Guide for Authors
Affiliated with the
American Society for Matrix Biology
Affiliated with the
International Society for Matrix Biology
!!! Important information for NIH authors !!!
Matrix Biology publishes Regular Research Papers, Brief Reports, Mini Reviews, Landmark
Essays, Full Length Reviews and Announcements. The section Types of Papers describes the conditions each of these submission types should
meet.
Papers that do not conform to the general criteria for publication in
Matrix Biology will be returned immediately
to authors to avoid unnecessary delay in submission elsewhere.
The decision of the Editor is final; the Editor cannot enter into
correspondence about a paper that is considered unsuitable for publication.
Revisions should be submitted within 90 days. If we do
not receive your revision within 120 days, your paper will be withdrawn and removed from the system.
Types of papers
Regular Research Papers
Matrix Biology will review for publication studies utilizing
most scientific technologies including molecular biology, cell biology, immunochemistry, structural biology, computational biology, theoretical
biology, and macromolecular chemistry where the subject is extra cellular matrix or is substantially related to matrix and its biological
role. The journal will publish articles that are scientifically rigorous, complete within some logical framework, address molecular or
cellular mechanisms, and present results that are timely and above average significance. Methods without application to a significant
project and data on a new species or system similar to results already in the literature will not be accepted as a regular paper but
may be suitable as a Short Note.
Brief Reports
Matrix Biology will also review for publication brief reports that meet
the same standards of quality and field of interest as regular papers but have a narrower scope and more focused interest. Examples are:
DNA sequence from a new species of special interest where the sequence from another species is in the literature; a probe, assay or method
that is particularly novel and useful; a new mutation that broadens understanding in a genetic disease where other mutations are known;
and brief results of more than usual interest that will be followed by a more detailed study.
Mini Reviews
The aims of
the reviews are to: (a) summarize the general concepts in the field; (b) provide a brief summary of the new information in the field;
and (c) define unresolved questions and disagreements about currently available data. The mini-reviews will be of two different types,
single mini-reviews that will summarize some new and important discovery in the field, and cluster mini-reviews on a topic that has been
under investigation for some time. To ensure that the mini-reviews reflect a consensus to the scientists in the field, they will be published
in one or two issues as series of articles consisting of (a) an Introductory Review by a Special Editor selected for the series; (b)
two or more specialized reviews from two or more additional experts in the field and (c) Letters-to-the-Editor by additional experts
in the field who will be invited to comment or volunteer to comment on specific issues raised in the reviews.
Landmark Essays
Full Length Reviews
These are invited comprehensive summaries and analyses of topics that have been under investigation
for some time.
Announcements
Announcements of national or international meetings may be published in Matrix Biology.
Contact details for submission
Manuscripts for Matrix Biology should be submitted via the journal's online
submission page at
http://ees.elsevier.com/matbio.
For all technical queries please consult our help site at
http://epsupport.elsevier.com/.
Here you will be able to learn more about the online submission system via interactive tutorials, explore a range of online submission
solutions via our knowledgebase, and find answers to frequently asked questions. You will also find our 24/7 support contact details
should you need any assistance from one of our customer service representatives.
For questions on the submission and reviewing process,
please contact the Editorial Office at
bjorn_olsen@hms.harvard.edu, or, in case of a Review, the Reviews Editor, at
Renato.Iozzo@mail.tju.edu.
Editor-in-Chief: Matrix Biology Office, Bjorn R. Olsen, Editor-in-Chief, Harvard School of Dental Medicine, Department of Oral
and Developmental Biology, 188 Longwood Avenue, Boston, MA 02115, USA, Tel: (+1) 617 432 2359, Fax: (+1) 617 432 0638, e-mail:
bjorn_olsen@hms.harvard.edu.
Reviews Editor: Renato Iozzo, Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, 249 Jefferson
Alumni Hall, 1020 Locust Street, Philadelphia, PA, USA, Fax:(+1)215 923 7969, e-mail:
Renato.Iozzo@mail.tju.edu
Ethics in Publishing
For information
on Ethics in Publishing and Ethical guidelines for journal publication see
http://www.elsevier.com/publishingethics and
http://www.elsevier.com/ethicalguidelines.
Conflict of interest
All
authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships
with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived
to influence, their work. See also
http://www.elsevier.com/conflictsofinterest.
Submission declaration
Submission of an article implies that the work described has not been published previously (except
in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication
elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was
carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without
the written consent of the copyright-holder.
Contributors
Each author is
required to declare his or her individual contribution to the article: all authors must have materially participated in the research
and/or article preparation, so roles for all authors should be described. The statement that all authors have approved the final article
should be true and included in the disclosure.
Copyright
Upon acceptance
of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more information on this and copyright see
http://www.elsevier.com/copyright).
Acceptance of the agreement will ensure the widest possible dissemination of information. An e-mail will be sent to the corresponding
author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this
agreement.
Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation
within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other
derivative works, including compilations and translations (please consult
http://www.elsevier.com/permissions). If excerpts
from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s)
in the article. Elsevier has preprinted forms for use by authors in these cases: please consult
http://www.elsevier.com/permissions.
Retained author rights
As an author you (or your employer or institution) retain certain rights; for details
you are referred to:
http://www.elsevier.com/authorsrights.
Role of the
funding source
You are requested to identify who provided financial support for the conduct of the research and/or preparation
of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation
of data; in the writing of the report; and in the decision to submit the paper for publication. If the funding source(s) had no such
involvement then this should be stated. Please see
http://www.elsevier.com/funding.
Funding body agreements and policies
Elsevier has established agreements and developed policies to allow authors whose
articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions
of their grant awards. To learn more about existing agreements and policies please visit
http://www.elsevier.com/fundingbodies.
Language and language services
Please write your text in good English (American or British usage is accepted,
but not a mixture of these). Authors who require information about language editing and copyediting services pre- and post-submission
please visit
http://www.elsevier.com/languagepolishing or our customer support site at
http://epsupport.elsevier.com
for more information. Please note Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside
vendors through our services or in any advertising. For more information please refer to our Terms & Conditions:
http://www.elsevier.com/termsandconditions.
Submission
Submission to this journal proceeds totally online and you will be guided stepwise through
the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is
used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the
review process, these source files are needed for further processing after acceptance. All correspondence, including notification of
the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.
Referees
Please submit, with the manuscript, the names, addresses and e-mail addresses of 3 potential referees.
Note that the editor retains the sole right to decide whether or not the suggested reviewers are used.
Use of wordprocessing software
It
is important that the file be saved in the native format of the wordprocessor used. The text should be in single-column format. Keep
the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular,
do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts
etc. Do not embed "graphically designed" equations or tables, but prepare these using the wordprocessor's facility. When preparing tables,
if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs,
not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also
the Guide to Publishing with Elsevier:
http://www.elsevier.com/guidepublication). Do not import the figures into the text
file but, instead, indicate their approximate locations directly in the electronic text and on the manuscript. See also the section on
Electronic illustrations.
To avoid unnecessary errors you are strongly advised to use the "spell-check" and "grammar-check" functions
of your wordprocessor.
Article structure
Subdivision - numbered sections
Divide your article into clearly defined and numbered sections. Subsections should
be numbered 1.1 (then 1.1.1, 1.1.2, ...), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for
internal cross-referencing: do not just refer to "the text". Any subsection may be given a brief heading. Each heading should appear
on its own separate line.
Introduction
State the objectives of the
work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.
Results
Results should be clear and concise.
Discussion
This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often
appropriate. Avoid extensive citations and discussion of published literature.
Essential
title page information
•
Title.
Concise and informative. Titles are often used in information-retrieval
systems. Avoid abbreviations and formulae where possible.
•
Author names and affiliations.
Where the family name
may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work
was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in
front of the appropriate address. Provide the full postal address of each affiliation, including the country name, and, if available,
the e-mail address of each author.
•
Corresponding author.
Clearly indicate who will handle correspondence at
all stages of refereeing and publication, also post-publication.
Ensure that telephone and fax numbers (with country and area code)
are provided in addition to the e-mail address and the complete postal address.
•
Present/permanent address.
If an author has moved since the work described in the article was done, or was visiting at the time, a "Present address" (or "Permanent
address") may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained
as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.
Abstract
A concise and factual abstract is required. The abstract should state briefly the purpose of the research, the
principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone.
For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard or uncommon
abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself.
An abstract is not required for Landmark Essays.
Keywords
Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms
and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations: only abbreviations firmly established in the
field may be eligible. These keywords will be used for indexing purposes.
Abbreviations
Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations
that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of
abbreviations throughout the article.
Acknowledgements
Collate acknowledgements
in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote
to the title or otherwise. List here those individuals who provided help during the research (e.g., providing language help, writing
assistance or proof reading the article, etc.).
Math formulae
Present
simple formulae in the line of normal text where possible and use the solidus (/) instead of a horizontal line for small fractional terms,
e.g., X/Y. In principle, variables are to be presented in italics. Powers of e are often more conveniently denoted by exp. Number consecutively
any equations that have to be displayed separately from the text (if referred to explicitly in the text).
Footnotes
Footnotes should be used sparingly. Number them consecutively throughout the article, using superscript
Arabic numbers. Many wordprocessors build footnotes into the text, and this feature may be used. Should this not be the case, indicate
the position of footnotes in the text and present the footnotes themselves separately at the end of the article. Do not include footnotes
in the Reference list.
Table footnotes
Indicate each footnote in a table with a superscript lowercase letter.
Artwork
Electronic artwork
General points
• Make sure you use uniform lettering and sizing of your original artwork.
• Save text in illustrations as "graphics"
or enclose the font.
• Only use the following fonts in your illustrations: Arial, Courier, Times, Symbol.
• Number
the illustrations according to their sequence in the text.
• Use a logical naming convention for your artwork files.
•
Provide captions to illustrations separately.
• Produce images near to the desired size of the printed version.
• Submit
each figure as a separate file.
A detailed guide on electronic artwork is available on our website:
http://www.elsevier.com/artworkinstructions
You are urged to visit this site; some excerpts from the detailed information are given here.
Formats
Regardless
of the application used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats
(note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):
EPS: Vector drawings.
Embed the font or save the text as "graphics".
TIFF: color or grayscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (color or grayscale): a
minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications
please supply "as is".
Please do not:
• Supply embedded graphics in your wordprocessor (spreadsheet, presentation)
document;
• Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low;
•
Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.
Color artwork
Please make sure that artwork files are in an acceptable format (TIFF, EPS or MS Office
files) and with the correct resolution. If, together with your accepted article, you submit usable color figures then Elsevier will ensure,
at no additional charge, that these figures will appear in color on the Web (e.g., ScienceDirect and other sites) regardless of whether
or not these illustrations are reproduced in color in the printed version.
For color reproduction in print, you will receive information
regarding the costs from Elsevier after receipt of your accepted article. Please indicate your preference for color in print or on
the Web only. For further information on the preparation of electronic artwork, please see
http://www.elsevier.com/artworkinstructions.
Please note: Because of technical complications which can arise by converting color figures to "gray scale" (for the printed version
should you not opt for color in print) please submit in addition usable black and white versions of all the color illustrations.
Figure captions
Ensure that each illustration has a caption. Supply captions separately, not attached
to the figure. A caption should comprise a brief title (
not on the figure itself) and a description of the illustration. Keep
text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.
Tables
Number tables consecutively in accordance with their appearance in the text. Place footnotes to tables below the
table body and indicate them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that
the data presented in tables do not duplicate results described elsewhere in the article.
References
Citation in text
Please ensure that every reference
cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be given in full.
Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the text. If these
references are included in the reference list they should follow the standard reference style of the journal and should include a substitution
of the publication date with either "Unpublished results" or "Personal communication" Citation of a reference as "in press" implies that
the item has been accepted for publication.
Web references
As a minimum,
the full URL should be given. Any further information, if known (DOI, author names, dates, reference to a source publication, etc.),
should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired,
or can be included in the reference list.
References in a special issue
Please ensure that the words 'this issue' are added to any references in the list (and any citations in the text) to other articles
in the same Special Issue.
Reference style
Text: All citations
in the text should refer to:
1.
Single author: the author's name (without initials, unless there is ambiguity) and the year
of publication;
2.
Two authors: both authors' names and the year of publication;
3.
Three or more authors:
first author's name followed by "et al." and the year of publication.
Citations may be made directly (or parenthetically). Groups
of references should be listed first alphabetically, then chronologically.
Examples: "as demonstrated (Allan, 1996a, 1996b, 1999;
Allan and Jones, 1995). Kramer et al. (2000) have recently shown ...."
List: References should be arranged first alphabetically
and then further sorted chronologically if necessary. More than one reference from the same author(s) in the same year must be identified
by the letters "a", "b", "c", etc., placed after the year of publication.
Examples:
Reference to a journal publication:
Van der Geer, J., Hanraads, J.A.J., Lupton, R.A., 2000. The art of writing a scientific article. J. Sci. Commun. 163, 51-59.
Reference
to a book:
Strunk Jr., W., White, E.B., 1979. The Elements of Style, third ed. Macmillan, New York.
Reference to a chapter in
an edited book:
Mettam, G.R., Adams, L.B., 1999. How to prepare an electronic version of your article, in: Jones, B.S., Smith , R.Z.
(Eds.), Introduction to the Electronic Age. E-Publishing Inc., New York, pp. 281-304.
Journal abbreviations source
Journal names should be abbreviated according to
Index Medicus journal abbreviations:
http://www.nlm.nih.gov/tsd/serials/lji.html;
List of serial title word abbreviations:
http://www.issn.org/2-22661-LTWA-online.php;
CAS (Chemical Abstracts Service):
http://www.cas.org/sent.html.
Supplementary
material
Elsevier accepts electronic supplementary material to support and enhance your scientific research. Supplementary
files offer the author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images,
background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of
your article in Elsevier Web products, including ScienceDirect:
http://www.sciencedirect.com. In order to ensure that your
submitted material is directly usable, please ensure that data are provided in one of our recommended file formats. Authors should submit
the material in electronic format together with the article and supply a concise and descriptive caption for each file. Video files:
please supply 'stills' with your files: you can choose any frame from the video or make a separate image. These will be used instead
of standard icons and will personalize the link to your supplementary information. For more detailed instructions please visit our artwork
instruction pages at
http://www.elsevier.com/artworkinstructions.
Submission
checklist
It is hoped that this list will be useful during the final checking of an article prior to sending it to the journal's
Editor for review. Please consult this Guide for Authors for further details of any item.
Ensure that the following items are
present:
One Author designated as corresponding Author:
• E-mail address
• Full postal address
• Telephone
and fax numbers
All necessary files have been uploaded
• Keywords
• All figure captions
• All tables (including
title, description, footnotes)
Further considerations
• Manuscript has been "spellchecked" and "grammar-checked"
•
References are in the correct format for this journal
• All references mentioned in the Reference list are cited in the text,
and vice versa
• Permission has been obtained for use of copyrighted material from other sources (including the Web)
•
Color figures are clearly marked as being intended for color reproduction on the Web (free of charge) and in print or to be reproduced
in color on the Web (free of charge) and in black-and-white in print
• If only color on the Web is required, black and white
versions of the figures are also supplied for printing purposes
For any further information please visit our customer support site
at
http://epsupport.elsevier.com.
Amino acid and nuclei sequences
Sequences should be computer printed using a monospace font and high quality printer. They should be assembled as a camera-ready
figure, not a table, so that the alignment can be maintained.
Use of the Digital Object Identifier
The Digital Object Identifier (DOI)
may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to
a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium
for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. The
correct format for citing a DOI is shown as follows (example taken from a document in the journal
Physics Letters B):
doi:10.1016/j.physletb.2003.10.071
When you use the DOI to create URL hyperlinks to documents on the web, they are guaranteed never to change.
Proofs
One set of page proofs (as PDF files) will be sent by e-mail to the corresponding author (if we do
not have an e-mail address then paper proofs will be sent by post) or, a link will be provided in the e-mail so that authors can download
the files themselves. Elsevier now provides authors with PDF proofs which can be annotated; for this you will need to download Adobe
Reader version 7 (or higher) available free from
http://www.adobe.com/products/acrobat/readstep2.html. Instructions on how
to annotate PDF files will accompany the proofs (also given online). The exact system requirements are given at the Adobe site:
http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win.
If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and
return them to Elsevier in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then
mark the corrections and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan
the pages and e-mail, or by post. Please use this proof only for checking the typesetting, editing, completeness and correctness of the
text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission
from the Editor. We will do everything possible to get your article published quickly and accurately. Therefore, it is important to ensure
that all of your corrections are sent back to us in one communication: please check carefully before replying, as inclusion of any subsequent
corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of
your article if no response is received.
Offprints
The corresponding author,
at no cost, will be provided with a PDF file of the article via e-mail or, alternatively, 25 free paper offprints. The PDF file is a
watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms
and conditions of use.
For inquiries relating to the
submission of articles (including electronic submission where available) please visit this journal's homepage. You can track accepted
articles at
http://www.elsevier.com/trackarticle and set up e-mail alerts to inform you of when an article's status has
changed. Also accessible from here is information on copyright, frequently asked questions and more. Contact details for questions arising
after acceptance of an article, especially those relating to proofs, will be provided by the publisher.
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