Official Journal of EUROTOX An international journal for the rapid publication of short reports on all aspects of toxicology, especially mechanisms of toxicity
Guide for Authors
An international journal for the rapid publication of short reports on all aspects of toxicology, especially mechanisms of toxicity. Toxicology
Letters also publishes mini-reviews, editorials, commentaries and contemporary issues in toxicology.
General guidelines
The journal focuses on the rapid publication of novel results and prefers short manuscripts on all aspects of toxicology although longer
manuscripts
will be considered. Preference is given to studies that are relevant to mechanistic toxicology and hypothesis-driven. The
rationale should
be sound, and the experimental design should be well-conceived. Completeness usually requires that dose-response relationships
are examined.
Manuscripts that primarily describe new methods, either experimental or theoretical, should provide examples of their use.
When studies involve
the use of experimental animals, manuscripts should briefly describe the procedures employed for animal care and
handling. Experiments that
require the use of animals or humans must be conducted in accordance with International Guidelines.
Non-hypothesis-driven
studies (e.g. safety evaluation of new chemicals or drugs) may be published if the work is considered complete
and the conclusions are
unequivocal. Studies that fail to elicit a toxic response (negative studies) might be acceptable if competently
performed.
A manuscript
may be declined for reasons of ethical considerations, incompleteness, insufficient quality, prior publication of portions of the
work,
inadequate experimental design or methods, inadequate description of experiments, of insufficient support for conclusions, or subject
matter not consistent with the mission of the journal.
Manuscripts are accepted for review with the understanding that the same work
has not been published, that it is not under consideration for
publication elsewhere, and that its submission for publication has been
approved by all of the authors and by the institution where the work was
carried out. Further, it is understood that any person cited
as a source of personal communications has approved such citation.
Authors submitting a manuscript do so on the understanding that
if it is accepted for publication, copyright in the article, including the right to
reproduce the article in all forms and media, shall
be assigned exclusively to Elsevier, unless legally prohibited (e.g. U.S. Federal government
employees).
Duties of Authors
Reporting standards. Authors of reports of original research should present an accurate account of the work performed as well
as an objective discussion of its significance. Underlying data should be represented accurately in the paper. A paper should contain
sufficient detail and references to permit others to replicate the work. Fraudulent or knowingly inaccurate statements constitute unethical
behavior and are unacceptable. Review and professional publication articles should also be accurate and objective, and editorial
opinion works should be clearly identified as such.
Data Access and Retention. Authors may be asked to provide the raw data
in connection with a paper for editorial review, and should be prepared to provide public access to such data (consistent with the ALPSP-STM
Statement on Data and Databases), if practicable, and should in any event be prepared to retain such data for a reasonable time after
publication.
Originality and Plagiarism. The authors should ensure that they have written entirely original works, and if
the authors have used the work and/or words of others, that this has been appropriately cited or quoted. Plagiarism takes many forms,
from passing off another s paper as the author s own paper, to copying or paraphrasing substantial parts of another s paper (without
attribution), to claiming results from research conducted by others. Plagiarism in all its forms constitutes unethical publishing behavior
and is unacceptable.
Multiple, Redundant or Concurrent Publication. An author should not in general publish manuscripts
describing essentially the same research in more than one journal or primary publication. Submitting the same manuscript to more than
one journal concurrently constitutes unethical publishing behaviour and is unacceptable. In general, an author should not submit for
consideration in another journal a previously published paper. Publication of some kinds of articles (eg, clinical guidelines, translations)
in more than one journal is sometimes justifiable, provided certain conditions are met. The authors and editors of the journals concerned
must agree to the secondary publication, which must reflect the same data and interpretation of the primary document. The primary reference
must be cited in the secondary publication. Further detail on acceptable forms of secondary publication can be found at www.icmje.org.
Acknowledgement of Sources. Proper acknowledgment of the work of others must always be given. Authors should cite publications
that have been influential in determining the nature of the reported work. Information obtained privately, as in conversation, correspondence,
or discussion with third parties, must not be used or reported without explicit, written permission from the source. Information obtained
in the course of confidential services, such as refereeing manuscripts or grant applications, must not be used without the explicit written
permission of the author of the work involved in these services.
Authorship of the Paper. Authorship should be limited to
those who have made a significant contribution to the conception, design, execution, or interpretation of the reported study. All those
who have made significant contributions should be listed as co-authors. Where there are others who have participated in certain substantive
aspects of the research project, they should be acknowledged or listed as contributors. The corresponding author should ensure that
all appropriate co-authors and no inappropriate co-authors are included on the paper, and that all co-authors have seen and approved
the final version of the paper and have agreed to its submission for publication.
Hazards and Human or Animal Subjects. If
the work involves chemicals, procedures or equipment that have any unusual hazards inherent in their use, the author must clearly identify
these in the manuscript. If the work involves the use of animal or human subjects, the author should ensure that the manuscript contains
a statement that all procedures were performed in compliance with relevant laws and institutional guidelines and that the appropriate
institutional committee(s) have approved them. Authors should include a statement in the manuscript that informed consent was obtained
for experimentation with human subjects. The privacy rights of human subjects must always be observed.
Conflict of Interest and
Source of Funding. A conflict of interest exists when an author or the author?s institution has a financial or other
relationship
with other people or organizations that may inappropriately influence the author's actions. All submissions to Toxicology Letters
must include disclosure of all relationships that could be viewed as presenting a potential conflict of interest. Toxicology Letters
may use such
information as a basis for editorial decisions and may publish such disclosures if they are believed to be important to
readers in judging the
article.
Conflict of Interest Statements for Authors. The Journal requires full disclosure of all potential
conflicts of interest. At the end of the text, under a subheading "Conflict of Interest Statement", all authors must disclose any financial,
personal, or their relationships with other people or organizations within 3 years of beginning the work submitted that could inappropriately
influence the work submitted. Examples of conflicts include employment, consultancies, stock ownership, honoraria, paid expert testimony,
patent applications/registrations, and grants. If there are no conflicts of interest, the authors should state, "The authors declare
that there are no conflicts of interest." Investigators should disclose potential conflicts to participants in clinical trials and other
studies and should state in the manuscript whether they have done so. Toxicology Letters may decide not to publish on the basis
of a declared conflict, such as the financial interest of an author in a company (or its competitors) that makes a product discussed
in the paper. Signed copies of the Toxicology Letters Conflict of Interest policy form are required upon submission. The Conflict
of Interest policy form can be downloaded here. In order to
minimize delays, we strongly advise that the signed copies of these statements are prepared before you submit your manuscript. The corresponding
author is responsible for sharing this document with all co-authors. Each and every co-author must sign an individual disclosure form.
The corresponding author is responsible for uploading their form and those of their co-authors.
Manuscripts
Manuscripts
should be typewritten, 1.5-spaced and should be in English. References should be single spaced. In general, manuscripts should
not be
longer than 10 printed pages (approx. 15, 1.5-spaced typewritten pages) including the space needed for illustrations.
Manuscripts
must be submitted for review via the Elsevier website (http://ees.elsevier.com/)
toxlet). Submissions that are emailed, or mailed, to the editors will not be considered. Questions about submissions may be directed
to the
appropriate editor.
English language help service: Upon request, Elsevier will direct authors to an agent who can check and improve the English of
their paper
(before submission). Please contact authorsupport@elsevier.com for further information.
Mini-review
papers
These papers should be approximately 12-15, 1.5-spaced typewritten pages; should be in English and submitted via the Internet
on the Elsevier website (http://ees.elsevier.com/toxlet). The reference
list need not be exhaustive, but should include the most
significant articles. The names of two potential reviewers are also requested.
Revised versions
The medium of submission for revised papers is electronically through the Elsevier website (http://ees.elsevier.com/. Figures should be submitted as original high quality files of a standard graphics program. Revised versions should be returned
within 3
months of the first date of decision. Failure to do so may result in any resubmission being treated as a new version and carrying
a new date of
receipt.
Address
Authors' full names, academic or professional affiliations and addresses should be included
on the first page. The name and complete address
and e-mail address of the author to whom any correspondence is to be sent should be
given.
Key words
A list of 3-6 words or short phrases suitable for use in Index should be included on the first page. These
terms will be printed with the paper
below the Abstract. In the event that key words are not supplied editorial discretion will be exercised
in introducing appropriate words.
Abstract
The article should start with an Abstract of about 150 - 200 words.
Figures
Figures should be provided as high quality electronic files using standard software. Color should only be used when scientifically necessary.
The cost of publishing in color is 350 Euro for the first page, 175 Euro for each subsequent page.
Tables
Tables should
be numbered with Arabic numbers and bear a short descriptive title. Each table should be typed on a separate sheet.
Gene accession
numbers
In the electronic version of a published manuscript, gene accession numbers will be linked directly to the gene's description
in NCBI's
Nucleotide sequence database. The accession number should formatted as follows:
Accession no. AJ315850
The production
department will then link this reference when they find it in the text. Authors should DOUBLE-CHECK the number they use
to make absolutely
sure that it is correct before referring to it in their paper. Accession numbers in proofs should also always be checked for
correctness.
The number is an essential part of the link.
References
References should be typed on a separate sheet of paper. The list
of references should be arranged alphabetically by authors' names, and
chronologically per author. In the text, refer to the author's
name (without initial) and year of publication. Literature references must consist of
names and initials of all authors, year, title
of paper, abbreviated title of periodical and the volume, and first and last page numbers of the paper.
References should be limited
to 50 or less.
'Unpublished results' and 'personal communication' should not be included in the reference list as they are of little
use to the reader but they
may be cited as such in the text. The abbreviation of journal titles should conform to those adopted by List
of Serial Title Work Abbreviations
(International Serials Data System, International Organization for Standardization, 20, rue Bachaumont,
75002 Paris, France, ISBN 2-904938-
02-8). In the reference list, periodicals, books, and edited books should accord with the following
examples:
Hancock, K., Tsang, V.C.W., 1983. India ink staining of proteins on nitrocellulose paper. Anal. Biochem. 133, 157-162.
Metcalf, D., 1984. The Hemopoietic Colony Stimulating Factors. Elsevier, Amsterdam, pp. 173-185.
Hamor, T.A., Martin, I.L., 1983.
The benzodiazepines. In: Ellis, G.P., West, G.B. (Eds.), Progress in Medicinal Chemistry, col. 20. Elsevier,
Amsterdam, pp. 157?223.
Proof reading
Proofs will be supplied electronically for the author to check for typesetting accuracy. Only printer's errors
may be corrected; no changes to
the original manuscript will be allowed at this stage.
Inquiries regarding accepted manuscripts should
be addressed to: Toxicology Letters, Elsevier Ireland Ltd., Elsevier House, Bookvale Plaza,
East Plaza, Bay 15, Shannon Industrial
Estate, Shannon, Co. Clare, Ireland. Tel.: (+353-61)709600; Fax: (+353-61)709109.
Reprints
A total of 25 reprints of each
paper will be provided free of charge. Additional copies may be ordered at prices shown on the reprint order form
which will be sent
to the author.
US National Institutes of Health (NIH) voluntary posting (" Public Access") policy
Elsevier facilitates author
response to the NIH voluntary posting request (referred to as the NIH "Public Access Policy"; see http://www.nih.gov/about/publicaccess/index.htm) by posting the peer-reviewed author's manuscript directly to PubMed Central on request from the author,
12 months after formal publication. Upon notification from Elsevier of acceptance, we will ask you to confirm via e-mail (by e-mailing
us at NIHauthorrequest@elsevier.com ) that your work has received NIH funding and that you intend to respond to the NIH
policy request, along with your NIH award number to facilitate processing. Upon such confirmation, Elsevier will submit to PubMed Central
on your behalf a version of your manuscript that will include peer-review comments, for posting 12 months after formal publication. This
will ensure that you will have responded fully to the NIH request policy. There will be no need for you to post your manuscript directly
with PubMed Central, and any such posting is prohibited.
Preparation of supplementary material
Elsevier now accepts electronic
supplementary material to support and enhance your scientific research. Supplementary files offer the author
additional possibilities
to publish supporting applications, movies, animation sequences, high-resolution images, background datasets, sounds
clips and more.
Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier web products,
including
ScienceDirect (http://www.sciencedirect.com). In order to ensure that
your submitted material is directly usable, please ensure that
data are provided in one of our recommended file formats. Files can be
stored on 3 inch diskette, ZIP-disk or CD (either MS-DOS or Macintosh).
Authors should submit the material in electronic format together
with the article and supply a concise and descriptive caption for each file. For
more detailed instructions please visit http://www.elsevier.com/authors.Toxicology Letters has no page charges.
