As the average human life expectancy has increased, so too has the impact of ageing and age-related disease on
our society. Ageing research is now the focus of thousands of laboratories that include leaders in the areas of genetics, molecular and
cellular biology, biochemistry, and behaviour. Ageing Research Reviews (ARR) covers the trends in this field. It is designed to fill
a large void, namely, a source for critical reviews and viewpoints on emerging findings on mechanisms of ageing and age-related disease.
Rapid advances in understanding of mechanisms that control cellular proliferation, differentiation and survival are leading to new insight
into the regulation of ageing. From telomerase to stem cells to energy and oxyradical metabolism, this is an exciting new era in the
multidisciplinary field of ageing research. The cellular and molecular underpinnings of manipulations that extend lifespan, such as caloric
restriction, are being identified and novel approaches for preventing age-related diseases are being developed. ARR publishes articles
on focussed topics selected from the broad field of ageing research, with an emphasis on cellular and molecular mechanisms of the aging
process and age-related diseases such as cancer, cardiovascular disease, diabetes and neurodegenerative disorders. Applications of basic
ageing research to lifespan extension and disease prevention are also covered in this journal.
SUBMISSION OF ARTICLES
Online manuscript submission
Authors should submit an electronic copy of their paper only, hard copies and disks are not
accepted. To submit online, go to http://ees.elsevier.com/arr
•Select the 'Submit paper' option.
•Follow prompts
online. Please note that at each stage of the submission process it is possible to go back a step, save the submission to continue later,
or remove/change any information already entered.
•The submission system will generate a PDF file to be used for the reviewing
process.
•You will receive confirmation of your submission and further progress of your paper at every stage of its review
period thereafter, via email.
Preparation of manuscripts
Manuscripts should be written in English. We accept most wordprocessing
formats, but Word, WordPerfect or LaTeX is preferred. Always keep a backup copy of the electronic file for reference and safety. Save
your files using default extension of the programme used.
Title page
The full name of the author(s) academic or professional
affiliations, and addresses should be included on the title page. The name and complete address of the person to whom proofs are to be
sent must be given. Include Telephone number, Fax number and E-mail address on the title page.
Abstract
The article
should start with an abstract of approximately 100-200 words.
Key words
The list of 3-6 key words necessary for correct
indexing and subsequent retrieval must be submitted with the manuscript. In the event that key words are not supplied editorial discretion
will be exercised in introducing appropriate words.
Headings
The manuscript should be divided in: 1. Introduction; 2.
Materials and methods; 3. Results; 4. Discussion; Acknowledgements; References; Tables; Figure legends and Figures. Both sections and
their subdivisions should be numbered (2.1., 2.2., 2.3. etc).
Tables
Tables should be typed in double spacing on separate
sheets and each provided with a suitable heading. Tables should be numbered separately in Arabic numerals (Table 1, 2 etc.)
Colour
Figures
If together with your accepted article, you submit usable colour figures, then Elsevier will ensure, at no additional
charge, that these figures will appear in colour on the Web (e.g., ScienceDirect and other sites) regardless of whether these illustrations
are reproduced in colour in the printed version. For colour reproduction in print, you will receive information regarding the costs from
Elsevier after receipt of your accepted article. For further information on the preparation of electronic artwork, please see http://www.elsevier.com/artworkinstructions
[Please note: Because of technical complications that can arise in converting colour figures to "grey scale" (for the printed version
should you not opt for colour in print), please submit in addition usable black-and-white files corresponding to all the colour illustrations.
References
All publications cited in the text should be presented in a list of references following the text of the manuscript.
The manuscript should be carefully checked to ensure that the spelling of author's names and dates are exactly the same in the text as
in the reference list.
In the text refer to the name of the author(s) (without initial) followed by the year of publication. If reference
is made in the text to a publication written by more than two authors the name of the first author should be used followed by `et al.'.
This indication, however, should never be used in the list of references. In this list names of first author and co-authors should be
mentioned. References cited together in the text should be arranged chronologically. The list of references should be arranged alphabetically
on author's names, and chronologically per author. If an author's name in the list is also mentioned with co-authors the following order
should by used: publications of the single author, arranged according to publication dates - publications of the same author with one
co-author - publications of the author with more than one co-author. Publications by the same author(s) in the same year should be listed
as 1974a, 1974b, etc.
Use the following system for arranging your references: a. For periodicals
Paivio. A., Jansen,
B., Becker, L.J., 1975. Comparisons through the mind's eye. Cognition 37, 635-647. b. For edited symposia, special issues, etc.
published in a periodical.
Benzie, J.A.H., Ballment, E., Frusher, S., 1993. Genetic structure of Penaeusmonodon in Australia:
concordant results from mtDNA and allozymes. In: Gall, G.A.F., Chen, H. (Eds.), Genetics in Aquaculture IV. Proceedings of the Fourth
International Symposium, 29 April-3 May 1991, Wuhan, China. Aquaculture, 111, 89-93. c. For books
Strunk Jr., W., White,
E.B., 1979. The Elements of Style, 3rd ed. MacMillan, New York. d. For multi-author books
Gurman, A.S., Kniskern, D.P.,
1981. Family therapy outcome research: knowns and unknowns. In: Gurman, A.S., Kniskern, D.P. (Eds.). Handbook of Family Therapy. Brunner/Maazel,
New York, pp. 742-775.
Abbreviate the titles of periodicals mentioned in the list of references according to the International List
of Periodical Title Word Abbreviations. In the case of publications in any language other than English, the original title is to be retained.
However, the titles of publications in non-Latin alphabets should be transliterated, and a notation such as '(in Russian)' or '(in Greek,
with English abstract)' should be added. Work accepted for publication but not yet published should be referred to as 'in press'.
References
concerning unpublished data and 'personal communications' should not be cited in the reference list but may be mentioned in the text.
Supplementary material
Electronic supplementary material is now accepted to support and enhance your scientific research.
Supplementary files offer the author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution
images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version
of your article in Elsevier web products, including ScienceDirect: http://www.sciencedirect.com. In order to ensure that
your submitted material is directly usable, please ensure that data is provided in one of our recommended file formats. Authors should
submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For more
detailed instructions please visit our Corporate Website at http://www.elsevier.com/authors.
Ethics
When human subjects are used, manuscripts must be accompanied by a statement that the experiments were undertaken with the understanding
and written consent of each subject, with the approval of the appropriate local ethics committee, and in compliance with national legislation
and the Code of Ethical Principles for Medical Research Involving Human Subjects of the World Medical Association (Declaration of Helsinki)
[http://www.wma.net/e/policy/b3.htm]. When experimental animals are used, the materials and methods section must clearly
indicate that adequate measures were taken to minimise pain or discomfort, and that the experiments were conducted in accordance with
international standards on animal welfare as well as being compliant with local and national regulations. Studies are expected to be
compliant with minimal standards as defined by the European Communities Council Directive of 24 November 1986 (86/609/EEC)
Copyright
Upon acceptance of an article, authors will be asked to Transfer copyright. This transfer will ensure the widest possible dissemination
of information.
If material from other copyrighted works is included, the author(s) must obtain written permission from the copyright
owners and credit the source(s) in the article. Elsevier has pre-printed forms for use by authors in these cases: contact Elsevier Rights
Department, P.O. Box 800, Oxford, OX5 1DX, UK, phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: permissions@elsevier.com.
Requests may also be completed online via the Elsevier home page (http://www.elsevier.com/locate/permissions).
Proofs
One set of page proofs in PDF format will be sent by e-mail to the corresponding author (if we do not have an e-mail address then paper
proofs will be sent by post). Elsevier now sends PDF proofs which can be annotated; for this you will need to download Adobe Reader version
7 available free from
http://www.adobe.com/products/acrobat/readstep2.html. Instructions on how to annotate PDF files will
accompany the proofs. The exact system requirements are given at the Adobe site: http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win
If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and return
to Elsevier in an e-mail.
Please list your corrections quoting line number. If, for any reason, this is not possible, then mark the corrections
and any other comments (including replies
to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail,
or by post.
Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures.
Significant changes to the article
as accepted for publication will only be considered at this stage with permission from the Editor.
We will do everything possible to get your article published
quickly and accurately. Therefore, it is important to ensure that all of
your corrections are sent back to us in one communication: please check carefully before
replying, as inclusion of any subsequent corrections
cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with
the publication of your article
if no response is received.
Author enquiries
For enquiries relating to the submission of articles, please visit this
journal's homepage at http://www.elsevier.com/locate/arr. You can track accepted articles at http://www.elsevier.com/trackarticle
and set up e-mail alerts to inform you of when an article's status has changed, as well as copyright information, frequently asked questions
and more.
Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided
after registration of an article for publication.
Offprints
The corresponding author, at no cost, will be provided with
a PDF ?le of the article via e-mail or, alternatively, 25 free paper offprints. The PDF ?le is a watermarked version of the published
article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use. Additional
reprints may be ordered on the reprint order form which will accompany the proofs sent to the author. Reprints may also be obtained after
publication of the paper at a somewhat higher cost.
US National Institutes of Health (NIH) voluntary posting ("Public Access")
policy.
Elsevier facilitates author response to the NIH voluntary posting request (referred to as the NIH "Public Access Policy";
see http://www.nih.gov/about/publicaccess/index.htm) by posting the peer-reviewed author's manuscript directly to PubMed
Central on request from the author, 12 months after formal publication. Upon notification from Elsevier of acceptance, we will ask you
to confirm via e-mail (by e-mailing us at NIHauthorrequest@elsevier.com) that your work has received NIH funding and that
you intend to respond to the NIH policy request, along with your NIH award number to facilitate processing. Upon such confirmation, Elsevier
will submit to PubMed Central on your behalf a version of your manuscript that will include peer-review comments, for posting 12 months
after formal publication. This will ensure that you will have responded fully to the NIH request policy. There will be no need for you
to post your manuscript directly with PubMed Central, and any such posting is prohibited.
Disclaimer
Whilst every effort
is made by the publishers and editorial board to see that no inaccurate or misleading data, opinion or statement appears in this journal,
they wish to make it clear that the data and opinions appearing in the articles and advertisements herein are the sole responsibility
of the contributor or advertiser concerned. Accordingly, the publishers, the editorial board and editor and their respective employees,
officers and agents accept no responsibility or liability whatsoever for the consequences of any inaccurate or misleading data, opinion
or statement.
