Official journal of the Controlled Release Society, and of the Japanese Society of Drug Delivery Systems
Guide for Authors
1. Scope of the journal
The journal publishes papers innovative, original research involving the controlled release and delivery
of drugs and other biologically active agents. The terms "controlled release" and "delivery" are used in their broadest sense to include
mechanisms such as diffusion, chemical and enzymatic reactions, dissolution, osmosis, targeting, as well as the utilization and manipulation
of biological processes. A broad spectrum of studies dealing with all aspects of controlled release and delivery, including gene delivery,
tissue engineering and diagnostic agents, is encouraged. The use of prodrugs and carriers such as water-soluble polymers, micro and nanoparticles,
liposomes and micelles is included in the scope.
Papers that provide no new concepts or mechanistic insights will not be considered.
The Letter of Submission should explain in one paragraph the originality and significance of the submitted work. The manuscript will
not be processed without this information.
2. Preparation of manuscripts
Manuscript Types
It is recommended that
all articles do not exceed a total of 14 single-spaced, font size 12, typewritten pages, including references, tables, figure legends
and figures. Review articles are allowed up to 28 pages. Please note that figures and tables should be embedded in the text as close
as possible to where they are initially cited. It is also mandatory to upload separate graphic and table files as these will be required
if your manuscript is accepted for publication.
Preparation of supplementary data. Elsevier accepts supplementary
material to support and enhance your scientific research. Supplementary files offer the author additional possibilities to publish supporting
applications, movies, animation sequences, high-resolution images, background datasets, sound clips and more. Supplementary files supplied
will be published online only alongside the electronic version of your article in Elsevier Web products, including ScienceDirect:
http://www.sciencedirect.com. In order to ensure that your submitted material is directly usable, please ensure that data
is provided in one of our recommended file formats. Authors should submit the material in electronic format together with the article
and supply a concise and descriptive caption for each file. For more detailed instructions please visit our artwork instruction pages
at http://www.elsevier.com/artworkinstructions.
For supplementary materials to be published in Journal of Controlled
Release, text must be prepared with single space, and figures and tables should be inserted within the text of the supplementary
materials.
General procedures
The language of the Journal is English. Manuscripts must be written in the third person
and, when possible, in the past tense. The authors should ensure that they have written entirely original works, and if the authors have
used the work and/or words of others, this has been appropriately cited or quoted.An author should not in general publish manuscripts
describing essentially the same research in more than one journal of primary publication. Plagiarism in all its forms as well as submission
of the same manuscript to more than one journal concurrently constitutes unethical publishing behaviour and are unacceptable.Thus, the
Letter of Submission should explain in one paragraph the originality and significance of the submitted work. The manuscript will not
be processed without this information.
The following format and order of presentation is suggested:
Title, author(s), address(es).
The title should be no longer than 100
letters and spaces. The address should include the country mailing or *Zip*
code when available,
as well as the telephone and fax numbers, and e-mail
address. Indicate to whom correspondence and
proofs should be sent.
Abstract.
The abstract should present a summary of the problem, scientific
method, major findings and conclusions, in no more than 200 words and
one
paragraph. Unsubstantiated speculation should not be included. Footnotes
may not be used. References, if cited, must provide complete
publication
data.
Keywords (5)
Introduction. The purpose of this section is not to review the literature,
but to
briefly introduce the objective of the research and its significance.
Materials and methods. Procedures should be described
in sufficient detail to permit others to repeat and reproduce the results of the work. Sources of commercial products need not be listed
unless unique. Published methods need not be restated but must be referenced. Where the reference is to papers under review or in press,
copies should be provided to the Editor to facilitate review. Full chemical names of drugs/polymers/exipients, etc. should be given.
Trade names should not be used. Appropriate statistical analysis of data should be provided.
The Declarations of Helsinki and Tokyo
for humans, and the European Community guidelines as accepted principles for the use of experimental animals, must be adhered to. Therefore,
the Journal of Controlled Release will only consider manuscripts that describe experiments that have been carried out under approval
of an institutional or local ethics committee. Authors must state in the manuscript that the protocol complies with the particular recommendation
and that approval of their protocols was obtained.
Full chemical names of drugs/polymers/exipients, etc. should be given. Trade names
should not be used. Appropriate statistical analysis of data should be provided.
Results. Tables and Figures that summarize
the results and improve their
comprehension are encouraged, but only if the space required is not
excessive and less than can be stated
in the text.
The reproducibility and statistical significance of measurements, material
or biological, must be included when relevant.
Discussion. This section should deal with the interpretation of the
results and their significance to the field of study.
Repetition of
information presented in other sections should be avoided, as should general
reviews of the literature. In some cases
it may be advantageous to combine
the Results and Discussion sections.
Conclusion (optional). A short, one paragraph summary
of the most important finding(s)
of the research.
Acknowledgment (if any). Recognition of financial support, technical
assistance
and advice.
References. Responsibility for the accuracy of bibliographic citations lies entirely with authors. Number consecutively
throughout the text and
supply a separate Reference List. Abbreviate according to the'Bibliographic Guide for Editors and Authors',
1974 (Chemical
Abstracts Service, The Ohio State University, Columbus, OH 43210)
and the 'List of Serial Title Word Abbreviations',
1985, ISDS, 20
rue Bachaumont, 75002 Paris, France; ISBN 2-904938-02-8.
Examples:
Journal:
[1] E. Porges, B. Schade,
W. Ropte, Automated flow-through method
to determine the dissolution rate of slightly soluble substances,
Pharm. Ind. 47(1) (1985) 77-86.
[3] S.L. Ali, Nifedipine, in: K. Florey (Ed.), Analytical Profiles
of Drug Substances, Vol. 18, Academic Press,
New York, 1989, pp.
221-288.
Patent:
[4] J.B. Phipps, D.F. Untereker, Iontophoresis apparatus and
methods of producing
same, U.S. Patent 4, 744, 787, May 17,
1988.
Report:
[5] N.F. Cardarelli, K.E. Walker, G. Zweig, Development of
registration
criteria for controlled release pesticide
formulations, U.S. Environmental Protection Agency, Washington, DC
20460, EPA-504/9077-916,
January 1978. Articles in Special Issues: Please ensure that the words 'this issue' are added (in the list and text)
to any references to other articles in this Special Issue.
Use of Digital Object Identifier (DOI):
The digital object
identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which
is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is
an ideal medium for citing a document particularly "Articles in press" because they have not yet received their full bibliographic information.
The correct format for citing a DOI is shown as follows: doi:10.1016/j.conrel.2004.11.016
Tables. Number consecutively and
type on a numbered, separate page. Please use arabic numerals and supply a heading. Column headings should be explanatory and carry units.
Figures. Number consecutively with Arabic numerals. Figures should be used to illustrate experimental results clearly. Authors
are requested to submit figures for a one-column width where possible and ensure that symbols, lettering and lines are sufficiently large
and clear to be legible. Figure width is approximately 3 inches or 7.5 cm. Legends for each figure should be typed on a separate page.
Colour illustrations should be submitted as original photographs, high-quality computer prints or transparencies, close to
the size expected in publication, or as 35 mm slides. Polaroid colour prints are not suitable. If, together with your accepted article,
you submit usable colour figures then Elsevier will ensure, at no additional charge, that these figures will appear in colour on the
web (e.g., ScienceDirect and other sites) regardless of whether or not these illustrations are reproduced in colour in the printed version.
For colour reproduction in print, you will receive information regarding the total cost from Elsevier after receipt of your accepted
article. The 2008 price for colour figures is 285 Euro for the first page and 191 Euro for subsequent pages.
Please note: Because of
technical complications which can arise by converting colour figures to 'grey scale' (for the printed version should you not
opt for colour in print) please submit in addition usable black and white prints corresponding to all the colour illustrations.
Units and abbreviation. SI units should be used: English units or other equivalents should be given in parentheses if necessary.
On graphs, if values are recorded in non-SI units, then additional scales in SI units should be used. If a large number of symbols are
used, it is helpful if authors submit a list of these symbols and their meanings.
After
registration, authors will be asked to upload their manuscript and associated artwork. Full instructions on how to use the online submission
tool are available at the web address listed above.
Persons considering submitting a 'Review' article are encouraged to
send an outline and a CV to the Review Editor.
Review Editor
Prof. V.P. Torchilin, School of Pharmacy, Bouve
College of Health Sciences, Northeastern University, Mugar Building, Room 312, 360 Huntington Ave, Boston, MA 02115, USA; e-mail: v.torchilin@neu.edu
4. Journal Publishing Agreement and Permissions
Upon acceptance of an article, authors will be asked to sign
a 'Journal Publishing Agreement' (for more information on this and copyright see http://www.elsevier.com/copyright).
Acceptance of the agreement will ensure the widest possible dissemination of information. An e-mail (or letter) will be sent to the corresponding
author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version
of this agreement.
Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation
within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other
derivative works, including compilations and translations (please consult http://www.elsevier.com/permissions).
If excerpts
from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s)
in the article. Elsevier has preprinted forms for use by authors in these cases: please consult http://www.elsevier.com/permissions.
Authors' rights
As an author you (or your employer or institution) retain certain rights; for details you are referred
to: http://www.elsevier.com/authorsrights.
5. Correcting proofs and reprints
Elsevier will send PDF proofs
to authors by e-mail for correction. If an author is unable to handle this process, regular print proofs will be sent. Elsevier will
do everything possible to get the article corrected and published as quickly and accurately as possible. Therefore, it is important to
ensure that all corrections are sent back in one communication. Subsequent corrections will not be possible. Only typesetting errors
may be corrected; no changes in, or additions to, the accepted manuscript will be allowed. Proofs should be returned to Elsevier within
48 hours.
The Journal of Controlled Release has no page charges. The corresponding author, at no cost, will be provided
with a PDF file of the article via e-mail or, alternatively, 25 free paper offprints. The PDF file is a watermarked version of the published
article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of use. Additional
paper offprints can be ordered by the authors. An order form with prices will be sent to the corresponding author.
Language Services
Authors who require information about language editing and copyediting services pre- and post-submission please visit http://www.elsevier.com/locate/languagepolishing
or contact authorsupport@elsevier.com for more information. Please note Elsevier neither endorses nor takes responsibility
for any products, goods or services offered by outside vendors through our services or in any advertising. For more information please
refer to our Terms & Conditions http://www.elsevier.com/termsandconditions.
Funding body agreements and policies
Elsevier has established agreements and developed policies to allow authors who publish in Elsevier journals to comply with potential
manuscript archiving requirements as specified as conditions of their grant awards. To learn more about existing agreements and policies
please visit http://www.elsevier.com/fundingbodies.
For enquiries relating to the submission of articles (including
electronic submission where available) please visit this journal's homepage at http://www.elsevier.com/locate/jconrel.
You can track accepted articles at http://www.elsevier.com/trackarticle and set up e-mail alerts to inform you of when an
article's status has changed. Also accessible from here is information on copyright, frequently asked questions and more.
Contact
details for questions arising after acceptance of an article, especially those relating to proofs, will be provided by the publisher.
