Cellular Signalling will endeavour to give authors as rapid a decision as possible concerning the acceptability of their manuscript. Final
decisions concerning acceptability will be made both on the novelty of the work, its scientific content and appropriateness to the remit
of the journal. Cellular Signalling will accept original, full-length research papers, but not short reports, written in a concise style
that describes key, novel findings. Manuscripts should be submitted on-line for transmission to the Editorial Office. Cellular Signalling
will also publish Topical Reviews of some 5000-8000 words. In general reviews will be solicited by the Editorial Board. However, intending
contributors of review articles should send a brief summary of their proposed Topical Review to the Editorial Office for comment on its
possible acceptability prior to submission.
Manuscripts should be submitted online via the homepage of this journal
http://ees.elsevier.com/cls)
for transmittal to the Editorial Office.
Submission checklist
It is hoped that this list will be useful during the
final checking of an article prior to sending it to the journal's Editor for review. Please consult this Guide for Authors for further
details of any item.
Ensure that the following items are present:
One Author designated as corresponding Author: •
E-mail address • Full postal address • Telephone and fax numbers • All necessary files have been uploaded
• Keywords • All figure captions • All tables (including title, description, footnotes)
Further considerations:
• Manuscript has been spellchecked • References are in the correct format for this journal • All references mentioned
in the Reference list are cited in the text, and vice versa • Permission has been obtained for use of copyrighted material from
other sources (including the Web) • Colour figures are clearly marked as being intended for colour reproduction on the Web (free
of charge) and in print or to be reproduced in colour on the Web (free of charge) and in black-and-white in print • If only
colour on the Web is required, black and white versions of the figures are also supplied for printing purposes
Language Editing:
International Science Editing and Asia Science Editing can provide English language and copyediting services to authors who want to publish
in scientific, technical and medical journals and need assistance before they submit their article or, before it is
accepted for publication. Authors can contact these services directly: International Science Editing (http://www.internationalscienceediting.com) and Asia Science Editing (http://www.asiascienceediting.com) or, for more information about language editing services,
please contact authorsupport@elsevier.com who will be happy to deal with any questions.
Submission of articles General
It is essential to give a fax number and e-mail address when submitting a manuscript. Articles must be written in
good English.
Submission of an article implies that the work described has not been published previously (except in the form of an
abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its
publication is approved by all Authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that,
if accepted, it will not be published elsewhere in the same form, in English or in any other language, without the written consent of
the Publisher.
Revisions
Should Authors be requested by the Editor to revise the text, the revised version should be submitted
within eight weeks. After this period, the article will be regarded as a new submission.
Electronic format requirements for accepted
articles
We accept most wordprocessing formats, but Word, WordPerfect or LaTeX is preferred. Please do not submit PDF files because
this will cause delays upon acceptance (a PDF file is created automatically by the server for review purposes anyway). Always keep a
backup copy of the electronic file for reference and safety. Save your files using the default extension of the program used.
Presentation
of manuscript General
Please write your text in good English (American or British usage is accepted, but not a mixture
of these). Italics are not to be used for expressions of Latin origin, for example, in vivo, et al., per se. Use decimal points (not
commas); use a space for thousands (10 000 and above).
Authors in Japan please note that, upon request, Elsevier Japan will provide
authors with a list of people who can check and improve the English of their paper (before submission). Please contact our Tokyo office:
Elsevier, 4F Higashi-Azabu, 1 Chome Bldg, 1-9-15 Higashi-Azabu, Minato-ku, Tokyo 106-0044, Japan; phone: (03)-5561-5032; fax: (03)-5561-5045;
e-mail: jp.info@elsevier.com.
Provide the following data on the title page (in the order given).
Title. Concise and informative.
Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.
Author names and affiliations.
Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the Authors' affiliation addresses
(where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the
Author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name,
and, if available, the e-mail address of each Author.
Corresponding Author. Clearly indicate who is willing to handle correspondence
at all stages of refereeing and publication, also post-publication. Ensure that telephone and fax numbers (with country and area code)
are provided in addition to the e-mail address and the complete postal address.
Present/permanent address. If an Author has moved
since the work described in the article was done, or was visiting at the time, a "Present address" (or "Permanent address") may be indicated
as a footnote to that Author's name. The address at which the Author actually did the work must be retained as the main, affiliation
address. Superscript Arabic numerals are used for such footnotes.
Abstract. A concise and factual abstract is required. The abstract
should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separate
from the article, so it must be able to stand alone.
Keywords. Immediately after the abstract, provide a maximum of eight keywords,
avoiding general and plural terms and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations: only abbreviations
firmly established in the field may be eligible. These keywords will be used for indexing purposes.
Arrangement of the article
Introduction. State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary
of the results.
Experimental/Materials and methods. Provide sufficient detail to allow the work to be reproduced. Methods already
published should be indicated by a reference: only relevant modifications should be described.
Results. Results should be clear and
concise.
Discussion. This should explore the significance of the results of the work, not repeat them.
Conclusions. A short Conclusions
section is to be presented and should be divided into specific points.
Acknowledgements. Place acknowledgements, including information
on grants received, before the references, in a separate section, and not as a footnote on the title page.
References. See separate
section, below.
References
Responsibility for the accuracy of bibliographic citations lies entirely with the Authors.
Citations in the text: Please ensure that every reference cited in the text is also present in the reference list (and vice versa).
Any references cited in the abstract must be given in full. Unpublished results and personal communications are not recommended in the
reference list, but may be mentioned in the text. If these references are included in the reference list they should follow the standard
reference style of the journal and should include a substitution of the publication date with either "Unpublished results" or "Personal
communication" Citation of a reference as "in press" implies that the item has been accepted for publication.
Citing and listing
of Web references. As a minimum, the full URL should be given. Any further information, if known (Author names, dates, reference to a
source publication, etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different
heading if desired, or can be included in the reference list.
Indicate references by number(s) in square brackets in line with the
text. The actual Authors can be referred to, but the reference number(s) must always be given.
Example: "..... as demonstrated [3,6].
Barnaby and Jones [8] obtained a different result ...."
Number the references (numbers in square brackets) in the list in the order
in which they appear in the text.
Examples
Reference to a journal publication:
[1] J. van der Geer, J.A.J. Hanraads,
R.A. Lupton, J. Sci. Commun. 163 (2000) 51-59.
Reference to a book:
[2] W. Strunk Jr., E.B. White, The Elements of Style, third
ed., Macmillan, New York, 1979.
Reference to a chapter in an edited book:
[3] G.R. Mettam, L.B. Adams, in: B.S. Jones, R.Z. Smith
(Eds.), Introduction to the Electronic Age, E-Publishing, Inc. New York, 1994, pp. 281-304.
DNA sequences and GenBank Accession
numbers
Many Elsevier journals cite "gene accession numbers" in their running text and footnotes. Gene accession numbers refer
to genes or DNA sequences about which further information can be found in the databases at the National Center for Biotechnical Information
(NCBI) at the National Library of Medicine. Elsevier Authors wishing to enable other scientists to use the accession numbers cited in
their papers via links to these sources, should type this information in the following manner:
For each and every accession
number cited in an article, Authors should type the accession number in bold, underlined text. Letters in the accession
number should always be capitalised. (See Example below). This combination of letters and format will enable Elsevier's typesetters to
recognise the relevant texts as accession numbers and add the required link to GenBank's sequences.
Example:
"GenBank accession
nos. AI631510, AI631511, AI632198, and BF223228), a B-cell tumor from a chronic
lymphatic leukemia (GenBank accession no. BE675048), and a T-cell lymphoma (GenBank accession no. AA361117)".
Authors are encouraged to check accession numbers used very carefully. An error in a letter or number can result in a dead link.
In the final version of the printed article, the accession number text will not appear bold or underlined. In the final
version of the electronic copy, the accession number text will be linked to the appropriate source in the NCBI databases
enabling readers to go directly to that source from the article.
Preparation of supplementary data
Elsevier now accepts
electronic supplementary material (e-components) to support and enhance your scientific research. Supplementary files offer the Author
additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images, background datasets,
sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier
Web products, including ScienceDirect: http://www.sciencedirect.com.
In order to ensure that your submitted material is directly usable, please ensure that data is provided in one of our recommended file
formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption
for each file. For more detailed instructions please visit our artwork instruction pages at http://www.elsevier.com/artworkinstructions.
Files can be stored on 3.5 inch diskette, ZIP-disk or CD (either MS-DOS or Macintosh). This journal offers electronic submission services
and supplementary data files can be uploaded via the home page of this journal via http://www.elsevier.com/journals.
Ethics of experimentation
Authors describing investigations in animals or on human tissue must specify that the research
conformed to the stipulations of the appropriate institutional review body and ethics committee.
Preparation of illustrations General points• Make sure you use uniform lettering and sizing of your original artwork • Save text in illustrations
as "graphics" or enclose the font. • Only use the following fonts in your illustrations: Arial, Courier, Helvetica, Times,
Symbol. • Number the illustrations according to their sequence in the text. • Use a logical naming convention for your
artwork files. • Provide all illustrations as separate files and as hardcopy printouts on separate sheets. • Provide
captions to illustrations separately. • Produce images near to the desired size of the printed version.
Your are urged to
visit this site; some excerpts from the detailed information are given here.Formats
Regardless of the application
used, when your electronic artwork is finalised, please "save as" or convert the images to one of the following formats (Note the resolution
requirements for line drawings, halftones, and line/halftone combinations given below.):
EPS: Vector drawings. Embed the font or
save the text at "graphics".
TIFF: Colour or greyscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line
drawings: use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (colour or greyscale): a minimum of 500 dpi is required.
DOC, XLS or PPT: If your electronic artwork is created in any of these Microsoft Office Applications please supply "as is".
Please
do not: • Supply embedded graphics in your wordprocessor (spreadsheet, presentation) document; • Supply files that
are optimised for screen use (like GIF, BMP, PICT, WPG); the resolution is too low; • Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.
Colour illustrations
Submit colour illustrations
as original photographs, high-quality computer prints or transparencies, close to the size expected in publication, or as 35 mm slides.
Please make sure that artwork files are in an acceptable format (TIFF, EPS or MS Office files) and with the correct resolution. Polaroid
colour prints are not suitable. If, together with your accepted article, you submit usable colour figures then Elsevier will ensure,
at no additional charge, that these figures will appear in colour on the Web (e.g., ScienceDirect and other sites) regardless of whether
or not these illustrations are reproduced in colour in the printed version. For colour reproduction in print, you will receive information
regarding the costs from Elsevier after receipt of your accepted article. Please indicate your preference for colour in print or on the
Web only. For further information on the preparation of electronic artwork, please see http://www.elsevier.com/artworkinstructions.
Please note: Because of technical complications which can arise by converting colour figures to "grey scale" (for the printed version
should you not opt for colour in print) please submit in addition usable black and white versions of all the colour illustrations.
Proofs
When your manuscript is received by the Publisher it is considered to be in its final form. Proofs are not to be regarded
as "drafts".
One set of page proofs in PDF format will be sent by e-mail to the corresponding Author, to be checked for typesetting/editing.
No changes in, or additions to, the accepted (and subsequently edited) manuscript will be allowed at this stage. Proofreading is solely
your responsibility.
A form with queries from the copyeditor may accompany your proofs. Please answer all queries and make any corrections
or additions required.
The Publisher reserves the right to proceed with publication if corrections are not communicated. Return corrections
within seven days of receipt of the proofs. Should there be no corrections, please confirm this.
Elsevier will do everything possible
to get your article corrected and published as quickly and accurately as possible. In order to do this we need your help. When you receive
the (PDF) proof of your article for correction, it is important to ensure that all of your corrections are sent back to us in one communication.
Subsequent corrections will not be possible, so please ensure your first sending is complete. Note that this does not mean you have any
less time to make your corrections, just that only one set of corrections will be accepted.
Offprints
The corresponding
author, at no cost, will be provided with a PDF file of the article via e-mail or, alternatively, 25 free paper offprints. The PDF file
is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining
the terms and conditions of use.
The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail.
The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer
outlining the terms and conditions of use.
US National Institutes of Health (NIH) voluntary posting ("Public Access") policy.
Elsevier facilitates author response to the NIH voluntary posting request (referred to as the NIH "Public Access Policy"; see http://www.nih.gov/about/publicaccess/index.htm
) by posting the author's peer-reviewed manuscript directly to PubMed Central on request from the author, 12 months after formal publication.
Upon notification from Elsevier of acceptance, we will ask you to confirm via e-mail (by e-mailing us at NIHauthorrequest@elsevier.com
that your work has received NIH funding and that you intend to respond to the NIH policy request, along with your NIH award number to
facilitate processing. Upon such confirmation, Elsevier will submit to PubMed Central on your behalf a version of your manuscript that
will include peer-review comments, for posting 12 months after formal publication. This will ensure that you will have responded fully
to the NIH request policy. There will be no need for you to post your manuscript directly with PubMed Central, and any such posting is
prohibited.
Authors' rights:
As an author you (or your employer or institution) may do the following: • make copies
(print or electronic) of the article for your own personal use, including for your own classroom teaching use • make copies
and distribute such copies (including through e-mail) of the article to research colleagues, for the personal use by such colleagues
(but not commercially or systematically, e.g., via an e-mail list or list server) • post a pre-print version of the article
on Internet websites including electronic pre-print servers, and to retain indefinitely such version on such servers of sites •
post a revised personal version of the final text of the article (to reflect changes made in the peer review and editing process) on
your personal or institutional website or server, with a link to the journal homepage (on Elsevier.com) • present the article
at a meeting or conference and to distribute copies of the article to the delegates attending such a meeting • for your employer,
if the articles is a 'work for hire', made within the scope of your employment, your employer may use all or part of the information
in the article for other intra-company use (e.g., training) • retain patent and trademark rights and rights to any processes
or procedure described in the article • include the article in full or in part in a thesis or dissertation (provided that this
is not to be published commercially) • use the article or any part thereof in a printed compilation of your works, such as collected
writings or lecture notes (subsequent to publication of your article in the journal) • prepare other derivative works, to extend
the article into book-length form, or to otherwise re-use portions or excerpts in other works, with full acknowledgement of its original
publication in the journal.
