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Genomics

Genomics
ISSN: 0888-7543
Imprint: ACADEMIC PRESS

Statistics
Impact Factor: 3.075
Issues per year: 12

Guide for Authors





Introduction - Full length articles - Contact details for submission - Page charges
BEFORE YOU BEGIN
Ethics in Publishing - Animal Experimentation - Conflict of interest - Submission declaration - Copyright - Retained author rights - Role of the funding source - Funding body agreements and policies - Sponsored articles - Language and language services - Submission - Referees - Additional Information
PREPARATION
Use of wordprocessing software - Article structure - Subdivision - numbered sections - Introduction - Material and methods - Theory/calculation - Results - Discussion - Conclusions - Appendices - Vitae - Essential title page information - Abstract - Keywords - Abbreviations - Acknowledgements - Nomenclature and Units - GenBank - Math formulae - Footnotes - Electronic artwork - Color artwork - Figure captions - Tables - References - Citation in text - Web references - References in a special issue - Reference style - Journal abbreviations source - Supplementary material - Submission checklist - Additional Information
AFTER ACCEPTANCE
Use of the Digital Object Identifier - Proofs - Offprints - Additional Information
AUTHOR INQUIRIES


Introduction

The goal of Genomics is to promote the understanding of the structure, function, and evolution of genomes in all kingdoms of life and the application of genome sciences and technologies to challenging problems in biology and medicine. The scope of the journal is broad and we welcome original, full-length, and timely papers in all of the following areas:

• Comparative genomics analysis that yields valuable insights into conserved and divergent aspects of function, regulation, and evolution

• Bioinformatics and computational biology with particular emphasis on data mining and improvements in data annotation and integration

• Functional genomics approaches involving the use of large-scale and/or high-throughput methods to understand genome-scale function and regulation of transcriptomes and proteomes

• Identification of genes involved in disease and complex traits, including responses to drugs and other xenobiotics

• Significant advances in genetic and genomics technologies and their applications, including chemical genomics

In addition to full-length papers, Genomics accepts a number of different article types.

As a result of Genomics' strict quality measures, the journal rejects as much of 70 % of all submissions received.

Each manuscript should be accompanied by a Cover letter outlining the basic findings of the manuscript and their significance. Please submit, with the manuscript, the names and addresses of five potential referees.

Full length articles

Organization should be Abstract, Introduction, Results, Discussion, Materials and methods, Acknowledgments, and References. There is a limit of 8 display items (figures plus tables) and 50 references. Manuscripts should be no more than 8 published pages. Accepted papers that are over 8 pages may be returned to the authors for additional editing. Manuscript length can be estimated by the total number of characters (spaces included), not the number of typed pages. The average number of characters per published page is approximately 7000. Count each table or figure as 2450 characters and add to the character count of your manuscript text. In other words, a regular submission should have no more than 56,000 characters (that is, 8 published pages).
Readers are invited to submit ideas and proposals for reviews and minireviews; they should not submit complete or finished manuscripts prior to consultation with the editor-in-chief or one of the associate editors.

Minireviews
The journal encourages the submission of concise, highly focused review articles summarizing recent progress in very active areas of research involving the analysis of genomes. Authors wishing to prepare such reviews should submit a short proposal, including an expected date of submission, to the editor.

Special features. In addition to minireviews, special reviews of research programs for mapping and sequencing, historical sketches, genomics news, etc., are published periodically.

Short communications are not encouraged.

Single-gene reports will not be considered unless they are accompanied by significant or novel insights into their structure, evolution, and/or expression. With respect to single genes, functional assertions should be supported by experimental evidence; e.g., functional inferences based solely on routine analysis of homology are insufficient. Authors are encouraged to identify and report any discrepancies between their findings and annotations in the major genome databases.

Manuscripts that do not meet the general criteria or standards for publication in Genomics will be immediately returned to the authors, without detailed review.

Contact details for submission

Articles for Genomics should be submitted via the journal's online submission and editorial system at External link http://ees.elsevier.com/geno.

Customer support is available 24/7:
Please use our help site at: External link http://epsupport.elsevier.com/. Here you will be able to learn more about the online submission and editorial system via interactive tutorials, explore a range of problem solutions via our knowledgebase, and find answers to frequently asked questions. You will also find our 24/7 support contact details should you need any assistance from one of our customer service representatives.

For questions on the submission and reviewing process, please contact the Editorial Office at genomics@elsevier.com.

Page charges

This journal has no page charges.

BEFORE YOU BEGIN

Ethics in Publishing

For information on Ethics in Publishing and Ethical guidelines for journal publication see External link http://www.elsevier.com/publishingethics and External link http://www.elsevier.com/ethicalguidelines.

Animal Experimentation

Circumstances relating to animal experimentation must meet the International Guiding Principles for Biomedical Research Involving Animals as issued by the Council for the International Organizations of Medical Sciences. They are obtainable from: Executive Secretary C.I.O.M.S., c/o WHO, Via Appia, CH-1211 Geneva 27, Switzerland, or at the following URL: External link http://www.cioms.ch/frame_1985_texts_of_guidelines.htm

Authors may also wish to refer to the ethical guidelines published on the website of the International Society for Applied Ethology External link http://www.applied-ethology.org/ethicalguidelines.htm, or read the following article: Sherwin, C.M., Christiansen, S.B., Duncan, I.J., Erhard, H., Lay, D., Mench, J., O'Connor, C., and Petherick, C. (2003), 'Guidelines for the ethical use of animals in applied animal behaviour research', Applied Animal Behaviour Science, 81: 291-305.
Unnecessary cruelty in animal experimentation is not acceptable.

Conflict of interest

All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See also External link http://www.elsevier.com/conflictsofinterest.

Submission declaration

Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without the written consent of the copyright-holder.

Copyright

Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more information on this and copyright see External link http://www.elsevier.com/copyright). Acceptance of the agreement will ensure the widest possible dissemination of information. An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations (please consult External link http://www.elsevier.com/permissions). If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: please consult External link http://www.elsevier.com/permissions.

Retained author rights

As an author you (or your employer or institution) retain certain rights; for details you are referred to: External link http://www.elsevier.com/authorsrights.

Role of the funding source

You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication. If the funding source(s) had no such involvement then this should be stated. Please see External link http://www.elsevier.com/funding.

Funding body agreements and policies

Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies please visit External link http://www.elsevier.com/fundingbodies.

Sponsored articles

This journal offers authors the option to sponsor non-subscriber access to their articles on Elsevier's electronic publishing platforms. For more information please view our Sponsored Articles page at External link http://www.elsevier.com/sponsoredarticles.

Language and language services

Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who require information about language editing and copyediting services pre- and post-submission please visit External link http://www.elsevier.com/languagepolishing or our customer support site at External link http://epsupport.elsevier.com for more information. Please note Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside vendors through our services or in any advertising. For more information please refer to our Terms & Conditions: External link http://www.elsevier.com/termsandconditions.

Submission

Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.

Referees

Please submit, with the manuscript, the names, addresses and e-mail addresses of 3 potential referees. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used.

Additional Information

Sharing information and materials

It is expected that all new biological or other reagents described in papers published in Genomics will be made available freely to all qualified members of the scientific community upon written request. If delays in strain or vector distribution are anticipated, or if these are available from sources other than the author(s), this must be indicated and, if the editor thinks it necessary, explained.

Submission of data to databases

The editorial policy of Genomics is to require the use of databases. Deposit of data in the appropriate database(s) is a condition of publication. New nucleotide data must be submitted and deposited in the DDBJ/EMBL/GenBank databases and an accession number obtained before the paper can be accepted for publication. Submission to any one of the three collaborating databanks is sufficient to ensure data entry in all.

The accession number should be included in the manuscript as a footnote on the title page: "Sequence data from this article have been deposited with the DDBJ/EMBL/GenBank Data Libraries under Accession No. ...." If requested, the database will withhold release of data until publication. The most convenient method for submitting sequence data is by the World Wide Web:

DDBJ via SAKURA, External link http://sakura.ddbj.nig.ac.jp/
EMBL via WEBIN, External link http://www.ebi.ac.uk/embl/Submission/webin.html
GenBank via BankIt, External link http://www.ncbi.nlm.nih.gov/BankIt/
Stand-alone submission tool Sequin, External link http://www.ncbi.nlm.nih.gov/Sequin/
Mouse Genome Informatics, External link http://www.informatics.jax.org/mgihome/

For special types of submissions (for example, genomes, bulk submissions), additional submission protocols are available from the above sites. Database contact information:

DDBJ:
Center for Information Biology and DNA Data Bank of Japan
National Institute of Genetics
1111 Yata
Mishima, Shizuoka 411-8540, Japan
Telephone: 81 55981 6853; Fax: 81 55981 6849
E-mail: ddbj@ddbj.nig.ac.jp
Web URL: External link http://www.ddbj.nig.ac.jp/

EMBL
EMBL Nucleotide Sequence Submissions
European Bioinformatics Institute
Wellcome Trust Genome Campus
Hinxton, Cambridge CB10 1SD, UK
Telephone: 44 1223 494499; Fax: 44 1223 494472
E-mail: datasubs@ebi.ac.uk
Web URL: External link http://www.ebi.ac.uk

GenBank
National Center for Biotechnology Information
National Library of Medicine
Building 38A, Room 8N-802
Bethesda, MD 20894, USA
Telephone: (301) 496-2475; Fax: (301) 480-9241
E-mail: info@ncbi.nlm.nih.gov Web URL: External link http://www.ncbi.nlm.nih.gov

PREPARATION

Use of wordprocessing software

It is important that the file be saved in the native format of the wordprocessor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. Do not embed "graphically designed" equations or tables, but prepare these using the wordprocessor's facility. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: External link http://www.elsevier.com/guidepublication). Do not import the figures into the text file but, instead, indicate their approximate locations directly in the electronic text and on the manuscript. See also the section on Electronic illustrations.
To avoid unnecessary errors you are strongly advised to use the "spell-check" and "grammar-check" functions of your wordprocessor.

Article structure

Subdivision - numbered sections

Divide your article into clearly defined and numbered sections. Subsections should be numbered 1.1 (then 1.1.1, 1.1.2, ...), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for internal cross-referencing: do not just refer to "the text". Any subsection may be given a brief heading. Each heading should appear on its own separate line.

Introduction

State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.

Material and methods

Provide sufficient detail to allow the work to be reproduced. Methods already published should be indicated by a reference: only relevant modifications should be described.

Theory/calculation

A Theory section should extend, not repeat, the background to the article already dealt with in the Introduction and lay the foundation for further work. In contrast, a Calculation section represents a practical development from a theoretical basis.

Results

Results should be clear and concise.

Discussion

This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.

Conclusions

The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section.

Appendices

If there is more than one appendix, they should be identified as A, B, etc. Formulae and equations in appendices should be given separate numbering: Eq. (A.1), Eq. (A.2), etc.; in a subsequent appendix, Eq. (B.1) and so on.

Vitae

Include in the manuscript a short (maximum 100 words) biography of each author, along with a passport-type photograph accompanying the other figures.

Essential title page information

  • Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.
  • Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name, and, if available, the e-mail address of each author.
  • Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that telephone and fax numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address.
  • Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a "Present address" (or "Permanent address") may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.


Abstract

A concise and factual abstract is required. The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself.

Keywords

Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes.

Abbreviations

Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout the article.

Acknowledgements

Collate acknowledgements in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g., providing language help, writing assistance or proof reading the article, etc.).

Nomenclature and Units

Authors must use approved nomenclature for all genes, and all manuscripts will undergo a nomenclature check prior to publication. All unapproved symbols must be replaced with approved symbols (throughout the text and figures). To avoid delays to your manuscript please obtain approval for any new gene symbols prior to submitting your manuscript. Copies of emails documenting the approval of any new symbols should accompany all submissions. Approved human gene symbols may be obtained before submission from the HUGO Gene Nomenclature Committee (HGNC: contact Dr Elspeth Bruford, EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK); e-mail: hgnc@genenames.org; External link http://www.genenames.org/. Approved mouse nomenclature may be obtained before submission from L. J. Maltais, The Jackson Laboratory, Bar Harbor, ME 04609-0800, USA; telephone: (207) 288-6429; fax: (207) 288-6132; e-mail: ljm@informatics.jax.org; External link http://www.informatics.jax.org/nomen/. In mouse, mutant strains and transgenic alleles also require approved symbols; see External link http://www.informatics.jax.org/. Use of unapproved gene symbols will likely delay publication.

Human and mouse protein symbols should be denoted in all capital letters (for example, FGF8). Use of "h" and "m" prefixes to distinguish between human and mouse proteins is not permitted. Instead, "mouse" or "human" should be inserted before the relevant protein symbol in cases where it is necessary to distinguish between human and mouse proteins. (This protocol extends to proteins of all other organisms.)

Authors must use SI units and follow the guidelines for abbreviations and symbols of the IUPAC-IUBMB Joint Commission on Biochemical Nomenclature (External link http://www.chem.qmw.ac.uk/iupac/jcbn/).

GenBank

DNA sequences and GenBank accession numbers. Authors wishing to enable other scientists to use the accession numbers cited in their papers via links to these sources should type this information in the following manner: For each and every accession number cited in an article, authors should type the accession number in bold, underlined text. Letters in the accession number should always be capitalized (see example below). This combination of letters and format will enable the typesetter to recognize the relevant texts as accession numbers and add the required link to GenBank sequences. Example: GenBank accession nos. AI631510 , AI631511 , AI632198 , and BF223228 ), a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048 ), and a T-cell lymphoma (GenBank accession no. AA361117 ).

Authors are encouraged to check accession numbers used very carefully. An error in a letter or number can result in a dead link. In the final version of the printed article, the accession number text will not appear bold or underlined. In the final version of the electronic copy, the accession number text will be linked to the appropriate source in the NCBI databases, enabling readers to go directly to that source from the article.

Math formulae

Present simple formulae in the line of normal text where possible and use the solidus (/) instead of a horizontal line for small fractional terms, e.g., X/Y. In principle, variables are to be presented in italics. Powers of e are often more conveniently denoted by exp. Number consecutively any equations that have to be displayed separately from the text (if referred to explicitly in the text).

Footnotes

Footnotes should be used sparingly. Number them consecutively throughout the article, using superscript Arabic numbers. Many wordprocessors build footnotes into the text, and this feature may be used. Should this not be the case, indicate the position of footnotes in the text and present the footnotes themselves separately at the end of the article. Do not include footnotes in the Reference list.
Table footnotes
Indicate each footnote in a table with a superscript lowercase letter.

Electronic artwork

General points
• Make sure you use uniform lettering and sizing of your original artwork.
• Save text in illustrations as "graphics" or enclose the font.
• Only use the following fonts in your illustrations: Arial, Courier, Times, Symbol.
• Number the illustrations according to their sequence in the text.
• Use a logical naming convention for your artwork files.
• Provide captions to illustrations separately.
• Produce images near to the desired size of the printed version.
• Submit each figure as a separate file.

A detailed guide on electronic artwork is available on our website:
External link http://www.elsevier.com/artworkinstructions
You are urged to visit this site; some excerpts from the detailed information are given here.
Formats
Regardless of the application used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):
EPS: Vector drawings. Embed the font or save the text as "graphics".
TIFF: color or grayscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications please supply "as is".
Please do not:
• Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document;
• Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low;
• Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.

Color artwork

Please make sure that artwork files are in an acceptable format (TIFF, EPS or MS Office files) and with the correct resolution. If, together with your accepted article, you submit usable color figures then Elsevier will ensure, at no additional charge, that these figures will appear in color on the Web (e.g., ScienceDirect and other sites) regardless of whether or not these illustrations are reproduced in color in the printed version. For color reproduction in print, you will receive information regarding the costs from Elsevier after receipt of your accepted article. Please indicate your preference for color in print or on the Web only. For further information on the preparation of electronic artwork, please see External link http://www.elsevier.com/artworkinstructions.
Please note: Because of technical complications which can arise by converting color figures to "gray scale" (for the printed version should you not opt for color in print) please submit in addition usable black and white versions of all the color illustrations.

Figure captions

Ensure that each illustration has a caption. Supply captions separately, not attached to the figure. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.

Tables

Number tables consecutively in accordance with their appearance in the text. Place footnotes to tables below the table body and indicate them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that the data presented in tables do not duplicate results described elsewhere in the article.

References

Citation in text

Please ensure that every reference cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be given in full. Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the text. If these references are included in the reference list they should follow the standard reference style of the journal and should include a substitution of the publication date with either "Unpublished results" or "Personal communication" Citation of a reference as "in press" implies that the item has been accepted for publication.

Web references

As a minimum, the full URL should be given. Any further information, if known (DOI, author names, dates, reference to a source publication, etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired, or can be included in the reference list.

References in a special issue

Please ensure that the words 'this issue' are added to any references in the list (and any citations in the text) to other articles in the same Special Issue.

Reference style

Text: Indicate references by number(s) in square brackets in line with the text. The actual authors can be referred to, but the reference number(s) must always be given.
Example: "..... as demonstrated [3,6]. Barnaby and Jones [8] obtained a different result ...."
List: Number the references (numbers in square brackets) in the list in the order in which they appear in the text.
Examples:
Reference to a journal publication:
[1] J. van der Geer, J.A.J. Hanraads, R.A. Lupton, The art of writing a scientific article, J. Sci. Commun. 163 (2000) 51-59.
Reference to a book:
[2] W. Strunk Jr., E.B. White, The Elements of Style, third ed., Macmillan, New York, 1979.
Reference to a chapter in an edited book:
[3] G.R. Mettam, L.B. Adams, How to prepare an electronic version of your article, in: B.S. Jones, R.Z. Smith (Eds.), Introduction to the Electronic Age, E-Publishing Inc., New York, 1999, pp. 281-304.

Journal abbreviations source

Journal names should be abbreviated according to
Index Medicus journal abbreviations: External link http://www.nlm.nih.gov/tsd/serials/lji.html;
List of serial title word abbreviations: External link http://www.issn.org/2-22661-LTWA-online.php;
CAS (Chemical Abstracts Service): External link http://www.cas.org/sent.html.

Supplementary material

Elsevier accepts electronic supplementary material to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect: External link http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please ensure that data are provided in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. Video files: please supply 'stills' with your files: you can choose any frame from the video or make a separate image. These will be used instead of standard icons and will personalize the link to your supplementary information. For more detailed instructions please visit our artwork instruction pages at External link http://www.elsevier.com/artworkinstructions.

Submission checklist

It is hoped that this list will be useful during the final checking of an article prior to sending it to the journal's Editor for review. Please consult this Guide for Authors for further details of any item.
Ensure that the following items are present:
One Author designated as corresponding Author:
• E-mail address
• Full postal address
• Telephone and fax numbers
All necessary files have been uploaded
• Keywords
• All figure captions
• All tables (including title, description, footnotes)
Further considerations
• Manuscript has been "spellchecked" and "grammar-checked"
• References are in the correct format for this journal
• All references mentioned in the Reference list are cited in the text, and vice versa
• Permission has been obtained for use of copyrighted material from other sources (including the Web)
• color figures are clearly marked as being intended for color reproduction on the Web (free of charge) and in print or to be reproduced in color on the Web (free of charge) and in black-and-white in print
• If only color on the Web is required, black and white versions of the figures are also supplied for printing purposes
For any further information please visit our customer support site at External link http://epsupport.elsevier.com.

Additional Information

Cover art. Authors submitting a manuscript for consideration may also submit color figures for exclusive use as cover illustrations. These figures do not need to relate to the manuscript being submitted, but should relate to the larger scope and focus of Genomics. Submit art in electronic form (TIFF and EPS files only). A short (one-line) legend should accompany each figure.

AFTER ACCEPTANCE

Use of the Digital Object Identifier

The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. The correct format for citing a DOI is shown as follows (example taken from a document in the journal Physics Letters B):
doi:10.1016/j.physletb.2003.10.071
When you use the DOI to create URL hyperlinks to documents on the web, they are guaranteed never to change.

Proofs

One set of page proofs (as PDF files) will be sent by e-mail to the corresponding author (if we do not have an e-mail address then paper proofs will be sent by post) or, a link will be provided in the e-mail so that authors can download the files themselves. Elsevier now provides authors with PDF proofs which can be annotated; for this you will need to download Adobe Reader version 7 (or higher) available free from External link http://www.adobe.com/products/acrobat/readstep2.html. Instructions on how to annotate PDF files will accompany the proofs (also given online). The exact system requirements are given at the Adobe site: External link http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win.
If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and return them to Elsevier in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then mark the corrections and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail, or by post. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor. We will do everything possible to get your article published quickly and accurately. Therefore, it is important to ensure that all of your corrections are sent back to us in one communication: please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of your article if no response is received.

Offprints

The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail. The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use. Additional paper offprints can be ordered by the authors. An order form with prices will be sent to the corresponding author.

Additional Information

US National Institutes of Health (NIH) voluntary posting (" Public Access") policy

Elsevier facilitates author response to the NIH voluntary posting request (referred to as the NIH "Public Access Policy"; see External link http://www.nih.gov/about/publicaccess/index.htm) by posting the peer-reviewed author's manuscript directly to PubMed Central on request from the author, 12 months after formal publication. Upon notification from Elsevier of acceptance, we will ask you to confirm via e-mail (by e-mailing us at NIHauthorrequest@elsevier.com) that your work has received NIH funding and that you intend to respond to the NIH policy request, along with your NIH award number to facilitate processing. Upon such confirmation, Elsevier will submit to PubMed Central on your behalf a version of your manuscript that will include peer-review comments, for posting 12 months after formal publication. This will ensure that you will have responded fully to the NIH request policy. There will be no need for you to post your manuscript directly with PubMed Central, and any such posting is prohibited.

AUTHOR INQUIRIES

For inquiries relating to the submission of articles (including electronic submission where available) please visit this journal's homepage. You can track accepted articles at External link http://www.elsevier.com/trackarticle and set up e-mail alerts to inform you of when an article's status has changed. Also accessible from here is information on copyright, frequently asked questions and more. Contact details for questions arising after acceptance of an article, especially those relating to proofs, will be provided by the publisher.
 
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