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REGULATORY PEPTIDES

Guide for Authors

Submission of a paper to Regulatory Peptides is understood to imply that it has not previously been published (except in an abstract form), and that it is not being considered for publication elsewhere. Manuscripts submitted under multiple authorship are reviewed on the assumption that all listed authors concur with the submission and that a copy of the final manuscript has been approved by all authors and tacitly or explicity by the responsible authorities in the laboratories where the work was carried out. If accepted, the manuscript shall not be published elsewhere in the same form, in either the same or another language, without the consent of the Editors and Publisher.

Electronic submission of manuscripts is strongly recommended. Authors should consult External link http://www.elsevier.com for details

Regulatory Peptides Editorial Office
Prof. W.E. Schmidt
Dept. of Medicine I, Ruhr-University Bochum, St. Josef Hospital, Gudrunstr. 56, D-44791 Bochum, Germany.
Phone: (+49)234-509-2311, Fax: (+49)234-509-2309, Email: Wolfgang.E.Schmidt@ruhr-uni-bochum.de

Online Submission: Submission to this journal is online. Use the following guidelines to prepare your article. Via the EES page of this journal (External link http://ees.elsevier.com/regpep/) you will be guided stepwise through the creation and uploading of the various files. The system automatically converts source files to a single Adobe Acrobat PDF version of the article, which is used in the peer-review process. Although manuscript source files are converted to a PDF at the time of submission (for the review process) the source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail and via the Journal's web site.
There are no submission fees, page charges, or obligatory reprint orders (see Reprints).

Regulatory Peptides publishes high quality, novel, original papers on laboratory and clinical experimental studies. Reviews of current areas of research are generally by invitation but suggestions are most welcome. Comments on reports and reviews will be considered for publication in Letters. Only manuscripts which deal with original research not previously published and not under consideration for publication in other journals will be considered. All papers submitted for review will be subjected to an editorial decision to accept, revise or reject within one month. It is expected that all issues will be published within two months of receipt of the last paper of that issue. All manuscripts will be considered on an equivalent basis of scientific rigour and peer evaluation. In no case should articles exceed 12 printed pages. Important new and exciting data can be published as a Rapid communication. These will only be accepted if minor or no revisions are requested and will undergo an accelerated publishing procedure. Manuscripts should be submitted to either Editor-in-Chief at the addresses at the inside of the front cover.
Manuscripts, written in English, must be submitted in double-spaced typing on pages of uniform size. For papers 21.5 x 28 cm, with 4-cm margins, the following estimations provide a guide to final article length: 2 typewritten pages or 3 `average' figures with legends or 25 references =1 printed page. S.I. units should be used throughout. Papers which will be longer than 5 printed pages should be divided into the following sections, headed by captions (Introduction; Materials and Methods; Results; Discussion; Acknowledgements). The first page of each paper should contain the title and a single-spaced abstract of 200 words or less which describes the experimental objectives, results and conclusions.The title of the paper should be brief; no longer than 100 characters in length, and should capture and communicate the key message of your research to a broader audience. To aid this, abbreviations, unless familiar to a broad audience, should be avoided. Authors should provide a list of not more than 6 key words, not included in the title of the manuscript, for subsequent indexing.

Electronic manuscripts. Electronic manuscripts have the advantage that there is no need for the rekeying of text, thereby avoiding the possibility of introducing errors and resulting in reliable and fast delivery of proofs. Please do not split the article into separate files (title pages as one file, text as another, etc.). Ensure that the letter `l' and digit `1' (also letter `O' and digit `0') have been used properly, and structure your article (tabs, indents, etc.) consistently. Characters not available on your wordprocessor (Greek letters, mathematical symbols, etc.) should not be left open but indicated by a unique code (e.g., gralpha, @, #, etc., for the Greek letter α). Such codes should be used consistently throughout the entire text. Please make a list of such codes and provide a key. Do not allow your wordprocessor to introduce word splits and do not use a `justified' layout. Please adhere strictly to the general instructions on style/arrangement and, in particular, the reference style of the journal. It is very important that you save your file in the wordprocessor format. If your wordprocessor features the option to save file `in flat ASCII', please do not use it. Format your disk correctly and ensure that only the relevant file (one complete article only) is on the disk. Also, specify the type of computer and wordprocessing package used and label the disk with your name and the name of the file on the disk. After final acceptance, your disk plus one, final, printed and exactly matching version (as a printout) should be submitted together to the accepting editor. It is important that the file on disk and the printout are identical. Both will then be forwarded by the editor to Elsevier. Further information may be obtained from the Publisher.
Author's full names, academic or professional affiliations, and complete postal addresses of each author should be included, on a separate title page. The name and address of the author to whom correspondence may be sent should be indicated, including telephone and fax number for immediate enquiry.

Literature references. Citation of literature references in the text should be given at the appropriate places as numbers in square brackets. All references cited in the text should be listed at the end of the paper on a separate page (also double-spaced), arranged in numerical order of citation in the text, not in alphabetical order. Literature references must be complete, including initials of the authors cited, title of paper referred to, abbreviated title, volume, year, and first and last page numbers of the article in a periodical. The abbreviations of journal titles should conform to those used in the `List of Serial Title Word Abbreviations', International Serials Data System, Paris France (ISBN 2-904938-02-8). (See example 1 below). The form of literature references. to books should be: author(s), initials, title of book, publisher and city, year and page number referred to. (See example 2 below.)

Language Polishing:

Authors who require information about language editing and copyediting services pre- and post-submission, please visit External link http://www.elsevier.com/locate/languagepolishing or contact authorsupport@elsevier.com for more information. Please note Elsevier neither endorses nor take responsbility for any products, good or services offered by outside vendors through our services or in any advertising. For more information please refer to our Terms and Conditions External link http://www.elsevier.com/termsconditions.

Ethics:

When human subjects are used, manuscripts must be accompanied by a statement that the experiments were undertaken with the understanding and written consent of each subject, with the approval of the appropriate local ethics committee, and in compliance with national legislation and the Code of Ethical Principles for Medical Research Involving Human Subjects of the World Medical Association (Declaration of Helsinki) [External link http://www.wma.net/e/policy/b3.htm]. When experimental animals are used, the materials and methods section must clearly indicate that adequate measures were taken to minimise pain or discomfort, and that the experiments were conducted in accordance with international standards on animal welfare as well as being compliant with local and national regulations. Studies are expected to be compliant with minimal standards as defined by the European Communities Council Directive of 24 November 1986 (86/609/EEC).

Copyright:

Upon acceptance of an article, authors will be asked to Transfer copyright. This transfer will ensure the widest possible dissemination of information. If material from other copyrighted works is included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has pre-printed forms for use by authors in these cases: contact Elsevier Rights Department, P.O. Box 800, Oxford, OX5 1DX, UK, phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: permissions@elsevier.com. Requests may also be completed online via the Elsevier home page (External link http://www.elsevier.com/locate/permissions).

References to authors contributing to multi-author books or to proceedings printed in book form should be similar to those for books. (See example 3 below.)

Examples:
[1] Lovrecich M, Rubessa F. Effect of loading parameters on theophylline release from polystyrene beads. Int. J. Phar. 1987;40:63-72.
[2] Deming SN, Morgan SL. Experimental design: a chemometric approach. Amsterdam: Elsevier, 1987.
[3] Mendell LM, Munson JB, Collins III WF. Changes in peripheral and central axonal projections of sensory fibers following muscle nerve transection. In: Seil FJ, Herbert E, Carlson BM, editors. Neural regeneration, progress in brain research. Amsterdam: Elsevier, 1987:231-38.

Numbered references to personal communications and unpublished data should not be included. If essential, such material may be incorporated at the appropriate place in the text.

Figures:

Figures must be self-explanatory, titled, cited in order in the text, and numbered consecutively with Arabic numerals. On separate pages, type figure titles with their (brief) legends. Figures should not be embedded in text. Several figures may be grouped into a plate on one page. Lettering on micrographs should be clearly legible. Letters 2 mm high are recommended. Limit the field of micrographs to structures specifically discussed in the report. Symbols and areas of special interest should not be close to the edges. Give figure magnification in the legends and on the figures (micrometer scale). Symbols (minimum 3 mm height) used on micrographs must be explained in the figure legends. For detailed artwork instructions, see External link http://www.elsevier.com/artworkinstructions.

Colour Figures:

If together with your accepted article, you submit usable colour figures, then Elsevier will ensure, at no additional charge, that these figures will appear in colour on the Web (e.g., ScienceDirect and other sites) regardless of whether these illustrations are reproduced in colour in the printed version. For colour reproduction in print, you will receive information regarding the costs from Elsevier after receipt of your accepted article. For further information on the preparation of electronic artwork, please see External link http://www.elsevier.com/artworkinstructions [Please note: Because of technical complications that can arise in converting colour figures to "grey scale" (for the printed version should you not opt for colour in print), please submit in addition usable black-and-white files corresponding to all the colour illustrations.

Tables. Tables of numerical data should be typed (double-spaced), each on a separate page, numbered in sequence in numbers (Table 1, 2, etc.), provided with a concise heading, and referred to in the text as Table 1, Table 2, etc.

Instructions regarding GenBank/DNA Sequence Linking:


DNA sequences and GenBank Accesion numbers: Many Elsevier journals cite "gene accession numbers" in their running text and footnotes. Gene accession numbers refer to genes or DNA sequences about which further information can be found in the database at the National Center for Biotechnical Information (NCBI) at the National Library of Medicine. Elsevier authors wishing to enable other scientists to use the accession numbers cited in their papers via links to these sources, should type this information in the following manner:
For each and every accession number cited in an article, authors should type the accession number in bold, underlined text. Letters in the accession number should always be capitalised. (See Example 1 below). This combination of letters and format will enable Elsevier's typesetters to recognize the relevant texts as accession numbers and add the required link to GenBank's sequences.


Example 1: "GenBank accession nos. AI631510, AI631511, AI632198, and BF223228 ), a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048 ), and a T-cell lymphoma (GenBank accession no. AA361117 )".


Authors are encouraged to check accession numbers used very carefully. An error in a letter or number can result in a dead link.
In the final version of the printed article, the accession number text will not appear bold or underlined (see Example 2 below).


Example 2: "GenBank accession nos. AI631510, AI631511, AI632198, and BF223228, a B-cell tumor from a chronic lymphatic leukemia (GenBank accession no. BE675048), and a T-cell lymphoma (GenBank accession no. AA361117)".


In the final version of the electronic copy, the accession number text will be linked to the appropriate source in the NCBI databases enabling readers to go directly to that source from the article.


Supplementary material:

Electronic supplementary material is now accepted to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting applications, movies, animation sequences, high-resolution images, background datasets, sound clips and more. Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier web products, including ScienceDirect: External link http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please ensure that data is provided in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply a concise and descriptive caption for each file. For more detailed instructions please visit our Corporate Website at External link http://www.elsevier.com/authors.

US National Institutes of Health (NIH) voluntary posting (" Public Access") policy

Elsevier facilitates author response to the NIH voluntary posting request (referred to as the NIH "Public Access Policy"; see External link http://www.nih.gov/about/publicaccess/index.htm) by posting the peer-reviewed author's manuscript directly to PubMed Central on request from the author, 12 months after formal publication. Upon notification from Elsevier of acceptance, we will ask you to confirm via e-mail (by e-mailing us at NIHauthorrequest@elsevier.com) that your work has received NIH funding and that you intend to respond to the NIH policy request, along with your NIH award number to facilitate processing. Upon such confirmation, Elsevier will submit to PubMed Central on your behalf a version of your manuscript that will include peer-review comments, for posting 12 months after formal publication. This will ensure that you will have responded fully to the NIH request policy. There will be no need for you to post your manuscript directly with PubMed Central, and any such posting is prohibited.

PDF proofs will be sent by e-mail to the corresponding author. To avoid delay in publication, only necessary changes should be made, and corrections should be returned promptly.

Offprints: The corresponding author, at no cost, will be provided with a pdf offprint. Should they wish, they can choose to receive 25 free offprints instead.

Author enquiries:

For enquiries relating to the submission of articles (including electronic submission where available) please visit this journal's EES page. You can track accepted articles at External link http://www.elsevier.com/trackarticle and set up e-mail alerts to inform you of when an article's status has changed, as well as copyright information, frequently asked questions and more. Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided after registration of an article for publication.

Disclaimer:

Whilst every effort is made by the publishers and editorial board to see that no inaccurate or misleading data, opinion or statement appears in this journal, they wish to make it clear that the data and opinions appearing in the articles and advertisements herein are the sole responsibility of the contributor or advertiser concerned. Accordingly, the publishers, the editorial board and editors and their respective employees, officers and agents accept no responsibility or liability whatsoever for the consequences of any inaccurate or misleading data, opinion or statement.
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