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VIRUS RESEARCH
An International Journal of Molecular and Cellular Virology

Guide for Authors

On-Line submission to the journal prior to acceptance
Submission to this journal proceeds totally online. Use the following guidelines to prepare your article. Via the homepage of this journal (External link http://www.elsevier.com/journals) you will be guided stepwise through the creation and uploading of the various files. The system automatically converts source files to a single Adobe Acrobat PDF version of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail and via the author's homepage, removing the need for a hard-copy paper trail.


The above represents a very brief outline of this form of submission. It can be advantageous to print this "Guide for Authors" section from the site for reference in the subsequent stages of article preparation.


General
It is essential to give a fax number and an e-mail address when submitting a manuscript. Articles must be written in good English.


Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without the written consent of the copyright holder.


Upon acceptance of an article, authors will be asked to sign a 'Journal Publishing Agreement' (for more information on this and copyright see External link http://www.elsevier.com/copyright). Acceptance of the agreement will ensure the widest possible dissemination of information. An e-mail (or letter) will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement. Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations (please consult External link http://www.elsevier.com/permissions).
If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: please consult External link http://www.elsevier.com/permissions.
All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See also External link http://www.elsevier.com/conflictsofinterest.


Funding body agreements and policies
Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions of their grant awards. To lean more about existing agreements and policies please visit External link http://www.elsevier.com/fundingbodies.


Authors' rights
As an author you (or your employer or institution) retain certain rights; for details you are referred to External link http://www.elsevier.com/authorstrights.


Types of Articles


Research articles should generally be divided into Summary, Introduction, Materials and Methods, Results, Discussion and Acknowledgements and References.


Short communications, approximately 8 typewritten pages in total, including a summary, illustrations and keywords but written without section headings.


Review articles on topics of current interest in Virology will be published. While some authors will be invited to write reviews, others wishing to contribute a review article are invited to contact Dr. B.W.J. Mahy at virology@bellsouth.net.


Book Reviews or Meeting Reports


Electronic format requirements for accepted articles


Wordprocessor documents
It is important that the files be saved in the native It is important that the file be saved in the native format of the wordprocessor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the wordprocessor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. Do not embed "graphically designed" equations or tables, but prepare these using the wordprocessor's facility. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: External link http://www.elsevier.com/authors). Do not import the figures into the text file but, instead, indicate their approximate locations directly in the electronic text and on the manuscript. See also the section on Preparation of electronic illustrations. To avoid unnecessary errors you are strongly advised to use the "spellchecker" function of your wordprocessor.
Characters not available on your wordprocessor should not be left open but indicated by a unique code (e.g., alpha, @, #, etc. for the Greek letter α). Such codes should be used consistently throughout the entire text. Please make a list of such codes and provide a key. Do not allow your word processor to introduce word splits.


Presentation of manuscripts
Please write your text in good English (American or British usage is accepted, but not a mixture of these). Italics are not to be used for expressions of Latin origin, for example, in vivo, et al., per se. Use decimal points (not commas); use a space for thousands (10 000 and above).


Language Editing
Authors who require information about language editing and copyediting services pre- and post-submission please visit External link http://www.elsevier.com/languagepolishing or contact authorsupport@elsevier.com for more information. Please note Elsevier neither endorses nor takes responsibility for any products, goods or services offered by outside vendors through our services or in any advertising. For more information please refer to our Terms & Conditions External link http://www.elsevier.com/termsandconditions.


Please provide the following data on the title page (in the order given):


Title
Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.


Author names and affiliations
Where the family name may be ambiguous (e.g. a double name), please indicate this clearly. Present the Authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the Author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name, and, if available, the e-mail address of each Author.


Corresponding Author
Clearly indicate who is willing to handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that telephone and fax numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address.


Present/permanent address
If an Author has moved since the work described in the article was done, or was visiting at the time, a "Present address" (or "Permanent address") may be indicated as a footnote to the Author's name. The address at which the Author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.


Abstract
A concise and factual abstract is required (maximum length 200 words). The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separate from the article, so it must be able to stand alone. References should therefore be avoided, but if essential, they must be cited in full, without reference to the reference list.


Keywords
Immediately after the abstract, provide a maximum of 6 keywords, avoiding general and plural terms and multiple concepts (avoid, for example, "and", "of"). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes.


Abbreviations
Define abbreviations that are not standard in this field at their first occurrence in the article: in the abstract but also in the main text after it. Ensure consistency of abbreviations throughout the article.


Arrangement of the article


Subdivision of the article
Divide your article into clearly defined and numbered sections. Subsections should be numbered 1.1 (then 1.1.1, 1.1.2,), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for internal cross-referencing: do not just refer to "the text". Any subsection may be given a brief heading. Each heading should appear on its own separate line.


Introduction
State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.


Experimental/Materials and methods
Provide sufficient detail to allow the work to be reproduced.


Results
Results should be clear and concise.


Discussion
This should explore the significance of the results of the work, not repeat them.


Conclusions
The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section.


Acknowledgements
Place acknowledgements, including information on grants received, before the references, in a separate section, and not as a footnote on the title page.


References
See separate section, below.


Figure captions, tables, figures, schemes
Present these, in this order, at the end of the article. They are described in more detail below. High-resolution graphics files must always be provided separate from the main text file (see Preparation of illustrations).


Footnotes
Footnotes should be used sparingly. Number them consecutively throughout the article, using superscript Arabic numbers. Do not include footnotes in the Reference list.


Tables
Number tables consecutively with Arabic numerals in accordance with their appearance in the text. Place footnotes to tables below the table body and indicate them with superscript lowercase letters. Avoid vertical rules. All tables must have descriptive headings and possible legends below; both headings and legends should be understandable without reference to the text. Be sparing in the use of tables and ensure that the data presented in tables do not duplicate results described elsewhere in the article.


Nomenclature and units
Follow internationally accepted rules and conventions: use the international system of units (SI). If other quantities are mentioned, give their equivalent in SI.


Virus nomenclature


Each virus should be identified at least once, preferably in the 'Introduction' or 'Materials and Methods' section, using formal family, genus, and species terms and where possible by using a precise strain designation term as developed by an internationally recognized specialty group or culture collection. Please note that the word type is not used before species designations that include a number. Formal terms used for virus families, genera, and species should be those approved by the International Committee on Taxonomy of Viruses (ICTV):Fauquet, C.M., Mayo, M.A.,Maniloff, J., Desselberger, U., and Ball, L.A.(2005) Virus Taxonomy, Classification and Nomenclature of Viruses. Eighth ICTV Report, Academic Press, an imprint of Elsevier. This volume also includes standard abbreviations for species. Once formal taxonomic names have been given in a paper, vernacular terms may be used.


Formal taxonomic nomenclature
In formal taxonomic usage, the first letters of virus order, family, subfamily, genus and species names are capitalized and the terms are printed in italics. Other words in the species names are not capitalized unless they are proper nouns or parts of nouns, for example West Nile virus. In formal usage, the name of the taxon should precede the term for the taxonomic unit; for example; "the family Paramyxoviridae," "the genus Morbillivirus." The following represent examples of full formal taxonomic terminology:

1. Order Mononegavirales, family Rhabdoviridae, genus Lyssavirus, species Rabies virus.


2. Family Poxviridae, subfamily Chordopoxvirinae, genus Orthopoxvirus, species Vaccinia virus.


3. Family Picornaviridae, genus Enterovirus, species Poliovirus.


4. Family Bunyaviridae, genus Tospovirus, species Tomato spotted wilt virus.


Vernacular Taxonomic Nomenclature
In formal vernacular usage, virus order, family, subfamily, genus and species names are written in lower case Roman script: they are not capitalized, nor are they printed in italics or underlined. In informal usage, the name of the taxon should not include the formal suffix, and the name of the taxon should follow the term for the taxonomic unit; for example "the picornavirus family, the enterovirus genus." One particular source of ambiguity in vernacular nomenclature lies in the common use of the same root terms in formal family, genus or species names. Imprecision stems from not being able to easily identify in vernacular usage which hierarchical level is being cited. For example, the vernacular name "paramyxovirus" might refer to the family Paramyxoviridae, or one species in the genus Respirovirus, such as Human parainfluenza virus 1. The solution in vernacular usage is to avoid "jumping" hierarchical levels and to add taxon identification wherever needed. For example, when citing the taxonomic placement of Human parainfluenza virus 1, taxon identification should always be added: Human Parainfluenza virus 1 is a species in the genus Respirovirus, family Paramyxoviridae. In this example, as is usually the case, adding the information that this virus is also a member of the subfamily Paramyxovirinaeand the order Mononegavirales is unnecessary.


It should be stressed that italics and capital initial letters need be used only if the species name refers to the taxonomic category. When the name refers to viral objects such as virions present in a preparation or seen in an electron micrograph, italics and capital initial letters are not needed and the names are written in lower case Roman script. This also applies when the names are used in adjectival form, for instance tobacco mosaic virus polymerase. The use of italics when referring to the name of a species as a taxonomic entity signals that it has the status of an officially recognized species. The 8th ICTV Report (Fauquet, C.M. et al., 2005, Academic Press, an imprint of Elsevier) should be consulted to ascertain which names have been approved as official species names. When the taxonomic status of a new putative species is uncertain or its position within an established genus has not been clarified, it is considered a tentative species and its name is not written in italics although its initial letter is capitalized.


Origins of bioreagents - The origins of bioreagents should be described adequately, including citation of culture collections, companies, or colleagues from whom the bioreagents were obtained. If viruses were collected from nature, the collecting site and procedure should also be properly described. Bioreagents include but are not necessarily limited to virus strains and species, antibodies, and cell lines.


GenBank/DNA sequence linking


Many Elsevier journals cite "gene accession numbers" in their running text and footnotes. Gene accession numbers refer to genes or DNA sequences about which further information can be found in the databases at the National Center for Biotechnical Information (NCBI) at the National Library of Medicine. Elsevier Authors wishing to enable other scientists to use the accession numbers cited in their papers via links to these sources, should type this information in the following manner:
For each and every accession number cited in an article, Authors should type the accession number in bold, underlined text. Letters in the accession number should always be capitalised. (See Example below). This combination of letters and format will enable Elsevier's typesetters to recognise the relevant texts as accession numbers and add the required link to GenBank's sequences.
Example: "GenBank accession nos. AI631510 , AI631511 , AI632198 , and BF223228) , a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048 ), and a T-cell lymphoma (GenBank accession no. AA361117 )".
Authors are encouraged to check accession numbers used very carefully. An error in a letter or number can result in a dead link. In the final version of the printed article, the accession number text will not appear bold or underlined. In the final version of the electronic copy, the accession number text will be linked to the appropriate source in the NCBI databases enabling readers to go directly to that source from the article.


Preparation of supplementary data.
Elsevier now accepts electronic supplementary material (e-components) to support and enhance your scientific research. Supplementary files offer the Author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect: External link http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please ensure that data is provided in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file.


Citations in the text:
Please ensure that every reference cited in the text is also present in the reference list (and vice versa). Any references cited in the abstract must be given in full. Citation of a reference as "in press" implies that the item has been accepted for publication and a copy of the title page of the relevant article must be submitted.


Citing and listing of Web references
As a minimum, the full URL should be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired, or can be included in the reference list.


Text:
All citations in the text should refer to:
1. Single Author: the Author's name (without initials, unless there is ambiguity) and the year of publication;
2. Two Authors: both Authors' names and the year of publication;
3. Three or more Authors: first Author's name followed by "et al." and the year of publication.
Citations may be made directly (or parenthetically). Groups of references should be listed first alphabetically, then chronologically.
Examples: "as demonstrated (Allan, 1996a, 1996b, 1999; Allan and Jones, 1995). Kramer et al. (2000) have recently shown ...."
List: References should be arranged first alphabetically and then further sorted chronologically if necessary. More than one reference from the same Author(s) in the same year must be identified by the letters "a", "b", "c", etc., placed after the year of publication.
Examples:
Reference to a journal publication:
Van der Geer, J., Hanraads, J.A.J., Lupton, R.A., 2000. The art of writing a scientific article. J. Sci. Commun. 163, 51-59.
Reference to a book:
Strunk Jr., W., White, E.B., 1979. The Elements of Style, third ed. Macmillan, New York.
Reference to a chapter in an edited book:
Mettam, G.R., Adams, L.B., 1999. How to prepare an electronic version of your article, in: Jones, B.S., Smith, R.Z. (Eds.), Introduction to the Electronic Age. E-Publishing Inc., New York, pp. 281-304.


Journal names should be abbreviated according to:
List of serial title word abbreviations External link http://www.issn.org/lstwa.html


Use of the Digital Object Identifier (DOI)
The digital object identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. The correct format for citing a DOI is shown as follows (example taken from a document in the journal Physics Letters B):
doi:10.1016/j.physletb.2003.10.071
When you use the DOI to create URL hyperlinks to documents on the web, they are guaranteed never to change.


Electronic Artwork
A detailed guide on electronic artwork is available on our website: External link http://www.elsevier.com/artworkinstructions.


Colour Illustrations
Please make sure that artwork files are in an accepted format (TIFF, EPS, or MS Office files) and with the correct resolution). If, together with your accepted article, you submit usable colour figures then Elsevier will ensure, at no additional charge, that these figures will appear in colour on the Web (e.g., ScienceDirect and other sites) in addition to colour reproduction in print.


Author Proofs
When your manuscript is received by the Publisher it is considered to be in its final form. Proofs are not to be regarded as "drafts". One set of page proofs in PDF format will be sent by e-mail to the corresponding Author, to be checked for typesetting/editing. No changes in, or additions to, the accepted (and subsequently edited) manuscript will be allowed at this stage. Proofreading is solely your responsibility. The Publisher reserves the right to proceed with publication if corrections are not communicated. Return corrections within 2 days of receipt of the proofs. Should there be no corrections, please confirm this.


Elsevier will do everything possible to get your article corrected and published as quickly and accurately as possible. IN order to do this we need your help. When you receive the (PDF) proof of your article for correction, it is important to ensure that all of your corrections are sent back to us in one communication. Subsequent corrections will not be possible, so please ensure your first sending is complete. Note that this does not mean you have any less time to make your corrections, just that only one set of corrections will be accepted.


Offprints
The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail or, alternatively, 25 free paper offprints. The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use. Additional paper offprints can be ordered by the authors. An order form with prices will be sent to the corresponding author.


Captions
Ensure that each illustration has a caption. Supply captions separately, not attached to the figure. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.

Line drawings
The lettering and symbols, as well as other details, should have proportionate dimensions, so as not to become illegible or unclear after possible reduction; in general, the figures should be designed for a reduction factor of two to three. The degree of reduction will be determined by the Publisher. Illustrations will not be enlarged. Consider the page format of the journal when designing the illustrations.
Do not use any type of shading on computer-generated illustrations.

Photographs (halftones)
Remove non-essential areas of a photograph. Do not mount photographs unless they form part of a composite figure. Where necessary, insert a scale bar in the illustration (not below it), as opposed to giving a magnification factor in the caption.
Note that photocopies of photographs are not acceptable.

Colour Illustrations
Please make sure that artwork files are in an acceptable format (TIFF, EPS, or MS Office files) and with the correct resolution). If, together with your accepted article, you submit usable colour figures then Elsevier will ensure, at no additional charge, that these figures will appear in colour on the Web (e.g., ScienceDirect and other sites) in addition to colour reproduction in print. For further information on the preparation of electronic artwork, please see External link http://www.elsevier.com/artworkinstructions. When your manuscript is received by the Publisher it is considered to be in its final form. Proofs are not to be regarded as "drafts".

One set of page proofs in PDF format will be sent by e-mail to the corresponding Author, to be checked for typesetting/editing. No changes in, or additions to, the accepted (and subsequently edited) manuscript will be allowed at this stage. Proofreading is solely your responsibility.

A form with queries from the copyeditor may accompany your proofs. Please answer all queries and make any corrections or additions required.

The Publisher reserves the right to proceed with publication if corrections are not communicated.
Return corrections within 2 days of receipt of the proofs. Should there be no corrections, please confirm this.

Elsevier will do everything possible to get your article corrected and published as quickly and accurately as possible. In order to do this we need your help. When you receive the (PDF) proof of your article for correction, it is important to ensure that all of your corrections are sent back to us in one communication. Subsequent corrections will not be possible, so please ensure your first sending is complete. Note that this does not mean you have any less time to make your corrections, just that only one set of corrections will be accepted.

Offprints
Twenty-five (25) offprints will be provided free of charge. Additional reprints may be purchased at the proof stage.
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