1.2, ...), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for
internal cross-referencing: do not just refer to "the text". Any subsection may be given a brief heading. Each heading should appear
on its own separate line.
Introduction
State the objectives of the
work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.
Material and methods
Provide sufficient detail to allow the work to be reproduced. Methods already
published should be indicated by a reference: only relevant modifications should be described.
Theory/calculation
A Theory section should extend, not repeat, the background to the article already dealt with in
the Introduction and lay the foundation for further work. In contrast, a Calculation section represents a practical development from
a theoretical basis.
Results
Results should be clear and concise.
Discussion
This should explore the significance of the results of the work, not repeat them. A combined
Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.
Conclusions
The main conclusions of the study may be presented in a short Conclusions section, which
may stand alone or form a subsection of a Discussion or Results and Discussion section.
Appendices
If there is more than one appendix, they should be identified as A, B, etc. Formulae and equations in
appendices should be given separate numbering: Eq. (A.1), Eq. (A.2), etc.; in a subsequent appendix, Eq. (B.1) and so on.
Essential title page information
•
Title.
Concise and informative. Titles are often
used in information-retrieval systems. Avoid abbreviations and formulae where possible.
•
Author names and affiliations.
Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses
(where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the
author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name,
and, if available, the e-mail address of each author.
•
Corresponding author.
Clearly indicate who will handle
correspondence at all stages of refereeing and publication, also post-publication.
Ensure that telephone and fax numbers (with country
and area code) are provided in addition to the e-mail address and the complete postal address.
•
Present/permanent
address.
If an author has moved since the work described in the article was done, or was visiting at the time, a "Present address"
(or "Permanent address") may be indicated as a footnote to that author's name. The address at which the author actually did the work
must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.
Abstract
A concise and factual abstract is required. The abstract should state briefly the purpose of the
research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able
to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard
or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself.
Keywords
Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding
general and plural terms and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations: only abbreviations firmly
established in the field may be eligible. These keywords will be used for indexing purposes.
Abbreviations
Define abbreviations that are not standard in this field in a footnote to be placed on the first page of
the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the
footnote. Ensure consistency of abbreviations throughout the article.
Acknowledgements
Collate acknowledgements in a separate section at the end of the article before the references and do not, therefore, include
them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g.,
providing language help, writing assistance or proof reading the article, etc.).
Nomenclature
and units
Whenever
enzymes are the subject of reporting, the Enzyme Commission (EC) number should be used for accurate
identification and retrieval purposes. The Internet address for the Enzyme Commission is
http://www.bis.med.jhmi.edu/bio/search/FILT/enzyme.html.
Genbank
DNA sequences and GenBank accession numbers. Whenever nucleic acid and/or protein sequence
information is presented, an accession number from EMBL/GenBank or NBRF should be submitted. Authors wishing to enable other scientists
to use the accession numbers cited in their papers via links to these sources, should type this information in the following manner:
For each and every accession number cited in an article, authors should type the accession number in bold, underlined text. Letters in
the accession number should always be capitalized (see example below). This combination of letters and format will enable the typesetter
to recognize the relevant texts as accession numbers and add the required link to the GenBank sequences.
Example: GenBank accession
nos.
AI631510 , AI631511 , AI632198 , and
BF223228 ), a B-cell tumor from a chronic lymphatic leukemia (GenBank accession
no.
BE675048 ), and a T-cell lymphoma (GenBank accession
no. AA361117 ).
Authors are encouraged to check accession
numbers used very carefully. An error in a letter or number can result in a dead link. In the final version of the
printed article,
the accession number text will not appear bold or underlined. In the final version of the
electronic copy, the accession number
text will be linked to the appropriate source in the NCBI databases, enabling readers to go directly to that source from the article.
Human gene mutations should be named in accord with the recommendations of the Nomenclature Working Group (Antonarakis et al.,
Hum. Mutat. 11 (1998) 1-3; den Dunnen and Antonarakis, Hum. Mutat. 15 (2000) 7-12).
Math formulae
Present simple formulae in the line of normal text where possible and use the solidus (/) instead of a horizontal
line for small fractional terms, e.g., X/Y. In principle, variables are to be presented in italics. Powers of e are often more conveniently
denoted by exp. Number consecutively any equations that have to be displayed separately from the text (if referred to explicitly in the
text).
Footnotes
Footnotes should be used sparingly. Number them consecutively
throughout the article, using superscript Arabic numbers. Many wordprocessors build footnotes into the text, and this feature may be
used. Should this not be the case, indicate the position of footnotes in the text and present the footnotes themselves separately at
the end of the article. Do not include footnotes in the Reference list.
Table footnotes
Indicate each footnote in a
table with a superscript lowercase letter.
Artwork
Electronic artwork
General points
• Make sure you use uniform lettering and sizing
of your original artwork.
• Save text in illustrations as "graphics" or enclose the font.
• Only use the following
fonts in your illustrations: Arial, Courier, Times, Symbol.
• Number the illustrations according to their sequence in the text.
• Use a logical naming convention for your artwork files.
• Provide captions to illustrations separately.
•
Produce images near to the desired size of the printed version.
• Submit each figure as a separate file.
A detailed guide
on electronic artwork is available on our website:
http://www.elsevier.com/artworkinstructions
You are urged
to visit this site; some excerpts from the detailed information are given here.
Formats
Regardless of the application
used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats (note the resolution
requirements for line drawings, halftones, and line/halftone combinations given below):
EPS: Vector drawings. Embed the font or save
the text as "graphics".
TIFF: color or grayscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line
drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications please supply "as is".
Please
do not:
• Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document;
• Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low;
• Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.
Color
artwork
Please make sure that artwork files are in an acceptable format (TIFF, EPS or MS Office files) and with the correct
resolution. If, together with your accepted article, you submit usable color figures then Elsevier will ensure, at no additional charge,
that these figures will appear in color on the Web (e.g., ScienceDirect and other sites) regardless of whether or not these illustrations
are reproduced in color in the printed version.
For color reproduction in print, you will receive information regarding the costs
from Elsevier after receipt of your accepted article. Please indicate your preference for color in print or on the Web only. For
further information on the preparation of electronic artwork, please see
http://www.elsevier.com/artworkinstructions.
Please
note: Because of technical complications which can arise by converting color figures to "gray scale" (for the printed version should
you not opt for color in print) please submit in addition usable black and white versions of all the color illustrations.
Figure captions
Ensure that each illustration has a caption. Supply captions separately, not attached
to the figure. A caption should comprise a brief title (
not on the figure itself) and a description of the illustration. Keep
text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.
Tables
Number tables consecutively in accordance with their appearance in the text. Place footnotes to tables below the
table body and indicate them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that
the data presented in tables do not duplicate results described elsewhere in the article.
References
Citation in text
Please ensure that every reference
cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be given in full.
Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the text. If these
references are included in the reference list they should follow the standard reference style of the journal and should include a substitution
of the publication date with either "Unpublished results" or "Personal communication" Citation of a reference as "in press" implies that
the item has been accepted for publication.
Web references
As a minimum,
the full URL should be given. Any further information, if known (DOI, author names, dates, reference to a source publication, etc.),
should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired,
or can be included in the reference list.
References in a special issue
Please ensure that the words 'this issue' are added to any references in the list (and any citations in the text) to other articles
in the same Special Issue.
Reference style
Text: Indicate
references by number(s) in square brackets in line with the text. The actual authors can be referred to, but the reference number(s)
must always be given.
Example: "..... as demonstrated [3,6]. Barnaby and Jones [8] obtained a different result ...."
List:
Number the references (numbers in square brackets) in the list in the order in which they appear in the text.
Examples:
Reference to a journal publication:
[1] J. van der Geer, J.A.J. Hanraads, R.A. Lupton, The art of writing a scientific article,
J. Sci. Commun. 163 (2000) 51-59.
Reference to a book:
[2] W. Strunk Jr., E.B. White, The Elements of Style, third ed., Macmillan,
New York, 1979.
Reference to a chapter in an edited book:
[3] G.R. Mettam, L.B. Adams, How to prepare an electronic version of
your article, in: B.S. Jones, R.Z. Smith (Eds.), Introduction to the Electronic Age, E-Publishing Inc., New York, 1999, pp. 281-304.
Journal abbreviations source
Journal names should be abbreviated according to
Index Medicus journal
abbreviations:
http://www.nlm.nih.gov/tsd/serials/lji.html;
List of serial title word abbreviations:
http://www.issn.org/2-22661-LTWA-online.php;
CAS (Chemical Abstracts Service):
http://www.cas.org/sent.html.
Supplementary
material
Elsevier accepts electronic supplementary material to support and enhance your scientific research. Supplementary
files offer the author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images,
background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of
your article in Elsevier Web products, including ScienceDirect:
http://www.sciencedirect.com. In order to ensure that your
submitted material is directly usable, please ensure that data are provided in one of our recommended file formats. Authors should submit
the material in electronic format together with the article and supply a concise and descriptive caption for each file. Video files:
please supply 'stills' with your files: you can choose any frame from the video or make a separate image. These will be used instead
of standard icons and will personalize the link to your supplementary information. For more detailed instructions please visit our artwork
instruction pages at
http://www.elsevier.com/artworkinstructions.
Submission
checklist
It is hoped that this list will be useful during the final checking of an article prior to sending it to the journal's
Editor for review. Please consult this Guide for Authors for further details of any item.
Ensure that the following items are
present:
One Author designated as corresponding Author:
• E-mail address
• Full postal address
• Telephone
and fax numbers
All necessary files have been uploaded
• Keywords
• All figure captions
• All tables (including
title, description, footnotes)
Further considerations
• Manuscript has been "spellchecked" and "grammar-checked"
•
References are in the correct format for this journal
• All references mentioned in the Reference list are cited in the text,
and vice versa
• Permission has been obtained for use of copyrighted material from other sources (including the Web)
•
Color figures are clearly marked as being intended for color reproduction on the Web (free of charge) and in print or to be reproduced
in color on the Web (free of charge) and in black-and-white in print
• If only color on the Web is required, black and white
versions of the figures are also supplied for printing purposes
For any further information please visit our customer support site
at
http://epsupport.elsevier.com.
Additional information
Authors
can suggest figures to the Editor for use as the
cover figure for an issue. Cover figures should be in color and include data
or a schematic model. There will be no charge to the authors for printing the color figure on the journal cover.
Use of the Digital Object Identifier
The
Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character
string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore,
it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic
information. The correct format for citing a DOI is shown as follows (example taken from a document in the journal
Physics Letters
B):
doi:10.1016/j.physletb.2003.10.071
When you use the DOI to create URL hyperlinks to documents on the web, they are guaranteed
never to change.
Proofs
One set of page proofs (as PDF files) will be
sent by e-mail to the corresponding author (if we do not have an e-mail address then paper proofs will be sent by post) or, a link will
be provided in the e-mail so that authors can download the files themselves. Elsevier now provides authors with PDF proofs which can
be annotated; for this you will need to download Adobe Reader version 7 (or higher) available free from
http://www.adobe.com/products/acrobat/readstep2.html.
Instructions on how to annotate PDF files will accompany the proofs (also given online). The exact system requirements are given at the
Adobe site:
http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win.
If you do not wish to use the PDF annotations
function, you may list the corrections (including replies to the Query Form) and return them to Elsevier in an e-mail. Please list your
corrections quoting line number. If, for any reason, this is not possible, then mark the corrections and any other comments (including
replies to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail, or by post. Please use this proof
only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the
article as accepted for publication will only be considered at this stage with permission from the Editor. We will do everything possible
to get your article published quickly and accurately. Therefore, it is important to ensure that all of your corrections are sent back
to us in one communication: please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed.
Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of your article if no response is received.
Offprints
The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail.
The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer
outlining the terms and conditions of use. Additional paper offprints can be ordered by the authors. An order form with prices will be
sent to the corresponding author.
Additional information
US National
Institutes of Health (NIH) voluntary posting ("Public Access") policy.
Elsevier facilitates author response to the
NIH voluntary posting request (referred to as the NIH "Public Access Policy"; see
http://www.nih.gov/about/publicaccess/index.htm)
by posting the peer-reviewed author's manuscript directly to PubMed Central on request from the author, 12 months after formal publication.
Upon notification from Elsevier of acceptance, we will ask you to confirm via e-mail (by e-mailing us at
NIHauthorrequest@elsevier.com)
that your work has received NIH funding and that you intend to respond to the NIH policy request, along with your NIH award number to
facilitate processing. Upon such confirmation, Elsevier will submit to PubMed Central on your behalf a version of your manuscript that
will include peer-review comments, for posting 12 months after formal publication. This will ensure that you will have responded fully
to the NIH request policy. There will be no need for you to post your manuscript directly with PubMed Central, and any such posting is
prohibited.
For inquiries relating to the submission
of articles (including electronic submission where available) please visit this journal's homepage. You can track accepted articles at
http://www.elsevier.com/trackarticle and set up e-mail alerts to inform you of when an article's status has changed. Also
accessible from here is information on copyright, frequently asked questions and more. Contact details for questions arising after acceptance
of an article, especially those relating to proofs, will be provided by the publisher.
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