Guide for Authors
Journal
of Pharmacological and Toxicological Methods publishes articles on methods of investigation used in pharmacology, safety pharmacology
and toxicology. Defined in the broadest sense. With its international editorial board and noted contributors,
Journal of Pharmacological
and Toxicological Methods is the leading journal devoted exclusively to the elaboration and validation of experimental methods.
For more details on how to write a world class paper, please visit our
Pharmacology
Author Resources page.
Authors are encouraged to submit supplementary video material to enrich their written article.
Authors are encouraged to submit video material or animation sequences to support and enhance your scientific research. For
more information please see the paragraph on video data below.
Types of paper
The
Journal
of Pharmacological and Toxicological Methods publishes papers in a range of categories:
- "Original articles": description
and characterization of a new or modified disease model, method, technique, apparatus or approach to analysis of data. This may include
interspecies comparisons that contrast drug actions from a model relevance perspective;
- "Brief communications" detailing simple
modifications of an existing model, method, technique, apparatus or approach to analysis of data;
- "How To" articles that provide
step-by-step guidance on the execution of a specific technique;
- "Appraisal of state-of-the-art" or "Historical review" of particular
models, methods, techniques or apparatus;
- "Methods in drug discovery" - perhaps the most important category. Here, by showing
how a method was used to select a drug that was eventually found to be clinically effective, the author establishes validation of the
method.
Ethics in publishing
For
information on Ethics in publishing and Ethical guidelines for journal publication see
http://www.elsevier.com/publishingethics
and
http://www.elsevier.com/ethicalguidelines.
Policy and ethics
The work
described in your article must have been carried out in accordance with
The Code of Ethics of the World Medical Association (Declaration
of Helsinki) for experiments involving humans 
http://www.wma.net/en/30publications/10policies/b3/index.html;
EU
Directive 2010/63/EU for animal experiments http://ec.europa.eu/environment/chemicals/lab_animals/legislation_en.htm;
Uniform Requirements for manuscripts submitted to Biomedical journals http://www.icmje.org. This must be stated
at an appropriate point in the article.
Conflict of interest
All authors are requested to
disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations
within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See
also
http://www.elsevier.com/conflictsofinterest.
Submission declaration
Submission
of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published
lecture or academic thesis), that it is not under consideration for publication elsewhere, that its publication is approved by all authors
and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published
elsewhere including electronically in the same form, in English or in any other language, without the written consent of the copyright-holder.
Contributors
Each author is required to declare his or her individual contribution to the article: all authors
must have materially participated in the research and/or article preparation, so roles for all authors should be described. The statement
that all authors have approved the final article should be true and included in the disclosure.
Changes
to authorship
This policy concerns the addition, deletion, or rearrangement of author names in the authorship of accepted
manuscripts:
Before the accepted manuscript is published in an online issue: Requests to add or remove an author, or to rearrange
the author names, must be sent to the Journal Manager from the corresponding author of the accepted manuscript and must include: (a)
the reason the name should be added or removed, or the author names rearranged and (b) written confirmation (e-mail, fax, letter) from
all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes
confirmation from the author being added or removed. Requests that are not sent by the corresponding author will be forwarded by the
Journal Manager to the corresponding author, who must follow the procedure as described above. Note that: (1) Journal Managers will inform
the Journal Editors of any such requests and (2) publication of the accepted manuscript in an online issue is suspended until authorship
has been agreed.
After the accepted manuscript is published in an online issue: Any requests to add, delete, or rearrange
author names in an article published in an online issue will follow the same policies as noted above and result in a corrigendum.
Copyright
Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement'
(for more information on this and copyright see
http://www.elsevier.com/copyright). Acceptance of the agreement will ensure
the widest possible dissemination of information. An e-mail will be sent to the corresponding author confirming receipt of the manuscript
together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
Subscribers may reproduce
tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of
the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations
and translations (please consult
http://www.elsevier.com/permissions). If excerpts from other copyrighted works are included,
the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted
forms for use by authors in these cases: please consult
http://www.elsevier.com/permissions.
Retained
author rights
As an author you (or your employer or institution) retain certain rights; for details you are referred to:
http://www.elsevier.com/authorsrights.
Role of the funding source
You are requested
to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe
the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report;
and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated.
Please see
http://www.elsevier.com/funding.
Funding body agreements and policies
Elsevier
has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply
with potential manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements
and policies please visit
http://www.elsevier.com/fundingbodies.
Open access
This
journal offers you the option of making your article freely available to all via the ScienceDirect platform. To prevent any conflict
of interest, you can only make this choice after receiving notification that your article has been accepted for publication. The fee
of $3,000 excludes taxes and other potential author fees such as color charges. In some cases, institutions and funding bodies have entered
into agreement with Elsevier to meet these fees on behalf of their authors. Details of these agreements are available at
http://www.elsevier.com/fundingbodies.
Authors of accepted articles, who wish to take advantage of this option, should complete and submit the order form (available at
http://www.elsevier.com/locate/openaccessform.pdf).
Whatever access option you choose, you retain many rights as an author, including the right to post a revised personal version of your
article on your own website. More information can be found here:
http://www.elsevier.com/authorsrights.
Language and language services
Please write your text in good English (American or British usage is accepted,
but not a mixture of these). Authors who require information about language editing and copyediting services pre- and post-submission
please visit
http://webshop.elsevier.com/languageservices
or our customer support site at
http://support.elsevier.com
for more information.
Submission
Submission to this journal proceeds totally online and
you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a single
PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted
to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence,
including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.
Additional information
Papers focused on the actions of drugs are beyond the scope of the journal.
Manuscripts
will be evaluated by a member of the board of editors of the Journal, and a panel of international reviewers. An editorial decision will
normally be made within 4 weeks of receipt of the manuscript, and publication will normally take place within 3 months of final acceptance.
Essential title page information for all articles
-
Title.
Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.
-
Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly.
Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case
superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each
affiliation, including the country name, and, if available, the e-mail address of each author.
-
Corresponding author.
Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that telephone
and fax numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address.
-
Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the
time, a " Present address" (or " Permanent address" ) may be indicated as a footnote to that author's name. The
address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are
used for such footnotes.
Abstract
This must not exceed 300 words and should be subdivided into four
subsections headed: Introduction, Methods, Results, Discussion.
Keywords
Immediately after the abstract, provide a
maximum of 10 keywords (one of which should be "methods") in alphabetical order, using British spelling and avoiding general and plural
terms and multiple concepts (avoid, for example, " and" , " of" ). Be sparing with abbreviations: only abbreviations firmly established
in the field may be eligible. These keywords will be used for indexing purposes.
Abbreviations
Define abbreviations
that are not standard in the field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable
in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout
the article.
Specific instructions for "regular articles":
Introduction
This must outline the reason
for the study and justify the approach taken.
Methods
This section should be sufficiently detailed
to permit the reader to replicate the study. It should be a full recipe, with step by step instructions. We prefer the bulk of the descriptions
in prose, but tables summarising sequences of procedures are a good accompaniment to the text. Subcomponents of the method that have
been described in detail in the literature should be described in full, but appropriate citation of the original source method is mandatory.
Results
This section should be concise and must not contain repetition of the methods. Data in the text must not replicate data
in tables or figures. SI units must be used.
Discussion
The potential value of the data to pharmacological or toxicological
research methods must be clearly explained, with appropriate reference to existing methods and their limitations. This section must not
contain paragraphs dealing with topics that are beyond the scope of the study.
Specific instructions for "How To"
articles:
" How To" articles that provide step-by-step guidance on the execution of specific techniques.
Introduction
For "How To" articles, this section will be very brief, and will simply identify the therapeutic area,
the goal of the method, and give mention to published (less detailed, presumably) descriptions if available. It is unlikely that many
papers will be cited in this section.
Methods
This section should be sufficiently detailed to permit the reader to replicate
the study. It should be a full recipe, with step by step instructions. I prefer the bulk of the descriptions in prose, but tables summarising
sequences of procedures are a good accompaniment to the text. Subcomponents of the method that have been described in detail in the literature
should be described in full, but appropriate citation of the original source method is mandatory.
Results
This section should be concise and must not contain repetition of the methods. Data in the text must not replicate data in tables or
figures. SI units must be used. For How To articles, some representative data showing that the recipe works is essential. It would be
especially useful, too, if data is contrasted with that using other methods (if no author-derived comparative data is available, please
reproduce data from the literature in a table, citing the source). It is essential for the reader to know that the method works, and
works well.
Discussion
The potential value of the data to pharmacological or toxicological research methods must be clearly
explained, with appropriate reference to existing methods and their limitations. This section must not contain paragraphs dealing with
topics that are beyond the scope of the study.
Specific instructions for "Appraisal of State of the Art"-articles:
Appraisal articles are reviews about the current best models. The review needs to describe the current best model, and discuss the evidence
(or lack of) to support the idea that the model is good. A good model should demonstrably detect drugs that work (or cause adverse effects)
in man, and demonstrably have few false positives or negatives. This evidence should be presented. The review should contrast the current
best model with other available but inferior models, thereby illustrating why one is the state-of-the-art model.
Text to be divided
into sections according to author choice.
Specific instructions for "Historical review" articles:
Historical
reviews can be more personal and less formal. Senior figures in a field may have decades of experience with models, methods, techniques
of apparatus. It is of immense value and interest to the research community to learn the history of the development of a model, understand
why one model was abandoned and another developed, and get insight into the thinking behind a model, and the impact of good and bad models
in drug development in a particular field. In addition, in many fields many models are still used that are transparently inadequate -
it would be of great value to obtain a candid expose from an experienced practitioner as to why this might be, including insight into
personal perspective as it changed over the years.
Text to be divided into sections according to author choice
Specific
instructions for "Methods in drug discovery" articles:
These articles are specifically intended to showcase, for
the wider audience, exactly how methods were applied by a pharmaceutical company in the preclinical development of one of their own drugs.
While it is appreciated that companies may wish to keep certain information confidential, it would be of great interest to the reader
to be able to understand the logic (or lack of) behind the choice of each preclinical test used in the drug's development. Demonstration
that use of a series of models, methods, techniques and apparatus gave rise to a drug that works in man is the closest we can get to
a methods validation - a much neglected area. The reader would also benefit by having revealed the logic behind the decision-making that
allowed the successful drug to proceed in development, while analogues and other compounds were dropped. Consideration of whether this
decision was making based on proof, or on the exercise of judgement, or a mixture of both will be of value to the author as well as the
reader as it will identify weak areas in the process for future improvements in pharmacological and toxicological methods.
Text
to be divided into the following sections
- Brief overview of evidence that drug X is
now established as being clinically effective
- Original hypothesis that triggered the search for a drug if type X
- Preclinical models used in defining drug X's properties (subsections in sequence, explaining logic behind choice)
-
Outcome of tests (subsections in sequence, explaining logic behind successive decision making)
- Conclusions
Specific instructions for all articles:
Acknowledgements
Collate acknowledgements
in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote
to the title or otherwise. List here those individuals who provided help during the research (e.g., providing language help, writing
assistance or proof reading the article, etc.).
Database linking
Elsevier aims at connecting
online articles with external databases which are useful in their respective research communities. If your article contains relevant
unique identifiers or accession numbers (bioinformatics) linking to information on entities (genes, proteins, diseases, etc.) or structures
deposited in public databases, then please indicate those entities according to the standard explained below.
Authors should explicitly
mention the
database abbreviation (as mentioned below) together with the actual database number, bearing in mind that an error
in a letter or number can result in a dead link in the online version of the article.
Please use the following format:
Database
ID: xxxx
Links can be provided in your online article to the following databases (examples of citations are given in parentheses):
•
ASTM: ASTM Standards Database (ASTM ID: G63)
•
CCDC:
Cambridge Crystallographic Data Centre (CCDC ID: AI631510)
•
GenBank:
Genetic sequence database at the National Center for Biotechnology Information (NCBI) (GenBank ID: BA123456)
•
GEO:
Gene Expression Omnibus (GEO ID: GSE27196; GEO ID: GPL5366; GEO ID: GSM9853)
•
MI:
EMBL-EBI OLS Molecular Interaction Ontology (MI ID: 0218)
•
MINT:
Molecular INTeractions database (MINT ID: 6166710)
•
NCBI Taxonomy:
NCBI Taxonomy Browser (NCBI Taxonomy ID: 48184)
•
NCT: ClinicalTrials.gov
(NCT ID: NCT00222573)
•
OMIM: Online Mendelian Inheritance
in Man (OMIM ID: 601240)
•
PDB: Worldwide Protein Data
Bank (PDB ID: 1TUP)
•
TAIR: The Arabidopsis Information Resource
database (TAIR ID: AT1G01020)
•
UniProt: Universal Protein Resource
Knowledgebase (UniProt ID: Q9H0H5)
Math formulae
Present simple formulae in the line of
normal text where possible and use the solidus (/) instead of a horizontal line for small fractional terms, e.g., X/Y. In principle,
variables are to be presented in italics. Powers of e are often more conveniently denoted by exp. Number consecutively any equations
that have to be displayed separately from the text (if referred to explicitly in the text).
Footnotes
Footnotes
should be used sparingly. Number them consecutively throughout the article, using superscript Arabic numbers. Many wordprocessors build
footnotes into the text, and this feature may be used. Should this not be the case, indicate the position of footnotes in the text and
present the footnotes themselves separately at the end of the article. Do not include footnotes in the Reference list.
Table
footnotes
Indicate each footnote in a table with a superscript lowercase letter.
Artwork
Electronic artwork
General points
• Make sure you use uniform lettering and sizing of your
original artwork.
• Save text in illustrations as 'graphics' or enclose the font.
• Only use the following fonts in
your illustrations: Arial, Courier, Times, Symbol.
• Number the illustrations according to their sequence in the text.
•
Use a logical naming convention for your artwork files.
• Provide captions to illustrations separately.
• Produce images
near to the desired size of the printed version.
• Submit each figure as a separate file.
A detailed guide on electronic
artwork is available on our website:
http://www.elsevier.com/artworkinstructions
You are urged to visit this
site; some excerpts from the detailed information are given here.
Formats
Regardless of the application used, when
your electronic artwork is finalised, please 'save as' or convert the images to one of the following formats (note the resolution requirements
for line drawings, halftones, and line/halftone combinations given below):
EPS: Vector drawings. Embed the font or save the text
as 'graphics'.
TIFF: Color or grayscale photographs (halftones): always use a minimum of 300 dpi.
TIFF: Bitmapped line drawings:
use a minimum of 1000 dpi.
TIFF: Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required.
If
your electronic artwork is created in a Microsoft Office application (Word, PowerPoint, Excel) then please supply 'as is'.
Please
do not:
• Supply files that are optimised for screen use (e.g., GIF, BMP, PICT, WPG); the resolution is too low;
•
Supply files that are too low in resolution;
• Submit graphics that are disproportionately large for the content.
Color artwork
Please make sure that artwork files are in an acceptable format (TIFF, EPS or MS Office files)
and with the correct resolution. If, together with your accepted article, you submit usable color figures then Elsevier will ensure,
at no additional charge, that these figures will appear in color on the Web (e.g., ScienceDirect and other sites) regardless of whether
or not these illustrations are reproduced in color in the printed version.
For color reproduction in print, you will receive information
regarding the costs from Elsevier after receipt of your accepted article. Please indicate your preference for color: in print or
on the Web only. For further information on the preparation of electronic artwork, please see
http://www.elsevier.com/artworkinstructions.
Please note: Because of technical complications which can arise by converting color figures to 'gray scale' (for the printed version
should you not opt for color in print) please submit in addition usable black and white versions of all the color illustrations.
Figure captions
Ensure that each illustration has a caption. Supply captions separately, not attached to the
figure. A caption should comprise a brief title (
not on the figure itself) and a description of the illustration. Keep text in
the illustrations themselves to a minimum but explain all symbols and abbreviations used.
Tables
Number
tables consecutively in accordance with their appearance in the text. Place footnotes to tables below the table body and indicate them
with superscript lowercase letters. Avoid vertical rules. Be sparing in the use of tables and ensure that the data presented in tables
do not duplicate results described elsewhere in the article.
References
Citation
in text
Please ensure that every reference cited in the text is also present in the reference list (and vice versa). Any
references cited in the abstract must be given in full. Unpublished results and personal communications are not recommended in the reference
list, but may be mentioned in the text. If these references are included in the reference list they should follow the standard reference
style of the journal and should include a substitution of the publication date with either 'Unpublished results' or 'Personal communication'.
Citation of a reference as 'in press' implies that the item has been accepted for publication.
Web references
As
a minimum, the full URL should be given and the date when the reference was last accessed. Any further information, if known (DOI, author
names, dates, reference to a source publication, etc.), should also be given. Web references can be listed separately (e.g., after the
reference list) under a different heading if desired, or can be included in the reference list.
References
in a special issue
Please ensure that the words 'this issue' are added to any references in the list (and any citations
in the text) to other articles in the same Special Issue.
Reference management software
This
journal has standard templates available in key reference management packages EndNote (
http://www.endnote.com/support/enstyles.asp)
and Reference Manager (
http://refman.com/support/rmstyles.asp). Using plug-ins to wordprocessing packages, authors only
need to select the appropriate journal template when preparing their article and the list of references and citations to these will be
formatted according to the journal style which is described below.
Reference style
Text:
Citations in the text should follow the referencing style used by the American Psychological Association. You are referred to the Publication
Manual of the American Psychological Association, Sixth Edition, ISBN 978-1-4338-0561-5, copies of which may be ordered from
http://books.apa.org/books.cfm?id=4200067
or APA Order Dept., P.O.B. 2710, Hyattsville, MD 20784, USA or APA, 3 Henrietta Street, London, WC3E 8LU, UK. Details concerning this
referencing style can also be found at
http://linguistics.byu.edu/faculty/henrichsenl/apa/apa01.html.
List:
references should be arranged first alphabetically and then further sorted chronologically if necessary. More than one reference from
the same author(s) in the same year must be identified by the letters 'a', 'b', 'c', etc., placed after the year of publication.
Examples:
Reference to a journal publication:
Van der Geer, J., Hanraads, J. A. J., & Lupton, R. A. (2010). The art of writing a scientific
article.
Journal of Scientific Communications, 163, 51–59.
Reference to a book:
Strunk, W., Jr., &
White, E. B. (2000).
The elements of style. (4th ed.). New York: Longman, (Chapter 4).
Reference to a chapter in an edited
book:
Mettam, G. R., & Adams, L. B. (2009). How to prepare an electronic version of your article. In B. S. Jones, & R. Z.
Smith (Eds.),
Introduction to the electronic age (pp. 281–304). New York: E-Publishing Inc.
Journal
abbreviations source
Journal names should be abbreviated according to
Index Medicus journal abbreviations:
http://www.nlm.nih.gov/tsd/serials/lji.html;
List of title word abbreviations:
http://www.issn.org/2-22661-LTWA-online.php;
CAS (Chemical Abstracts Service):
http://www.cas.org/sent.html.
Video data
Elsevier accepts video material and
animation sequences to support and enhance your scientific research. Authors who have video or animation files that they wish to submit
with their article are strongly encouraged to include these within the body of the article. This can be done in the same way as a figure
or table by referring to the video or animation content and noting in the body text where it should be placed. All submitted files should
be properly labeled so that they directly relate to the video file's content. In order to ensure that your video or animation material
is directly usable, please provide the files in one of our recommended file formats with a preferred maximum size of 50 MB. Video and
animation files supplied will be published online in the electronic version of your article in Elsevier Web products, including ScienceDirect:
http://www.sciencedirect.com. Please supply 'stills' with your files: you can choose any frame from the video or animation
or make a separate image. These will be used instead of standard icons and will personalize the link to your video data. For more detailed
instructions please visit our video instruction pages at
http://www.elsevier.com/artworkinstructions. Note: since video
and animation cannot be embedded in the print version of the journal, please provide text for both the electronic and the print version
for the portions of the article that refer to this content.
Supplementary data
Elsevier
accepts electronic supplementary material to support and enhance your scientific research. Supplementary files offer the author additional
possibilities to publish supporting applications, high-resolution images, background datasets, sound clips and more. Supplementary files
supplied will be published online alongside the electronic version of your article in Elsevier Web products, including ScienceDirect:
http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please provide the data
in one of our recommended file formats. Authors should submit the material in electronic format together with the article and supply
a concise and descriptive caption for each file. For more detailed instructions please visit our artwork instruction pages at
http://www.elsevier.com/artworkinstructions.
Submission checklist
The following list will be useful during the final checking of an article prior to sending
it to the journal for review. Please consult this Guide for Authors for further details of any item.
Ensure that the following
items are present:
One author has been designated as the corresponding author with contact details:
• E-mail address
• Full postal address
• Telephone and fax numbers
All necessary files have been uploaded, and contain:
•
Keywords
• All figure captions
• All tables (including title, description, footnotes)
Further considerations
•
Manuscript has been 'spell-checked' and 'grammar-checked'
• References are in the correct format for this journal
•
All references mentioned in the Reference list are cited in the text, and vice versa
• Permission has been obtained for use
of copyrighted material from other sources (including the Web)
• Color figures are clearly marked as being intended for color
reproduction on the Web (free of charge) and in print, or to be reproduced in color on the Web (free of charge) and in black-and-white
in print
• If only color on the Web is required, black-and-white versions of the figures are also supplied for printing purposes
For any further information please visit our customer support site at
http://support.elsevier.com.
Use of the Digital
Object Identifier
The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists
of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication.
The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they
have not yet received their full bibliographic information. The correct format for citing a DOI is shown as follows (example taken from
a document in the journal
Physics Letters B):
doi:10.1016/j.physletb.2010.09.059
When you use the DOI to create URL
hyperlinks to documents on the web, the DOIs are guaranteed never to change.
Proofs
One
set of page proofs (as PDF files) will be sent by e-mail to the corresponding author (if we do not have an e-mail address then paper
proofs will be sent by post) or, a link will be provided in the e-mail so that authors can download the files themselves. Elsevier now
provides authors with PDF proofs which can be annotated; for this you will need to download Adobe Reader version 7 (or higher) available
free from
http://get.adobe.com/reader. Instructions on how to annotate PDF files will accompany the proofs (also given online).
The exact system requirements are given at the Adobe site:
http://www.adobe.com/products/reader/tech-specs.html.
If
you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and return them
to Elsevier in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then mark the corrections
and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail,
or by post. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures.
Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor.
We will do everything possible to get your article published quickly and accurately – please let us have all your corrections within
48 hours. It is important to ensure that all corrections are sent back to us in one communication: please check carefully before replying,
as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed
with the publication of your article if no response is received.
Offprints
The corresponding
author, at no cost, will be provided with a PDF file of the article via e-mail. For an extra charge, paper offprints can be ordered via
the offprint order form which is sent once the article is accepted for publication. The PDF file is a watermarked version of the published
article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use.
For inquiries relating to the submission of articles (including electronic submission) please
visit this journal's homepage. Contact details for questions arising after acceptance of an article, especially those relating to proofs,
will be provided by the publisher. You can track accepted articles at
http://www.elsevier.com/trackarticle. You can also
check our Author FAQs (
http://www.elsevier.com/authorFAQ) and/or contact Customer Support via
http://support.elsevier.com.
