Guide for Authors
Tetrahedron Letters offers rapid publication of important
new developments in organic chemistry. Articles should be in the form of short communications announcing either experimental or theoretical
results of special interest.
The contents of papers are the sole responsibility of the authors, and publication shall not imply
the concurrence of the Editors or Publisher.
Page charges
This journal
has no page charges.
Ethics in publishing
For information on Ethics in publishing and Ethical guidelines for journal publication see
http://www.elsevier.com/publishingethics
and
http://www.elsevier.com/ethicalguidelines.
Conflict of interest
All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other
relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence,
or be perceived to influence, their work. See also
http://www.elsevier.com/conflictsofinterest.
Submission declaration
Submission of an article implies that the work described has not been published previously
(except in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication
elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was
carried out, and that, if accepted, it will not be published elsewhere including electronically in the same form, in English or in any
other language, without the written consent of the copyright-holder.
Submission declaration
and verification
Submission of an article implies that the work described has not been published previously (except in the
form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication elsewhere,
that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out,
and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically
without the written consent of the copyright-holder. To verify originality, your article may be checked by the originality detection
software iThenticate. See also
http://www.elsevier.com/editors/plagdetect.
Changes to authorship
This policy concerns the addition, deletion, or rearrangement of author names in the authorship
of accepted manuscripts:
Before the accepted manuscript is published in an online issue: Requests to add or remove an author,
or to rearrange the author names, must be sent to the Journal Manager from the corresponding author of the accepted manuscript and must
include: (a) the reason the name should be added or removed, or the author names rearranged and (b) written confirmation (e-mail, fax,
letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors,
this includes confirmation from the author being added or removed. Requests that are not sent by the corresponding author will be forwarded
by the Journal Manager to the corresponding author, who must follow the procedure as described above. Note that: (1) Journal Managers
will inform the Journal Editors of any such requests and (2) publication of the accepted manuscript in an online issue is suspended until
authorship has been agreed.
After the accepted manuscript is published in an online issue: Any requests to add, delete, or
rearrange author names in an article published in an online issue will follow the same policies as noted above and result in a corrigendum.
Copyright
Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement'
(for more information on this and copyright see
http://www.elsevier.com/copyright). Acceptance of the agreement will ensure
the widest possible dissemination of information. An e-mail will be sent to the corresponding author confirming receipt of the manuscript
together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
Subscribers may reproduce
tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of
the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations
and translations (please consult
http://www.elsevier.com/permissions). If excerpts from other copyrighted works are included,
the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted
forms for use by authors in these cases: please consult
http://www.elsevier.com/permissions.
Retained author rights
As an author you (or your employer or institution) retain certain rights; for details
you are referred to:
http://www.elsevier.com/authorsrights.
Role of the
funding source
You are requested to identify who provided financial support for the conduct of the research and/or preparation
of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation
of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such
involvement then this should be stated. Please see
http://www.elsevier.com/funding.
Funding body agreements and policies
Elsevier has established agreements and developed policies to allow authors whose
articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specified as conditions
of their grant awards. To learn more about existing agreements and policies please visit
http://www.elsevier.com/fundingbodies.
Language and language services
Please write your article in clear, concise, grammatically correct
English (American or British usage is accepted, but not a mixture of these). Authors who require information about language editing and
copyediting services pre- and post-submission please visit
http://www.elsevier.com/languageediting or our customer support
site at
http://epsupport.elsevier.com for more information.
Language
Editing
International Science Editing and Asia Science Editing can provide English language and copyediting services to authors
who want to publish in scientific, technical, and medical journals and need assistance before they submit their article or before it
is accepted for publication. Authors can contact these services directly: International Science Editing (
http://www.internationalscienceediting.com)
and Asia Science Editing (
http://www.asiascienceediting.com) or, for more information about language editing services, authors
may contact
authorsupport@elsevier.com who will be happy to deal with any questions. Please note Elsevier neither endorses
nor takes responsibility for any products, goods, or services offered by outside vendors through our services or in any advertising.
For more information please refer to our terms and conditions (
http://authors.elsevier.com/terms_and_conditions.html).
Journal policy
Submission of an article implies that the work described has not been published previously (except
in the form of an abstract or as part of a published lecture or academic thesis), that it is not under consideration for publication
elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was
carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, without
the written consent of the copyright holder. Authors accept full responsibility for the factual accuracy of the data presented and should
obtain any authorization necessary for publication. As such the contents of the papers are the sole responsibility of the authors and
publication shall not imply the concurrence of the editors or copyright holder.
All papers are submitted to referees who advise the
editor on the matter of acceptance in accordance with the high standards required, on the understanding that the subject matter has not
been previously published and is not under consideration elsewhere. Referees will be asked to distinguish contributions meeting the above
requirements and having an element of novelty, timeliness, and urgency that merits publication in the journal. We ask referees to help
in the selection of articles that have this breadth and suggest that papers covering narrower aspects of the field be sent to journals
specializing in those areas. Referee names are not disclosed, but their views are forwarded by the editor to the authors for consideration.
Authors are encouraged to suggest names of several experts in the field when papers are first submitted or at any time in the evaluation
process.
Submission
Submission to this journal proceeds totally online
and you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a
single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted
to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence,
including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.
MANUSCRIPT SUBMISSION
Articles
Authors should submit their manuscripts to the appropriate regional
editor (see below) via the online submission page of this journal at
http://ees.elsevier.com/tetl. Authors will be guided
stepwise through the creation and uploading of the various files. The system automatically converts source files to a single Adobe Acrobat
PDF version of the article, which is used in the peer review process. Please note that even though manuscript source files are converted
to PDF at submission for the review process, these source files are needed for further processing after acceptance. All correspondence,
including notification of the editor's decision and requests for revision, takes place by e-mail and via the author's home page. A printed
copy of the manuscript is not required at any stage of the process.
The following items should be submitted to the appropriate regional
editor via the online submission page:
-
Manuscript. It is not necessary to embed graphics in the text, but if you
do so please note that separate graphic files will always be required for proof production when a manuscript is accepted for publication.
Graphics should be submitted as separate, highresolution artwork files. These will be automatically incorporated into the single PDF
that the system creates for review.
-
Graphical abstract for the contents list (submitted as a separate document).
-
Cover letter: highlighting the novelty, significance, and urgency of the submitted work, which merits rapid publication
and providing details of other relevant information, e.g., submitted or in press manuscripts.
-
List of potential referees
(Separate document).
-
Mol files (optional): Elsevier would like to enrich online articles by visualising and providing
details of chemical structures you define as the main chemical compounds described in your article. For this purpose, corresponding mol
files can be uploaded in EES. Each compound needs to be submitted as a separate mol file. Please use your preferred drawing tool to export
chemical structures as mol files and ensure that they are unique, complete and do not contain any R-Groups or other variables to generate
a correct InChI key.
More information on MOL
files
For information on how to create MOL files please see
here
More information.
Manuscripts should be addressed to the appropriate regional editor:
Articles
from Austria, Belgium, France, Germany, Portugal, Spain and Switzerland:
Professor S. Z. Zard, Laboratoire de Synthèse
Organique, École Polytechnique, F-91128 Palaiseau Cedex, France.
China:
Professor Lin Guo-Qiang, Shanghai
Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China (manuscripts from Taiwan may be
sent to Professor Lin, or to the usual Editor in Japan, at the choice of the authors).
Japan and South Korea:
Professor Y. Yamamoto, Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
India:
Professor S. Chandrasekaran, Department of Organic Chemistry, Indian Institute of Science, Bangalore-560 012, India.
The
Americas:
Asymmetric and Combinatorial Synthesis, Heterocycles, Organometallic Chemistry, Physical Organic Chemistry,
Radicals, Small Rings, Strained Systems, Theory and Total Synthesis
Professor J. Wood, A. I. Meyers Professor of Chemistry,
Department of Chemistry, Colorado State University, Fort Collins, CO 80523-1872, USA.
General Synthetic and Combinatorial
Methods, Bioorganic Chemistry, Heterocycles, Natural Products, Carbohydrates and Photochemistry
Professor B. Ganem, Department
of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY 14853-1301, USA.
All regions other than those
specified above:
Professor E. J. Thomas, Department of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL,
UK.
Templates are provided in order to allow authors to view their paper in a style close to the final printed form.
Their use is
optional. The templates can be found at
http://www.elsevier.com/wps/find/P04_116.cws_home/authors_guide.
All manuscripts
will be fully typeset from the author's electronic files. It should be noted that due to defined typesetting standards and the complex
requirements of electronic publishing, the Publisher will not always be able to exactly match the layout the author has submitted. In
particular, in the finished journal article, figures and tables are usually placed at the top or bottom of pages. The template is only
intended to be used in assisting with the preparation and submission of manuscripts.
It should be noted that the use of the journal
template is not a requirement and its adoption will neither speed nor delay publication. Elsevier can handle most major word processing
packages and in general most formatting applied by authors for style and layout is replaced when the article is being typeset.
These
templates contain a large number of macros. To ensure successful PDF conversion by the online submission system, it is important that
the author saves a new document based on the template, rather than saving the template itself. To use the template, the author should
save the final document as a Word file with a ".doc" extension (rather than the ".dot" extension). Please use TrueType fonts in order
to avoid problems with the creation of the PDF.
Please ensure that the graphical abstract is included as page 1 of your manuscript
when submitting online. For detailed instructions on the preparation of electronic artwork, consult Elsevier's Author Gateway at
http://www.elsevier.com/wps/find/authors.authors/authorartworkinstructions
General requirements
The corresponding author's full
mailing address, including mail codes, phone number, fax number, and e-mail address should be included. The manuscript should be compiled
in the following order: Graphical Abstract, Title, Authors, Affiliations, Abstract, Keywords, Introduction, Results, Discussion, Conclusion,
Experimental, Acknowledgments, References and Notes, Tables, Legends, Figures, and Schemes.
Text
Text should be subdivided in the simplest possible way consistent with clarity. Headings should reflect the
relative importance of the sections. Ensure that all tables, figures, and schemes are cited in the text in numerical order. The preferred
position for chemical structures should be indicated. Trade names should have an initial capital letter. All measurements and data should
be given in SI units where possible, or in other internationally accepted units. Abbreviations should be used consistently throughout
the text, and all non-standard abbreviations should be defined on first usage. Authors are requested to draw attention to hazardous materials
or procedures by adding the word
CAUTION followed by a brief descriptive phrase and literature references if appropriate.
Essential title page information
•
Title.
Concise and informative. Titles are often
used in information-retrieval systems. Avoid abbreviations and formulae where possible.
•
Author names and affiliations.
Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses
(where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the
author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name
and, if available, the e-mail address of each author.
•
Corresponding author.
Clearly indicate who will handle
correspondence at all stages of refereeing and publication, also post-publication.
Ensure that telephone and fax numbers (with country
and area code) are provided in addition to the e-mail address and the complete postal address. Contact details must be kept up to date
by the corresponding author.
•
Present/permanent address.
If an author has moved since the work described
in the article was done, or was visiting at the time, a 'Present address' (or 'Permanent address') may be indicated as a footnote to
that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript
Arabic numerals are used for such footnotes.
Abstracts
Authors must include
a short abstract of approximately four to six lines that states briefly the purpose of the research, the principal results, and major
conclusion(s). References and compound numbers should not be mentioned in the abstract unless full details are given.
Graphical abstract
A Graphical abstract is mandatory for this journal. It should summarize the contents
of the article in a concise, pictorial form designed to capture the attention of a wide readership online. Authors must provide images
that clearly represent the work described in the article. Graphical abstracts should be submitted as a separate file in the online submission
system. Image size: please provide an image with a minimum of 531 × 1328 pixels (h × w) or proportionally more. The image
should be readable at a size of 5 × 13 cm using a regular screen resolution of 96 dpi. Preferred file types: TIFF, EPS, PDF or
MS Office files. See
http://www.elsevier.com/graphicalabstracts for examples.
Authors can make use of Elsevier's Illustration
and Enhancement service to ensure the best presentation of their images also in accordance with all technical requirements:
Illustration Service.
Keywords
Authors
are asked to provide four keywords, which will be used for indexing purposes.
Acknowledgements
An acknowledgement section may be included. It should be placed after the manuscript text and before the references.
Nomenclature
It is the responsibility of the authors to provide correct nomenclature. Chemical names for
drugs are preferred. If these are not practical, generic names, names approved by the U.S. Adopted Names Council, or those approved by
the World Health Organization may be used. If a generic name is used, its chemical name or structure should be provided at the point
of first citation. Authors will find the following as useful reference books for recommended nomenclature.
IUPAC Nomenclature
of Organic Chemistry; Rigaudy, J.; Klesney, S. P., Eds; Pergamon: Oxford, 1979.
Enzyme Nomenclature; Webb, E. C., Ed.;
Academic Press; Orlando, 1992.
Biochemical Nomenclature and Related Documents; The Biochemistry Society; London, 1978.
The ACS Style Guide; Dodd, J. S., Ed.; American Chemical Society: Washington, DC, 1997.
X-ray crystallographic data
Prior to submission of the manuscript, the author should deposit crystallographic data for
organic and metalorganic structures with the Cambridge Crystallographic Data Centre. The data, without structure factors, should be sent
by e-mail to
deposit@ccdc.cam.ac.uk, as an ASCII file, preferably in CIF format. Hard copy data should be sent to CCDC,
12 Union Road, Cambridge CB2 1EZ. A checklist of data items for deposition can be obtained from the CCDC Home Page on the World Wide
Web (
http://www.ccdc.cam.ac.uk) or by e-mail to:
fileserv@ccdc.cam.ac.uk, with the one-line message, send
me checklist. The data will be acknowledged, within three working days, with one CCDC deposition number per structure deposited. These
numbers should be included with the following standard text in the manuscript: Crystallographic data (excluding structure factors) for
the structures in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication nos. CCDC.
Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK, (fax: +44-(0)1223-336033
or e-mail:
deposit@ccdc.cam.ac.Uk). Deposited data may be accessed by the journal and checked as part of the refereeing
process. If data are revised prior to publication, a replacement file should be sent to CCDC.
Characterization of new compounds
All new compounds should be fully characterized with relevant spectroscopic data. Microanalyses should be included whenever possible.
Under appropriate circumstances, high-resolution mass spectra may serve in lieu of microanalysis, if accompanied by suitable NMR criteria
for sample homogeneity.
DNA sequences and GenBank Accession numbers
Many
Elsevier journals cite ''gene accession numbers'' in their running text and footnotes. Gene accession numbers refer to genes or DNA sequences
about which further information can be found in the databases at the National Center for Biotechnical Information (NCBI) at the National
Library of Medicine. Elsevier authors wishing to enable other scientists to use the accession numbers cited in their papers via links
to these sources, should type this information in the following manner:
For each and every accession number cited in an
article, authors should type the accession number in
bold, underlined text. Letters in the accession number should always
be capitalised. (See Example below). This combination of letters and format will enable Elsevier's typesetters to recognise the relevant
texts as accession numbers and add the required link to GenBank's sequences.
Example: ''(GenBank accession nos.
AI631510,
AI631511
,
AI632198
, and
BF223228
), a B-cell tumor from a chronic lymphatic leukemia (GenBank
accession no. BE675048), and a T-cell lymphoma (GenBank accession no. AA361117)''. Authors are encouraged to check accession numbers
used very carefully.
An error in a letter or number can result in a dead link. In the final version of the
printed
article, the accession number text will not appear bold or underlined. In the final version of the
electronic copy,
the accession number text will be linked to the appropriate source in the NCBI databases enabling readers to go directly to that source
from the article.
Footnotes
Footnotes should appear at the bottom of
the appropriate page and be indicated by the following symbols: asterisk, dagger, double dagger, section sign, paragraph, parallels.
Artwork
Figures, schemes, and equations must be cited in the text and numbered in order of appearance
with Arabic numerals. Other graphics, such as structures, do not need to be numbered, but please indicate in the text where these are
to appear. All graphics (including chemical structures) must be provided at the actual size that they are to appear (single-column width
is 8.4 cm, double-column width is 17.7 cm). Please arrange schematics so that they fill the column space (either single or double), so
as not to leave a lot of unused white space. Please ensure that all illustrations within a paper are consistent in type, quality, and
size. Legends should not be included as part of the graphic; instead all legends should be supplied at the end of the text.
To help
authors provide actual size graphics, it is suggested that the following settings be used with CSC ChemDraw and ISIS Draw: font 10 pt
Helvetica, chain angle 120°, bond spacing 18% of length, fixed length 10.08 pt (0.354 cm), bold width 1.4 pt (0.049 cm), line width
0.42 pt (0.015 cm), margin width 1.12 pt (0.040 cm), and hash spacing 1.75 pt (0.062 cm). Compound numbers should be in boldface. In
order to accurately design schematics to print out at the proper width, the original drawing cannot exceed a column width of 8.4 cm (for
single column) and 17.7 cm (for double column). Layout design is facilitated if authors submit their original artwork in the actual size
to be published. Please save graphics as an Encapsulated PostScript file (EPS) or a Tagged Image File Format (TIFF), as well as the program
the graphic was originally drawn in. For more details on the preparation and submission of artwork, please visit
www.authors.elsevier.com.
Colour
Colour figures should be supplied in electronic format as JPEG files (minimum 300 dots per inch).
-
In print: Colour figures may be printed in the journal at no charge to the author, provided that the editor considers
the colour necessary to convey scientific information.
-
On the Web: Any figure can appear free of charge in colour in the
Web version of your article (e.g., on ScienceDirect), regardless of whether or not this is reproduced in colour in the printed version.
Please note that if you do not opt for colour in print, you should submit relevant figures in both colour (for the Web) and black and
white (for print).
Legends
Legends for figures and schemes should
be grouped together separately.
Tables
All tables should be cited in
the text, and numbered in order of appearance with Arabic numerals. All table columns should have a brief explanatory heading and, where
appropriate, units of measurement. Vertical lines should not be used. Footnotes to tables should be typed below the table and should
be referred to by superscript letters. Each table should have a descriptive heading, which, together with the individual column headings,
should make the table, as nearly as possible, self-explanatory. In setting up tabulations, authors are requested to keep in mind the
column widths (8.4 cm and 17.7 cm), and to make the table conform to the limitations of these dimensions.
References and notes
In the text, references should be indicated by superscript Arabic numerals which run
consecutively through the paper and appear after any punctuation. Please ensure that all references are cited in the text and vice versa.
The reference list should preferably contain only literature references, although other information (e.g., experimental details) can
be placed in this section. Preferably, each reference should contain only one literature citation. Authors are expected to check the
original source reference for accuracy. Journal titles should be abbreviated according to American Chemical Society guidelines (
The
ACS Style Guide; Dodd, J. S., Ed.; American Chemical Society: Washington DC, 1997). A list of currently accepted journal abbreviations
may be found the journal home page at
www.elsevier.com/locate/tetl. Formatting for common references are shown below.
Scientific articles:
1. Barton, D. H. R.; Yadav-Bhatnagar, N.; Finet, J.-P.; Khamsi, J.
Tetrahedron Lett. 1987,
28,
3111.
Books:
2. Doe, J. S.; Smith, J. In
Medicinal Chemistry; Roe, P., Ed.; Pergamon: Oxford, 1990; Vol. 1, pp 301 383.
Patent/Chem. abstract:
3. Lyle, F. R. U.S. Patent 6,973,257, 1995;
Chem. Abstr. 1995,
123, 2870.
Meeting abstract:
4. Prasad, A.; Jackson, P.
Abstracts of Papers, Part 2, 212th National Meeting of the American Chemical
Society, Orlando, FL, Aug 25-29, 1996; American Chemical Society: Washington, DC, 1996; PMSE 189.
Citing and listing of Web references
As a minimum, the full URL should be given. Any further information, if known (author names, dates, reference to a source publication,
etc.), should also be given. Web references can be listed separately (e.g., after the reference list) under a different heading if desired,
or can be included in the reference list.
Abbreviations
Standard ACS
abbreviations should be used throughout the manuscript and are employed without periods. The preferred forms for some of the more commonly
used abbreviations are mp, bp, °C, K, min, h, mL, μL, g, mg, μg, cm, mm, nm, mol, mmol, μmol, M, mM, μM, ppm, HPLC,
TLC, GC, 1H NMR, GC-MS, HRMS, FABHRMS, UV, IR, EPR, ESR, DNase, ED50, ID50, IC50, LD50, im, ip, iv, mRNA, RNase, rRNA, tRNA, cpm, Ci,
dpm,
Vmax,
Km,
k,
t1/2. All non-standard abbreviations should be defined following the first use
of the abbreviation. For a detailed listing of standard abbreviations, see The ACS Style Guide; American Chemical Society: Washington,
DC, 1997.
Software
Software used as part of computer-aided drug/agent
design (e.g., molecular modelling, QSAR, conformational analysis, molecular dynamics) should be readily available from accepted sources
and the authors may specify where the software can be obtained. Assurance of the quality of the parameters employed for the relevant
potential functions should be detailed in the manuscript.
Preparation of supplementary data
Elsevier accepts electronic
supplementary material to support and enhance your scientific research. Supplementary files offer the author additional possibilities
to publish supporting applications, movies, animation sequences, high-resolution images, background datasets, sound clips, and more.
Supplementary files supplied will be published online alongside the electronic version of your article in Elsevier web products, including
ScienceDirect:
www.sciencedirect.com.
To ensure that your submitted material is directly usable, please provide data
in one of our recommended file formats. Supplementary data must be saved in files separate from those for the manuscript and figures,
and all file names must be supplied. Supplementary files should either be referred to from within the text of your manuscript in the
same way as for figures or tables, or their presence be indicated by adding a paragraph entitled "Supplementary data" at the end of the
manuscript, detailing which data are supplied. In addition, authors should also provide a concise and descriptive caption for each file.
When supplying supplementary data, authors must state whether the data files are either (i) for online publication or (ii) to be used
as an aid for the refereeing of the paper only. All supplementary data will be subject to peer review. For more detailed instructions,
please visit Elsevier's Author Gateway at
http://authors.elsevier.com, and click on "Artwork instructions", then "Multimedia
files".
Mol Files
Mol files (optional): Elsevier would like
to enrich online articles by visualising and providing details of chemical structures you define as the main chemical compounds described
in your article. For this purpose, corresponding mol files can be uploaded in EES. Each compound needs to be submitted as a separate
mol file. Please use your preferred drawing tool to export chemical structures as mol files and ensure that they are unique, complete
and do not contain any R-Groups or other variables to generate a correct InChI key.
More
information
For information on how to create MOL files please see
here
Use of the Digital Object
Identifier
The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of
a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The
assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have
not yet received their full bibliographic information. The correct format for citing a DOI is shown as follows (example taken from a
document in the journal
Physics Letters B):
doi:10.1016/j.physletb.2010.09.059
When you use the DOI to create URL hyperlinks
to documents on the web, the DOIs are guaranteed never to change.
Proofs
Proofs
will be despatched via e-mail and should be returned with corrections as quickly as possible, normally within 48 hours of receipt. Elsevier
now sends PDF proofs which can be annotated; for this you will need to download Adobe Reader version 7 available free from
http://www.adobe.com/products/acrobat/readstep2.html.
Instructions on how to annotate PDF files will accompany the proofs. The exact system requirements are given at the Adobe site:
http://www.adobe.com/products/acrobat/acrrsystemreqs.html#70win. If you do not wish to use the PDF annotations function, you may list the corrections (including replies to the Query Form) and return
to Elsevier in an e-mail. Please list your corrections quoting line number. If, for any reason, this is not possible, then mark the corrections
and any other comments (including replies to the Query Form) on a printout of your proof and return by fax, or scan the pages and e-mail,
or by post. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures.
Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor.
We will do everything possible to get your article published quickly and accurately. Therefore, it is important to ensure that all of
your corrections are sent back to us in one communication: please check carefully before replying, as inclusion of any subsequent corrections
cannot be guaranteed. Proofreading is solely your responsibility. Note that Elsevier may proceed with the publication of your article
if no response is received. Any amendments will be incorporated and the final article will then be published online as an Article in
Press on ScienceDirect (
www.sciencedirect.com).
Articles in Press take full advantage of the enhanced Science-Direct
functionality, including the ability to be cited. This is possible due to the innovative use of the DOI article identifier, which enables
the citation of a paper before volume, issue and page numbers are allocated. The Article in Press will be removed once the paper has
been assigned to an issue and the issue has been compiled.
Electronic offprints (e-offprints)
The corresponding author will be provided with a PDF file of the article via e-mail. The PDF file is a watermarked version of
the published article and includes a cover sheet with the journal cover image and a disclaimer outlining the terms and conditions of
use. Additional paper offprints can be ordered by the authors. An order form with prices will be sent to the corresponding author.
NIH voluntary posting policy
Special Subject Repositories
Certain repositories such as PubMed
Central ("PMC") are authorized under special arrangement with Elsevier to process and post certain articles such as those funded by the
National Institutes of Health under its Public Access policy (see elsevier.com for more detail on our policy). Articles accepted for
publication in an Elsevier journal from authors who have indicated that the underlying research reported in their articles was supported
by an NIH grant will be sent by Elsevier to PMC for public access posting 12 months after final publication. The version of the article
provided by Elsevier will include peer-review comments incorporated by the author into the article. Because the NIH "Public Access" policy
is voluntary, authors may elect not to deposit such articles in PMC. If you wish to "opt out" and not deposit to PMC, you may indicate
this by sending an e-mail to
NIHauthorrequest@elsevier.com.
For inquiries relating to the submission of articles (including electronic submission) please visit this journal's homepage.
Contact details for questions arising after acceptance of an article, especially those relating to proofs, will be provided by the publisher.
You can track accepted articles at
http://www.elsevier.com/trackarticle. You can also check our Author FAQs (
http://www.elsevier.com/authorFAQ)
and/or contact Customer Support via
http://support.elsevier.com.
