James Fox, Massachusetts Institute of Technology, Cambridge, U.S.A. Stephen Barthold, Center for Comparative Medicine, UC Davis School of Veterinary Medicine, Davis CA Muriel Davisson, The Jackson Laboratory, Bar Harbor, Maine Christian Newcomer, Research Animal Resources and Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, MD Fred Quimby, Laboratory Animal Research Center, The Rockefeller University, New York, NY Abigail Smith, School of Veterinary Medicine, University of Pennsylvania Philadelphia, PA
Description History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research,
provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on
maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild
mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular
organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains
and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical
mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new
to the field of mouse research.
Contents Volume I History, Genetics, and Wild Mice
1. Building a Better Mouse: One Hundred Years of Genetics and Biology
Herbert C. Morse
III
2. Systematics of the genus Mus
Priscilla K. Tucker
3. The Secret World of Wild Mice
Grant R. Singleton and Charles J. Krebs
4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types
Melissa L. Berry and Carol Cutler
Linder
5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide
Janan T. Eppig
6. The Mouse Genome
Mark D. Adams
7.
Gene Mapping
Muriel T. Davisson
8. Genetic Monitoring
Richard R. Fox, Michael V. Wiles, and Petko M. Petkov
9. Cytogenetics
Muriel T. Davisson and Mary Ann Handel
10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between
Mouse and Man
M.H. Kaufman
11. Gamete and Embryo Manipulation
K.C. Kent Lloyd
12. Chemical Mutagenesis in Mice
Martin Hrabe de
Angelis, Dian Michel, Sibylle Wagner, Sonja Becker and Johannes Beckers
13. Gene-Specific Mutagenesis
K.C. Kent Lloyd
14.
Gene Transfer Studies Using Mouse Models
Robert G. Pergolizzi and Ronald G. Crystal
15. Mouse and Human Pluripotent Stem Cells
Leslie
F. Lock
16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics
Lucia F. Jorge-Nebert, Sandrine Derkenne and
Daniel W. Nebert
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