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JOURNAL OF FLUORINE CHEMISTRY

Guide for Authors

A PDF version of the full Instructions to Authors.


The Journal of Fluorine Chemistry contains original papers and short preliminary communications describing both pure and applied research on the chemistry and applications of fluorine, and of compounds where fluorine exercises significant effects. The Journal of Fluorine Chemistry covers inorganic, organic, organometallic and physical chemistry and also includes papers on biochemistry and environmental industrial chemistry. Preparative and physico-chemical investigations as well as theoretical, structural and mechanistic aspects are covered. Review papers and fluorine chemistry syntheses are also published, although it is useful to contact an Editor before preparing these. Papers are occasionally published from selected symposia; conference organizers should initially contact the Regional Editors for further details.

Abstracting services
Chemical Abstracts, Beilstein, Current Contents (ISI), PASCAL/CNRS, Periodicals Digest, Physikalische Berichte, Research AlertTM, Science Citation Index, World Translation Indexes, Chemical Safety Databases, RTECS (Registry of Toxic Effects of Chemical Substances).

Types of contributions
•Review papers
•Original papers not previously published
•Short communications
•Fluorine chemistry synthesis
•Papers from selected symposia

Submission of contributions
Online submission: Authors are encouraged to submit their manuscript to the appropriate Regional Editor via the online submission page of this journal at External link http://ees.elsevier.com/fluor/. Authors will be guided stepwise through the creation and uploading of the various files. The system automatically converts source files to a single Adobe Acrobat PDF version of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the editor's decision and requests for revision, takes place by e-mail and via the author's home page. A printed copy of the manuscript is not required at any stage of the process.

It is not necessary to embed graphics in the text on first submission, but if you do so please note that separate graphic files will always be required for proof production when a manuscript is accepted for publication. Graphics should be submitted as separate, high-resolution artwork files. These will be automatically incorporated into the single PDF that the system creates for review.

Alternatively, authors may submit three copies of their manuscript, one complete set of original illustrations and two copies to the Regional Editor in charge of their geographic area. If submitting by hard copy, for the final version, in addition to the original and two copies, authors should submit an electronic version of their manuscript on disc.

Europe, Africa and Australia:

Professor J. M. Winfield
Department of Chemistry
University of Glasgow
Joseph Black Building
Glasgow
G12 8QQ
UK
E-mail: johnwin@chem.gla.ac.uk
Fax: +44 (0)141 330 4888

Japan and Asia:

Prof. T. Taguchi
Tokyo University of Pharmacy and Life Science
Hachioji
Tokyo
192-0392
Japan
Phone: +81 426 76 3257
E-mail: taguchi@ps.toyaku.ac.jp

Americas:

Dr. W. R. Dolbier, Jr.
Department of Chemistry
P.O. Box 117200
University of Florida
Gainsville
FL32611-7200, USA
Phone: (352) 392-0591
Fax: (352) 846-1962
E-mail: wrd@chem.ufl.edu

Contributions are accepted on the understanding that the authors have obtained the necessary authority for publication and that the submitted manuscript is an original contribution that is not under consideration elsewhere.
Authors are reminded that delays in publication may occur if the instructions for submission and disk and manuscript preparation are not strictly followed. Authors are strongly recomended to submit online to aid rapid processing or if submitting by hard copy, authors are reminded to include discs. To facilitate communication, authors are requested to provide their current e-mail address, phone and fax number.

Editorial Authority. The Editors reserve the right to make alterations in manuscripts submitted for publication. Such alterations will be made if manuscripts do not conform with accepted scientific standards or if they contain matter which, in the opinion of the Editors, is unnecessarily wordy or unclear. If alterations are queried, this will inevitably delay publication. The revised manuscript must be returned to the Editors within one month, otherwise it maybe deemed to be new and subject to further review.

Preparation of manuscripts
General: Manuscripts must be typewritten, double-spaced with wide margins and a font size of 10 or 12 pt. The corresponding author should be identified (include a fax number and e-mail address). Full postal addresses must be given for all co-authors.
Most formatting codes will be removed from the text file, so there is no need to format it (e.g. do not use automatic word breaking, justified layout, double columns, paragraph numbering).
For online submission, prepare one file containing all your text, figures and tables with a file name extension. Follow the instructions in the online system, submitting first your complete file and then each graphic file separately.
For hardcopy submission, copies must be produced on a high-quality printer, and originals and copies of all Figures and Schemes must be fully legible. For the final version, an electronic copy of the paper on a floppy or CD should accompany the hard copy to the appropriate Editor. Make sure that the disk and the hard copy match exactly. Text and graphic files should be submitted on separate disks, and all files should be named with the correct file extension (Fig1.cdx, tb1-6.xls, text.doc, fig1a.eps, fig1.tif, etc). Label all disks with your name, Journal of Fluorine Chemistry, the software used (e.g. Word 97), compression software (if used), and what format the files are in (e.g. PC, Mac). Always keep a backup copy of the disks and manuscript for reference and safety since we cannot accept responsibility for damage or loss of papers. The Editors reserve the right to adjust the style to certain standards of uniformity. Original manuscripts are discarded one month after publication unless the Publisher is asked to return original material after use.

If authors are unfamiliar with the Journal of Fluorine Chemistry, they should consult a recent copy (e.g. the free electronic sample copy at http://www.elsevier.com/locate/fluor) to see the conventions currently followed. Note especially that the Experimental Section is placed at the end. The content of the manuscript must be arranged as follows: (1) a Graphical Abstract; (2) a Title Page with authors name(s) and address(es); (3) an Abstract, in which contents are briefly stated; (4) a Key Word Index, (5) Introduction, and (6) the Results and Discussion (preferably combined). Although each section may be seperated by headings, they should form one continuous narrative and only include details essential to the arguments presented. If a discussion is seperately provided, it should not include a repetition of results, but only indicate conclusions reached on the basis of them, and those from other referred works; (7) Conclusions or Concluding Remarks; (8) the Experimental should include brief details of the methods used such that a competent researcher in the field may be able to repeat the work; (9) Acknowledgments; (10) References and notes; (11) separate pages for Tables, Formulae, Figures and Legends.

Graphical Abstract: Authors must supply a Graphical Abstract at the time the paper is first submitted. The Graphical abstract should summarize the content of the paper in a concise pictorial form designed to capture the attention of a wide readership. Graphical Abstracts have purposefully been given much latitude in their design. For example, the pictorial form could be a chemical structure, a reaction, X-ray structure, or a graph. Ideally the graphic should be no larger than 65mm wide by 45mm high. The typesetter will insert the manuscript title, author(s), author(s) affiliation and address(es) and the page number. However, authors should ensure that these items along with the brief textual abstract (different to the full textual abstract) and the graphic do not exceed the space defined by the template given at the end of these instructions.

Title: Must be as brief as possible, but clearly explain the content of the article, and should ideally not exceed 10 words in length. If a paper is part of a series, this should be referred to in a footnote in the form:
*Part 9 in the series "Fluorinating reagents" followed by a numbered reference to the previous part.

Author's names: Each author should identify himself or herself with one forename, initials of other forenames and surname. This is to enable more exact computerized indexing and information retrieval. An asterisk should be placed following the name of the author to whom correspondence inquiries should be made. The corresponding author should include full details of telephone and fax numbers, and e-mail address(es). Symbols used should be a, b, c etc., in addition to the * for the corresponding author.

Institutional affiliations: Give the name(s) and address(es) of the institution(s) with which the authors were affiliated when the work was done.

Abstract: The abstract, distinct from the graphical abstract, should be on a seperate page and briefly describe the results obtained, and conclusions reached. The abstract is not expected to be a complete summary but should outline the main findings from the paper. The abstract should not be more than 250 words and should be readable without reference to the main paper.
For papers written in French or German, authors must provide an English version of the Abstract, in addition to the version in the language paper.

Keywords: Authors must give three to ten "key words" or phrases, which identify the most important subjects covered by the paper. Keywords should be selected, if appropriate, from the following classes: theoretical methods, experimental methods, phenomena, materials and applications. Chemical formulae (e.g. CF3CH2CO2H) should not be used as keywords.

1. Introduction
This should give the minimum historical data needed to give appropriate context to the author's investigation and its relationship to the other similar research previously or currently being conducted. Only information essential to the arguments should be presented. Much data can be taken for granted or quoted in abbreviated form.

2. Results and Discussion
These sections should be carefully prepared with discussions of the results being compared with existing and/or previous knowledge within the field. Authors are, however, encouraged to combine the Results and Discussion sections wherever possible.

3. Experimental
The Experimental should begin with a subsection entitled General Experimental Procedures, which will typically contain brief details of instruments used, safety procedures, health warnings and identification of sources of specialized chemicals. Subsections on Experimental Procedures should be italicized and inserted as part of the first line of the text to which they apply. Where applicable these subsections should also include boldface compound numbers (see examples below):
"Telomerisation of trifluoroethene with acetone"
"2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-D-arabinofuranose (3)"

The Experimental Procedures employed should be concise but sufficiently detailed that a qualified researcher will be able to repeat the studies undertaken, and these should emphasize either truly new procedures or essential modifications of existing procedures. Experimental details normally omitted include: (1) method of preparation of common chemical derivatives, (2) excessive details of separation of compounds, e.g. preparation of columns, TLC plates, column and fraction size.

Nomenclature. Chemical nomenclature, abbreviations and symbols must follow IUPAC rules. Whenever possible, avoid coining new trivial names; every effort should be made to modify an existing name. For example, when a new compound is described, it should be given a full systematic name according to IUPAC nomenclature (http://www.chem.qmul.ac.uk/iupac/) and this should be cited in the Abstract or in the Experimental section. Isotopically-labelled substances should be written with the correct chemical name of the compound. The symbol for the isotope should be placed in square brackets and should precede that part of the name to which it refers, e.g. sodium [14C]formate, trifluoroacetyl[18F]fluoride.

Use of abbreviations. The Journal of Fluorine Chemistry encourages extensive use of abbreviations in the experimental section, but not in the Introduction or Results and discussion sections, abbreviations should be employed liberally to economize on space. For the names of reagents, solvents, molecular formulae, abbreviations can be used, and these are preferred over acronyms, e.g., NaHCO3, Et2O, Me2SO (not DMSO), H18F, HOAc (not HAc), NaOAc. Abbreviations can also be substituted for common terms such as aqueous (aq), saturated (satd), etc. Units of measure [mL, cm, °, h (hour), etc.] are almost always abbreviated. For a list of allowable abbreviations, consult The ACS Style Guide or previous issues of the Journal.

Compound Characterization: Physical and spectroscopic data for new compounds must be comprehensive, and follow the order shown below: compound name (and assigned number in text); physical state of compound (e.g. oil, crystal, liquid, etc.), melting and/or boiling point (if applicable); optical rotation [α] D and/or circular dichoism measurements (if opticaly active); UV, IR, 1H NMR, 13C NMR, 19F NMR, MS. For all new compounds, either high-resolution mass spectral or elemental analysis data is required. "...gave needles: mp 83-85 °C; [α] D 25 -110° (c 1.4, CHC13); IR (KBr); v 1730(s) and 1260 (ester), 860 and 840 (Me3Si), and 710(m) cm-1 (Ph); 1H NMR..."

NMR spectral data should only be presented in full if they have not been published separately elsewhere, in which case only relevant references should be quoted. Data must be specified as 1H NMR, 13C NMR or 19F NMR and should indicate the frequency of the instrument, the solvent used and the enternal standard. Chemical shifts should be quoted in δ units relative to TMS with indication of whether the signal is a singlet s, doublet d, doublet of doublets dd, triplet t, multiplet m, etc. 13C NMR spectral data should specify the carbon concerned, using the recommended IUPAC numbering (e.g. C-1, C-2), and should be given to one decimal place. For example:
13C NMR (25.15 MHz, CDC13): δ 30.1 (t, C-5), 74.1 (d, C-6), 121.7 (d, C-3), 144.2 (s, C-4)
1H NMR spectral data (100 MHz, CDC13): δ 0.68 (3H, s, H-18), 0.88 (6H, d, J= 6 Hz, H-26 and H-27), 0.90 (3H, d, J= 5 Hz, H-21), 4.34 (1H, q, J6α, 7α= 4.5 Hz, J6α, 7β=2Hz, H-6), 4.21 (1H, m, W1/2 = 18Hz, H-3α).
19F NMR (56.4MHz, CC13F): δ -88.0 (m, 1F, NF), -68.3 (dt, 3F, J=13.5 Hz, CF3N), -82.0 (tt, 3F, J= 133.5 Hz, CF2,CF2,CF2,CF3 ).

Mass spectral data should only be presented in full if they have not been published separately elsewhere, in which case only relevant references should be quoted. Presentation of mass spectral data indicate the method used (EIMS, CIMS, GC-MS, etc.) and the ionizing energy. The data should give only diagnostically important ions, the character of the fragmentation ions in relation to the molecular ion and the intensity relative to the major ion. For example: EIMS (probe) 70 eV, m/z (rel. int.): 386 [M]+ (36), 368 [M-H2O]+ (100), 353 [M-H2O-Me]+ (23), 275 [M-111]+ (35)

X-ray crystallography. Only essential data (e.g. a three-dimensional structural drawing with bond distances) should be included in manuscripts. A complete list of refined coordinates (as a computer print-out), together with any other relevant data not included in the manuscript should be prepared separately in a form suitable for deposit at the Cambridge Crystallographic Data Centre (World Wide Web: www.ccdc.cam.ac.uk). These data should be submitted with the manuscript, and the authors should also deposit the material at Cambridge at the time the paper is published. A note indicating this fact is to be included in the manuscript. "Crystallographic data (excluding structure factors) for the structures in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication nos. CCDC...... Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK, (fax: +44 1223 336033 or e-mail: deposit@ccdc.cam.ac.uk)."

Elemental analysis results must be given in the form: "Anal. Calcd for C13H1304N: C, 63.2; H, 5.3. Found: C, 62.9; H, 5.4."

Acknowledgements
This secion is used to provide brief credit for scientific and technical assistance, and in recognition of sponsorship through financial support and any other appropriate form of recognition.

References and Notes References: All publications cited in the text should be presented in a list of references following the text of the manuscript. In the text refer to the reference number [1] (e.g. "Since Emeléus [5] has shown that..." or "This is in agreement with results obtained later [1]"). The list of references should be arranged numerically and placed before major punctuation marks thus: [1,2]. The manuscript should be carefully checked to ensure that the spelling of author's names and dates are exactly the same in the text as in the reference list. References should be given in the following forms:

Journal Article:
[1] V.A. Petrov, C.G. Krespan, B.E.Smart, J. Fluorine Chem. 77 (1996) 139-142.
Patent:
[2] E.T. McBee, O.R. Pierce, H.M. Metz, US Patent 2 899 454 (1959).
Abstract of paper presented at meeting:
[3] J.G.Riess, in: Proceedings of the 219th American Chemical Society meeting in blood substitutes, liquid breathing, and more, all with fluorocarbons, San Francisco, CA, 27 March 2000, Fluorine Division, Paper 17.
Book:
[4] W.A. Sheppard, C.M. Sharts, Organic Fluorine Chemistry, W.A. Benjamin, New York, 1997, pp. 39-96.
An article in an edited book:
[5] H.J. Eméleus, Metallic compounds containing fluorocarbon radicals and organometallic compounds containing fluorine, in: J.H. Simons (Ed.), Fluorine Chemistry, Vol. 2, Academic Press, New York, 1954, pp.321-336 (Footnote).

Tables: Many types of data can be most effectively presented in tabular form, authors should consult a current issue for examples. Tables are numbered in sequence as they are to appear in the text, using Arabic numerals. Vertical rules should not be used. Tables should be provided for reproduction at single or double column width. Title: The title should accurately and concisely describe the content of the table. Each column should have a Column heading: these should be short-use abbreviations liberally. Most important, column headings should name the parameter and unit of measure listed in the column. Footnotes: to table may be used to expand column headings and are indicated by superscript, lower case letters a, b, c.

Figures, schemes, equations and formula charts: These should be submitted on separate pages in camera-ready form without legends. These must be cited in the text and numbered in order of appearance with Arabic numerals. Authors can indicate where the figure or scheme should appear in the text, by using bold capitalised text, e.g. 'SCHEME 1'. Line drawings, structural formulae, and instrument traces (spectra etc.) must be prepared in black on a white background. Charts and drawings produced by computer, using good graphics software, are fully acceptable if printed at a resolution of 300 dpi or better. All graphics (including chemical structures) must be supplied camera-ready, for reproduction at single or double column width (83 mm or 176 mm, respectively). Please ensure that all illustrations within a paper are consistent in type and quality. All graphics must be labeled with the figure or scheme number, and the corresponding author's name (either on the back if submitted on paper or with a clear filename if using online submission, e.g. HJEScheme1.tif). For specific enquiries on the preparation of electronic artwork, consult External link http://www.elsevier.com/artworkinstructions.

Labelling of graphs and figures - legends: Labels on the axes of graphs should indicate the parameter being plotted, the units used, and the scale. Use initial capital only, put units of measure in parentheses e.g. 103 x concentration (M). Figure legends should be printed on separate sheets for inclusion in the manuscript. The legend should give the figure title, if needed an explanation of the symbols used, and any necessary information about experimental conditions. When complete details of experimental conditions are given in the legend, these should not be duplicated in the text.

Chemical formula charts and schemes: Structural formulae should be grouped for insertion in the text at appropriate points. Such group need not have a caption, but those showing reaction sequences (i.e., containing arrows) should be designated Scheme 1, Scheme 2, etc. Compound numbers should be in boldface and run sequentially through the manuscript. In charts and schemes the general progression of the formula numbers must be in sequence from left to right across the page, regardless of the order of appearance of the formulae in the text. Where a single structure with R groups represents two or more compounds, the sequence follows the listing below the structure, then resumes ite rightward progression, Multiple listings under a single formula should be in 'tabular' format, as in the following example: (see pdf file for graphic).

Authors using ChemDraw or ISISDraw for scheme / figure preparation are encouraged to use the ACS preference settings (font 10 pt Helvetica, chain angle 120°, bond spacing 18% of length, fixed length 14.4 pt (0.508 cm), bold width 2.0 pt (0.071 cm), line width 0.6 pt (0.021 cm), margin width 1.6 pt (0.056 cm), and hash spacing 2.5 pt (0.088 cm)). Authors using ChemIntosh or ChemWindow should use the 'JOC style'.

Line Width: Lines in drawings, spectral traces, etc. must be sufficiently heavy to remain sharp and distinct after eduction to single or double column width (83 mm or 176 mm, respectively). In case of doubt authors should test drawings by making reduced copies and examining them.

Lettering size and fonts: Similarly, lettering on formulae, figure axes, etc. must be large enough to be legible after reduction to single or double column width. This means a height, for capital letters in the reduced copy, of not less than 1.5 mm in formula charts, 2.0 mm on the axes of graphs. If lettering is done by computer the preferred font is Helvetica (Arial).

Half-tone photographs must have good contrast and not be more than 25 cm wide and ot more than 30 cm high. Original photographs must be supplied as they are to be reproduced (e.g. black and white or colour). If necessary, a scale should be marked on the phtotgraph. Please note that photocopies of photographs are not acceptable.

Colour illustrations: Illustrations can be printed in colour when they are judged by the Editor to be essential to the presentation. The publisher and author will each bear part of the extra costs involved. The charge to be passed on to authors of articles containing colour figures will be given on request by contacting e-mail: authors@elsevier.com.

Errata and Corrigenda to published articles will be included, at the discretion of the Regional Editors and the Publisher.

Language: Papers will be published in English, German or French. Author's manuscripts must be consistent in style, spelling and syntax. Authors in Japan please note that infomation about how to have the English of your paper checked, corrected and improved (before submission) is available from: Elsevier Japan, 15 Higashi Azabu, 1-chrome, Minato-ku, Tokoyo 106-0044, Japan, Tel: +81 3 5561 5047, e-mail: info@elsevier.co.jp.

Estimation of Length: For a rough estimate of the final length of their printed article, authors should count 850 words per full two-column page and four illustrations per page.

Page Charges
There are no page charges for The Journal of Fluorine Chemistry (other than for the inclusion of colour figures).

Book Reviews
Books suitable for review in the Journal should be sent to one of the Regional Editors.

Tracking your manuscript
The Editor will acknowledge the receipt of the authors manuscript and will allocate a provisional reference number which must be quoted in all correspondence. If the manuscript is accepted the Editor will forward the final manuscript to Elsevier, who will acknowledge the reciept of the final manuscript and allocate an Elsevier reference number (e.g. FLUOR 1234). Authors can use this new reference number to follow the progress of their accepted article through the track a paper feature.

Proofs
One set of page proofs in PDF format will be sent by e-mail to the corresponding author, to be checked for typesetting/editing. No changes in, or additions to, the accepted (and subsequently edited) manuscript will be allowed at this stage. Proofreading is solely your responsibility. A form with queries from the copyeditor may accompany your proofs. Please answer all queries and make any corrections or additions required. Please return the proofs within 48 hours of receipt.

As soon as gallery proofs have been prepared, articles will be published online as an Article in Press on ScienceDirect (www.sciencedirect.com). Articles in Press take full advantage of the enhanced ScienceDirect functionality, including the ability to be cited. This is possible due to the innovative use of the DOI article identifier, which enables the citation of a paper before volume and issue numbers are allocated. The Article in Press papers will automatically be replaced online as soon as the final version of the article in the printed journal has been published.

Offprints
The corresponding author, at no cost, will be provided with a PDF file of the article via e-mail. The PDF file is a watermarked version of the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use.

Copyright
Upon acceptance of an article, authors will be asked to transfer copyright. This transfer will ensure the widest possible dissemination of information. A letter will be sent to the corresponding author confirming receipt of the manuscript. A form facilitating transfer of copyright will be provided. If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases: contact ES Global Rights Department, P.O. Box 800, Oxford, OX5 1DX, UK; phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: permissions@elsevier.com.

Author enquiries
Authors can keep a track on the progress of their accepted article, and set up email alerts informing them of changes to their manuscript's status, by using the "Track a Paper" at External link http://ees.elsevier.com/fluor.
Full details for the electronic submission of artwork can be obtained from: External link http://www.elsevier.com/artworkinstructions.
Contact details for questions arising after acceptance of an article, especially those relating to proofs, are provided when an article is accepted for publication. Additional information on the journal, including a detailed Guide for Authors may be found on the Elsevier web site: External link http://www.elsevier.com/fluor

Graphical Abstract Template
please see the pdf file for the illustration
The size of the graphical abstract is 177mm wide by 53 mm tall. Ideally the graphic should be no larger that 65 mm wide by 45 mm high. The typesetter will insert the paper reference in the top right section (63mm x 6mm), the author(s), author(s) affiliation and address(es) will also be included in the remaining space. Authors should ensure that all items including the brief textual abstract do not exceed the space defined by the template.
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