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EXPERIMENTAL AND MOLECULAR PATHOLOGY

Guide for Authors

Experimental and Molecular Pathology presents original articles on disease processes in relation to structural and biochemical alterations in mammalian tissues and fluids and on the application of newer techniques of molecular biology to problems of pathology in humans and other animals. The journal has a broad scope, publishing both cellular- and molecular-level research and giving additional special impetus to molecular diagnostics and to immunopathology. Among the subjects targeted for major emphasis are atherosclerosis, cell receptors, carcinogenesis, complex infectious diseases, cytogenetics, flow cytometric analysis, hemostasis and thrombosis, cellular injury, oncogenes, pathogenesis of infection, tumor immunology, immunopathology, transplantation biology, macrophages, and cytokines, among other research topics. The journal also publishes selected interpretive synthesis reviews by bench-level investigators working at the cutting edge of contemporary research in pathology. In addition, special thematic issues present original research reports that unravel some of nature's most jealously guarded secrets on the pathologic basis of disease.

Submission of manuscripts. Submission to this journal proceeds totally online. Use the following guidelines to prepare your article. Via the Elsevier Editorial System page of this journal (http://ees.elsevier.com/emp/) you will be guided stepwise through the creation and uploading of the various files. The system automatically converts source files to a single Adobe Acrobat PDF version of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail and via the author's homepage, removing the need for a hard-copy paper trail.

There are no submission fees or page charges. Each manuscript should be accompanied by a letter outlining the basic findings of the paper and their significance.

Manuscripts must be written in concise, grammatical English. Authors who require information about language editing and copyediting services pre- and post-submission should visit http://www.elsevier.com/locate/languagepolishing or contact authorsupport@elsevier.com for more information. Please note Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside vendors through our services or in any advertising. For more information please refer to our Terms and Conditions at http://www.elsevier.com/termsandconditions.

Manuscripts are accepted for review with the understanding that no substantial portion of the study has been published or is under consideration for publication elsewhere and that its submission for publication has been approved by all of the authors and by the institution where the work was carried out; further, that any person cited as a source of personal communications has approved such citation. Written authorization may be required at the editor's discretion. Articles and any other material published in Experimental and Molecular Pathology represent the opinions of the author(s) and should not be construed to reflect the opinions of the editor(s) and the publisher. Manuscripts that do not meet the general criteria or standards for publication in Experimental and Molecular Pathology will be immediately returned to the authors, without detailed review.

Upon acceptance of an article, authors will be asked to sign a "Journal Publishing Agreement" (for more information on this and copyright see External link http://www.elsevier.com/copyright). Acceptance of the agreement will ensure the widest possible dissemination of information. An e-mail (or letter) will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.

If material from other copyrighted works is included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: contact Elsevier Global Rights Department, P.O. Box 800, Oxford OX5 1DX, UK; phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: permissions@elsevier.com.

Conflict of interest.Experimental and Molecular Pathology requires full disclosure of all potential conflicts of interest. At the end of the manuscript text (and in the cover letter of the manuscript), under a subheading "Conflict of Interest statement", all authors must disclose any financial and personal relationships with other people or organisations that could inappropriately influence (bias) their work. If there are no conflicts of interest, the authors should state, "The authors declare that there are no conflicts of interest." Signed copies of the Experimental and Molecular Pathology Conflict of Interest policy form are required upon submission. The Conflict of Interest policy form can be downloaded here. In order to minimize delays, we strongly advise that the signed copies of these statements are prepared before you submit your manuscript. The corresponding author is responsible for sharing this document with all co-authors. Each and every co-author must sign an individual disclosure form. The corresponding author is responsible for uploading their form and those of their co-authors.

US National Institutes of Health (NIH) voluntary posting ("Public Access") policy. Elsevier facilitates author response to the NIH voluntary posting request (referred to as the NIH "Public Access Policy"; see http://www.nih.gov/about/publicaccess/index.htm) by posting the peer-reviewed author's manuscript directly to PubMed Central on request from the author, 12 months after formal publication. Upon notification from Elsevier of acceptance, we will ask you to confirm via e-mail (by e-mailing us at NIHauthorrequest@elsevier.com) that your work has received NIH funding and that you intend to respond to the NIH policy request, along with your NIH award number to facilitate processing. Upon such confirmation, Elsevier will submit to PubMed Central on your behalf a version of your manuscript that will include peer-review comments, for posting 12 months after formal publication. This will ensure that you will have responded fully to the NIH request policy. There will be no need for you to post your manuscript directly with PubMed Central, and any such posting is prohibited.

Preparation of manuscripts. All abbreviations, chemical names, and journal names should follow the style of Chemical Abstracts Service Source Index. Use generic names of chemicals wherever possible. Proprietary names and trademarks should appear only to identify the source of the chemical and subsequently only the generic name should be used. All abbreviations should be unpunctuated. A useful writing guide is the "CBE Style Manual" published by the Council of Biology Editors.

Manuscripts should be double-spaced throughout with 1-inch margins on all sides. Pages should be numbered consecutively and organized as follows:

The title page (p. 1) should contain the article title, authors' names and complete affiliations, footnotes to the title, and the address for manuscript correspondence (including e-mail address and telephone and fax numbers). The title should be limited to 15 words or 80 characters.

The abstract (p. 2) must be a single paragraph that summarizes the main findings of the paper in 150-200 words. After the abstract a list of up to 10 keywords that will be useful for indexing or searching should be included.

The Introduction should be as concise as possible, without subheadings.

Materials and methods should be sufficiently detailed to enable the experiments to be reproduced.

Results and discussion may be combined and may be organized into subheadings.

Acknowledgments should be brief and should precede the references.

References should be cited in the text by author's name and year of publication in parentheses. Journal names should follow the style of Chemical Abstracts Service Source Index. Only articles that have been published or are in press should be included in the references. Unpublished results or personal communications should be cited as such in the text. References should be listed alphabetically. Please note the following examples:

Hagag, N., Viola, M.V., 1993. Chromosome Microdissection and Cloning: A Practical Guide. Academic Press, San Diego.

Reichert, U., Michel, S., Schmidt, R., 1993. The cornified envelope: a key structure of terminally differentiating keratinocytes. In: Darmon, M., Blumenberg, M. (Eds.),Molecular Biology of the Skin: The Keratinocyte. Academic Press, San Diego, pp. 107-150.

Wali, A., Strayer, D.S., 1999. Comparative effects of virulent and avirulent poxviruses on cell cycle progression. Exp. Mol. Pathol. 66, 31-38.

References in foreign languages should appear in the language of the original paper.

Figures should be understandable even without reading the text. Every figure should have a legend. Number figures consecutively with Arabic numerals. Please visit our Web site at http://www.elsevier.com/artworkinstructions for detailed instructions on preparing electronic artwork.

Color figures. Illustration in color in the printed issue can be accepted only if the authors defray the cost. However, if together with your accepted article you submit usable color figures, then Elsevier will ensure, at no additional charge, that these figures will appear in color on the Web (e.g., ScienceDirect and other sites) regardless of whether these illustrations are reproduced in color in the printed version. For color reproduction in print, you will receive information regarding the costs from Elsevier after receipt of your accepted article. Please note: Because of technical complications that can arise in converting color figures to "gray scale" (for the printed version should you not opt for color in print), please submit in addition usable black-and-white files corresponding to all the color illustrations.

Color figures for exclusive use as cover illustrations may be submitted by authors who are also submitting a manuscript for consideration. These figures do not need to relate to the manuscript being submitted but should relate to the larger scope and focus of Experimental and Molecular Pathology.

Tables should be numbered consecutively with Arabic numerals in order of appearance in the text. Type each table double-spaced on a separate page with a short descriptive title typed directly above and with essential footnotes below.

Preparation of supplementary material. Supplementary files offer additional possibilities for publishing supporting applications, movies, animation sequences, high-resolution images, background datasets, sound clips, and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect (http://www.sciencedirect.com). To ensure that your submitted material is directly usable, please provide the data in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. Please note, however, that supplementary material will not appear in the printed journal. For more detailed instructions, please visit http://www.elsevier.com/artworkinstructions.

PDF proofs will be sent by e-mail to the corresponding author. To avoid delay in publication, only necessary changes should be made, and proofs should be returned promptly.

Author inquiries. Register for free to receive email updates from the article tracking service at External link http://www.elsevier.com/trackarticle The article tracking service also provides the facility to set up e-mail alerts to inform you of when an article's status has changed, as well as detailed artwork guidelines, copyright information, frequently asked questions, and more. Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided after registration of an article for publication.
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