Guide for Authors
!!! Important information for NIH authors !!!
Cellular Signalling publishes full-length, original papers, written in a concise style,
that describe key, novel findings on all aspects of mechanisms, actions and structural components of cellular signalling systems. The
emphasis is on:
• effector systems, such as protein kinases, lipid signalling pathways, cyclic nucleotide signalling processes,
NO signalling and ion channels;
• the production, regulation, degradation and action of second messengers; the structure, regulation,
degradation and action of receptors;
• guanine nucleotide regulatory proteins;
• bio-informatic studies related to
cell signalling mechanisms;
• compartmentalisation/compartmentation of signalling systems;
• anchor/scaffold signalling
proteins;
• the effect of cellular signalling events on the functioning, growth and differentiation of cells in normal and pathological
states and also cellular oncogenes.
Within the scope of the journal, manuscripts dealing with biochemistry, protein structure, cell
biology, molecular biology, pharmacology, neurobiology, molecular endocrinology and molecular oncology are welcomed.
The journal
does not publish short reports.
Cellular Signalling will also publish Topical Reviews of some five thousand to eight thousand words.
In general, reviews will be solicited by the Editorial Board. However, intending contributors of unsolicited review articles can send
a brief summary of their proposed Topical Review to the Editorial Office for comment on its possible acceptability prior to submission.
Cellular Signalling will endeavour to give authors as rapid a decision as possible concerning the acceptability of their manuscript.
Final decisions concerning acceptability will be made both on the novelty of the work, its scientific content and appropriateness to
the remit of the journal.
Should Authors be requested by the Editor to revise the text, the revised version should be submitted within
eight weeks. After this period, the article will be regarded as a new submission.
Types
of paper
Cellular Signalling will accept:
• Full-length research papers
• Topical Reviews (5000-8000 words)
Contact details for submission
Manuscripts should be submitted to the journal's online submission and editorial
system,
http://ees.elsevier.com/cls.
For questions regarding the submission process, please look at
http://epsupport.elsevier.com.
For questions regarding the reviewing process, please contact the Editor-in-Chief: Miles D. Houslay, at
m.houslay@bio.gla.ac.uk,
the Editor: Nigel Pyne, at
n.j.pyne@strath.ac.uk, or one of the Co-Editors: George S. Baillie, at
G.Baillie@biolgla.ac.uk,
or Susan Pyne at
susan.pynes@strath.ac.uk, depending on who is handling your article.
Ethics in Publishing
For information
on Ethics in Publishing and Ethical guidelines for journal publication see
http://www.elsevier.com/publishingethics and
http://www.elsevier.com/ethicalguidelines.
Policy and ethics
The
work described in your article must have been carried out in accordance with
The Code of Ethics of the World Medical Association
(Declaration of Helsinki) for experiments involving humans http://www.wma.net/e/policy/b3.htm;
EC Directive 86/609/EEC
for animal experiments http://ec.europa.eu/environment/chemicals/lab_animals/legislation_en.htm;
Uniform Requirements
for manuscripts submitted to Biomedical journals http://www.icmje.org. This must be stated at an appropriate point
in the article.
Conflict of interest
All authors are requested to disclose
any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations
within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See
also
http://www.elsevier.com/conflictsofinterest.
Submission declaration
Submission of an article implies that the work described has not been published previously (except in the form of an abstract
or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication
is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted,
it will not be published elsewhere in the same form, in English or in any other language, without the written consent of the copyright-holder.
Contributors
Each author is required to declare his or her individual contribution to the article: all authors
must have materially participated in the research and/or article preparation, so roles for all authors should be described. The statement
that all authors have approved the final article should be true and included in the disclosure.
Copyright
Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more
information on this and copyright see
http://www.elsevier.com/copyright). Acceptance of the agreement will ensure the widest
possible dissemination of information. An e-mail will be sent to the corresponding author confirming receipt of the manuscript together
with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
Subscribers may reproduce tables of
contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher
is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations
(please consult
http://www.elsevier.com/permissions). If excerpts from other copyrighted works are included, the author(s)
must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use
by authors in these cases: please consult
http://www.elsevier.com/permissions.
Retained author rights
As an author you (or your employer or institution) retain certain rights; for details you are referred
to:
http://www.elsevier.com/authorsrights.
Role of the funding source
You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article
and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data;
in the writing of the report; and in the decision to submit the paper for publication. If the funding source(s) had no such involvement
then this should be stated. Please see
http://www.elsevier.com/funding.
Funding body agreements and policies
Elsevier has established agreements and developed policies to allow authors whose
articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions
of their grant awards. To learn more about existing agreements and policies please visit
http://www.elsevier.com/fundingbodies.
Language and language services
Please write your text in good English (American or British usage is accepted,
but not a mixture of these). Authors who require information about language editing and copyediting services pre- and post-submission
please visit
http://www.elsevier.com/languagepolishing or our customer support site at
http://epsupport.elsevier.com
for more information. Please note Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside
vendors through our services or in any advertising. For more information please refer to our Terms & Conditions:
http://www.elsevier.com/termsandconditions.
Submission
Submission to this journal proceeds totally online and you will be guided stepwise through
the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is
used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the
review process, these source files are needed for further processing after acceptance. All correspondence, including notification of
the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.
Referees
Please submit, with the manuscript, the names, addresses and e-mail addresses of 3 potential referees.
Note that the editor retains the sole right to decide whether or not the suggested reviewers are used.
Use of wordprocessing software
It
is important that the file be saved in the native format of the wordprocessor used. The text should be in single-column format. Keep
the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular,
do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts
etc. Do not embed "graphically designed" equations or tables, but prepare these using the wordprocessor's facility. When preparing tables,
if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs,
not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also
the Guide to Publishing with Elsevier:
http://www.elsevier.com/guidepublication). Do not import the figures into the text
file but, instead, indicate their approximate locations directly in the electronic text and on the manuscript. See also the section on
Electronic illustrations.
To avoid unnecessary errors you are strongly advised to use the "spell-check" and "grammar-check" functions
of your wordprocessor.
Article structure
Subdivision - numbered sections
Divide your article into clearly defined and numbered sections. Subsections should
be numbered 1.1 (then 1.1.1, 1.1.2, ...), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for
internal cross-referencing: do not just refer to "the text". Any subsection may be given a brief heading. Each heading should appear
on its own separate line.
Introduction
State the objectives of the
work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.
Material and methods
Provide sufficient detail to allow the work to be reproduced. Methods already
published should be indicated by a reference: only relevant modifications should be described.
Results
Results should be clear and concise.
Discussion
This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often
appropriate. Avoid extensive citations and discussion of published literature.
Conclusions
A short Conclusions section is to be presented and should be divided into specific points.
Essential title page information
•
Title.
Concise and informative. Titles are often
used in information-retrieval systems. Avoid abbreviations and formulae where possible.
•
Author names and affiliations.
Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses
(where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the
author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name,
and, if available, the e-mail address of each author.
•
Corresponding author.
Clearly indicate who will handle
correspondence at all stages of refereeing and publication, also post-publication.
Ensure that telephone and fax numbers (with country
and area code) are provided in addition to the e-mail address and the complete postal address.
•
Present/permanent
address.
If an author has moved since the work described in the article was done, or was visiting at the time, a "Present address"
(or "Permanent address") may be indicated as a footnote to that author's name. The address at which the author actually did the work
must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.
Abstract
A concise and factual abstract is required. The abstract should state briefly the purpose of the
research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able
to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard
or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself.
Keywords
Immediately after the abstract, provide a maximum of 6 keywords, using British spelling and avoiding
general and plural terms and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations: only abbreviations firmly
established in the field may be eligible. These keywords will be used for indexing purposes.
Abbreviations
Define abbreviations that are not standard in this field in a footnote to be placed on the first page of
the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the
footnote. Ensure consistency of abbreviations throughout the article.
Acknowledgements
Collate acknowledgements in a separate section at the end of the article before the references and do not, therefore, include
them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g.,
providing language help, writing assistance or proof reading the article, etc.).
Accession
numbers
Accession numbers are unique identifiers in bioinformatics allocated to nucleotide and protein sequences to allow
tracking of different versions of that sequence record and the associated sequence in a data repository [e.g., databases at the National
Center for Biotechnical Information (NCBI) at the National Library of Medicine ('GenBank') and the Worldwide Protein Data Bank]. There
are different types of accession numbers in use based on the type of sequence cited, each of which uses a different coding. Authors should
explicitly mention the
type of accession number together with the actual number, bearing in mind that an error in a letter or
number can result in a dead link in the online version of the article. Please use the following format: accession number type ID: xxxx
(e.g., MMDB ID: 12345; PDB ID: 1TUP). Note that in the final version of the
electronic copy, accession numbers will be linked
to the appropriate database, enabling readers to go directly to that source from the article.
Artwork
Electronic artwork
General points
•
Make sure you use uniform lettering and sizing of your original artwork.
• Save text in illustrations as "graphics" or enclose
the font.
• Only use the following fonts in your illustrations: Arial, Courier, Times, Symbol.
• Number the illustrations
according to their sequence in the text.
• Use a logical naming convention for your artwork files.
• Provide captions
to illustrations separately.
• Produce images near to the desired size of the printed version.
• Submit each figure
as a separate file.
A detailed guide on electronic artwork is available on our website:
http://www.elsevier.com/artworkinstructions
You are urged to visit this site; some excerpts from the detailed information are given here.
Formats
Regardless
of the application used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats
(note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):
EPS: Vector drawings.
Embed the font or save the text as "graphics".
TIFF: color or grayscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (color or grayscale): a
minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office applications
please supply "as is".
Please do not:
• Supply embedded graphics in your wordprocessor (spreadsheet, presentation)
document;
• Supply files that are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low;
•
Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.
Figure Captions
Ensure that each illustration has a caption. Supply captions separately, not attached to
the figure. A caption should comprise a brief title (
not on the figure itself) and a description of the illustration. Keep text
in the illustrations themselves to a minimum but explain all symbols and abbreviations used.
All colour artwork will appear online
free of charge. (The printed issue will contain a black and white / greyscale version). Please ensure at proofstage that the figure legends
of any colour figures refer the reader to the colour version of the figure which will be made available online only.
Tables
Number tables consecutively in accordance with their appearance in the text. Place footnotes to tables
below the table body and indicate them with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and
ensure that the data presented in tables do not duplicate results described elsewhere in the article.
References
Citation in text
Please ensure that
every reference cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be
given in full. Unpublished results and personal communications are not recommended in the reference list, but may be mentioned in the
text. If these references are included in the reference list they should follow the standard reference style of the journal and should
include a substitution of the publication date with either "Unpublished results" or "Personal communication" Citation of a reference
as "in press" implies that the item has been accepted for publication.
Web references
As a minimum, the full URL should be given. Any further information, if known (DOI, author names, dates, reference to a source publication,
etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired,
or can be included in the reference list.
Reference Style
Text:
Indicate references by number(s) in square brackets in line with the text. The actual authors can be referred to, but the reference
number(s) must always be given.
Example: "..... as demonstrated [3,6]. Barnaby and Jones [8] obtained a different result ...."
List:
Number the references (numbers in square brackets) in the list in the order in which they appear in the text.
Examples:
Reference to a journal publication:
[1] J. van der Geer, J.A.J. Hanraads, R.A. Lupton, J. Sci. Commun. 163 (2000) 51-59.
Reference
to a book:
[2] W. Strunk Jr., E.B. White, The Elements of Style, third ed., Macmillan, New York, 1979.
Reference to a chapter
in an edited book:
[3] G.R. Mettam, L.B. Adams, in: B.S. Jones, R.Z. Smith (Eds.), Introduction to the Electronic Age, E-Publishing,
Inc. New York, 1994, pp. 281-304.
Responsibility for the accuracy of bibliographic citations lies entirely with the authors.
Supplementary material
Elsevier accepts electronic supplementary material to support and enhance your scientific
research. Supplementary files offer the author additional possibilities to publish supporting applications, movies, animation sequences,
high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the
electronic version of your article in Elsevier Web products, including ScienceDirect:
http://www.sciencedirect.com. In order
to ensure that your submitted material is directly usable, please ensure that data are provided in one of our recommended file formats.
Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each
file. Video files: please supply 'stills' with your files: you can choose any frame from the video or make a separate image. These will
be used instead of standard icons and will personalize the link to your supplementary information. For more detailed instructions please
visit our artwork instruction pages at
http://www.elsevier.com/artworkinstructions.
Submission checklist
It is hoped that this list will be useful during the final checking of an article prior to sending
it to the journal's Editor for review. Please consult this Guide for Authors for further details of any item.
Ensure that the
following items are present:
One Author designated as corresponding Author:
• E-mail address
• Full postal
address
• Telephone and fax numbers
All necessary files have been uploaded
• Keywords
• All figure captions
• All tables (including title, description, footnotes)
Further considerations
• Manuscript has been "spellchecked"
and "grammar-checked"
• References are in the correct format for this journal
• All references mentioned in the Reference
list are cited in the text, and vice versa
• Permission has been obtained for use of copyrighted material from other sources
(including the Web)
• Color figures are clearly marked as being intended for color reproduction on the Web (free of charge)
and in print or to be reproduced in color on the Web (free of charge) and in black-and-white in print
• If only color on the
Web is required, black and white versions of the figures are also supplied for printing purposes
For any further information please
visit our customer support site at
http://epsupport.elsevier.com.
Use of the Digital Object Identifier
The Digital Object Identifier (DOI)
may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to
a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium
for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. The
correct format for citing a DOI is shown as follows (example taken from a document in the journal
Physics Letters B):
doi:10.1016/j.physletb.2003.10.071
When you use the DOI to create URL hyperlinks to documents on the web, they are guaranteed never to change.
Proofs
One set of page proofs (as PDF files) will be sent by e-mail to the corresponding author (if we do
not have an e-mail address then paper proofs will be sent by post) or, a link will be provided in the e-mail so that authors can download
the files themselves. Elsevier now provides authors with PDF proofs which can be annotated; for this you will need to download Adobe
Reader version 7 (or higher) available free from
http://www.adobe.com/products/acrobat/readstep2.html. Instructions on how
to annotate PDF files will accompany the proofs (also given online). The exact system requirements are given at the Adobe site:
http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win.
If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and
return them to Elsevier in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then
mark the corrections and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan
the pages and e-mail, or by post. Please use this proof only for checking the typesetting, editing, completeness and correctness of the
text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission
from the Editor. We will do everything possible to get your article published quickly and accurately. Therefore, it is important to ensure
that all of your corrections are sent back to us in one communication: please check carefully before replying, as inclusion of any subsequent
corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of
your article if no response is received.
Offprints
The corresponding author,
at no cost, will be provided with a PDF file of the article via e-mail. The PDF file is a watermarked version of the published article
and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use. Additional paper
offprints can be ordered by the authors. An order form with prices will be sent to the corresponding author.
For inquiries relating to the submission of articles (including electronic submission
where available) please visit this journal's homepage. You can track accepted articles at
http://www.elsevier.com/trackarticle
and set up e-mail alerts to inform you of when an article's status has changed. Also accessible from here is information on copyright,
frequently asked questions and more. Contact details for questions arising after acceptance of an article, especially those relating
to proofs, will be provided by the publisher.
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